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Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification
S. E. Deprimo
,
L. M. Wong
,
D. B. Khatry
,
S. L. Nicholas
,
W. C. Manning
,
B. D. Smolich
,
A. M. O'Farrell
, and
J. M. Cherrington
BMC.Cancer
(
2003
)
to
&
9
Aged
Analysis
Angiogenesis
Antigens
Array
Biological
Biopsy
CD
CD24
Chain
Chemistry
Clinical
Colorectal
Expression
Female
Gene
Glycoproteins
Human
Humans
III
Indoles
Inhibitors
Kinase
Kinases
Lactoferrin
Leukocytes
Male
Markers
Matrix
Membrane
Metalloproteinase
Metastasis
Middle
Mononuclear
Neoplasm
Neoplasms
Neoplastic
Oligonucleotide
Phase
Polymerase
Predictive
Profiling
Protein-Tyrosine
Pyrroles
Reaction
Regulation
Research
Reverse
Sequence
Tests
Topic
Transcriptase
Trials
Tumor
Tyrosine
Value
analysis
antagonists
as
blood
cells
drug
genetics
identify
inhibitors
metabolism
methods
of
protein
response
therapeutic
therapy
use
by
kanefendt
on
Feb 5, 2010, 11:28 AM
URL
|
BibTeX
Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
H. J. Burstein
,
A. D. Elias
,
H. S. Rugo
,
M. A. Cobleigh
,
A. C. Wolff
,
P. D. Eisenberg
,
M. Lehman
,
B. J. Adams
,
C. L. Bello
,
S. E. Deprimo
,
C. M. Baum
, and
K. D. Miller
J Clin Oncol
26(11):1810-1816
(
2008
)
to
&
Administration
Adult
Aged
Agents
Anthracyclines
Antineoplastic
Biological
Breast
Bridged
Carcinoma
Chemotherapy
Combined
Compounds
Diseases
Drug
Fatigue
Female
Gastrointestinal
Growth
Hematologic
Humans
Indoles
Inflammation
Kinase
Kinases
Markers
Middle
Neoplasms
Oral
Plasma
Protein-Tyrosine
Protocols
Pyrroles
Rate
Schedule
Survival
Taxoids
Tumor
Tyrosine
administration
adverse
analysis
antagonists
blood
chemically
classification
dosage
drug
effects
induced
inhibitors
methods
mortality
response
secondary
therapeutic
therapy
use
by
kanefendt
on
Feb 5, 2010, 11:28 AM
URL
|
BibTeX
Effect of treatment with sunitinib malate, a multitargeted tyrosine kinase inhibitor, on circulating plasma levels of VEGF, soluble VEGF receptors 2 and 3, and soluble KIT in patients with metastatic breast cancer
S. E. Deprimo
,
C. Friece
,
X. Huang
,
J. Smeraglia
,
L. Sherman
,
M. Collier
,
C. Baum
,
A. D. Elias
,
H. J. Burstein
, and
K. D. Miller
J Clin Oncol Meeting Abstracts
24(18_suppl):578
(
2006
)
to
Outcome
Proteins
Research
SU11248
Treatment
Tyrosine
analysis
methods
protein
response
therapy
by
kanefendt
on
Feb 5, 2010, 11:28 AM
URL
|
BibTeX
Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins
Samuel Deprimo
,
Carlo Bello
,
John Smeraglia
,
Charles Baum
,
Dominic Spinella
,
Brian Rini
,
M. Dror Michaelson
, and
Robert Motzer
Journal of Translational Medicine
5(1):32
(
2007
)
to
Carcinoma
Disease
Placenta
Progression
Proteins
Tyrosine
analysis
protein
response
therapy
by
kanefendt
on
Feb 5, 2010, 11:28 AM
URL
|
BibTeX
Surrogate biomarkers in evaluating response to anti-angiogenic agents: focus on sunitinib
S. E. Deprimo
, and
C. Bello
Ann.Oncol
(
2007
)
to
Angiogenesis
Biological
Cells
Endothelial
Growth
Humans
Indoles
Inhibitors
Laboratories
Markers
Neoplasms
Neovascularization
Pathologic
Proteins
Pyrroles
Research
Tumor
blood
cells
diagnosis
drug
effects
metabolism
methods
pathology
pharmacology
protein
response
supply
therapeutic
therapy
use
by
kanefendt
on
Feb 5, 2010, 11:28 AM
URL
|
BibTeX
Blood-Based Biomarkers of SU11248 Activity and Clinical Outcome in Patients with Metastatic Imatinib-Resistant Gastrointestinal Stromal Tumor
Anat Norden-Zfoni
,
Jayesh Desai
,
Judith Manola
,
Paul Beaudry
,
Jeremy Force
,
Robert Maki
,
Judah Folkman
,
Carlo Bello
,
Charles Baum
,
Sam E. DePrimo
,
David R. Shalinsky
,
Goerge D. Demetri
, and
John V. Heymach
Clin Cancer Res
13(9):2643-2650
(
2007
)
to
Cells
Endothelial
Monocytes
Population
SU11248
Tyrosine
cells
identify
by
kanefendt
on
Feb 5, 2010, 11:28 AM
URL
|
BibTeX
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Tumor
cells
Humans
use
Indoles
Markers
Pyrroles
drug
therapeutic
blood
Research
metabolism
identify
effects
&
Carcinoma
SU11248
inhibitors
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Angiogenesis
Kinase
Growth
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antagonists
Protein-Tyrosine
Middle
Aged
Kinases
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Endothelial
Gene
Profiling
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Sequence
dosage
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mortality
Clinical