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A Naturally Occurring Soluble Form of Vascular Endothelial Growth Factor Receptor 2 Detected in Mouse and Human Plasma
John M. L. Ebos, Guido Bocci, Shan Man, Philip E. Thorpe, Daniel J. Hicklin, Danielle Zhou, Xiaohong Jia, and Robert S. Kerbel Mol Cancer Res 2(6):315-326 (2004)
to Antibodies Binding Cells Endothelial Human Immunoprecipitation Molecular Tyrosine Weight cells protein by kanefendt and 1 other user on Feb 5, 2010, 11:28 AM
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A naturally occurring soluble form of vascular endothelial growth factor receptor 2 detected in mouse and human plasma
J. M. Ebos, G. Bocci, S. Man, P. E. Thorpe, D. J. Hicklin, D. Zhou, X. Jia, and R. S. Kerbel Mol.Cancer Res. 2(6):315-326 (2004)
to Animals Antibodies Binding Cell Cells Chemistry Conditioned Culture Endothelial Factor Factors Glycosylation Growth Health Human Humans Immunoprecipitation Line Media Mice Molecular Plasma Protein Receptor-2 Research Solubility Tyrosine Vascular Weight blood cells immunology metabolism protein secretion by kanefendt and 1 other user on Feb 5, 2010, 11:28 AM
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Increased plasma vascular endothelial growth factor VEGF as a surrogate marker for optimal therapeutic dosing of VEGF receptor-2 monoclonal antibodies
G. Bocci, S. Man, S. K. Green, G. Francia, J. M. Ebos, J. M. Du Manoir, A. Weinerman, U. Emmenegger, L. Ma, P. Thorpe, A. Davidoff, J. Huber, D. J. Hicklin, and R. S. Kerbel Cancer Res. 64(18):6616-6625 (2004)
to & A Adenocarcinoma Administration Angiogenesis Animals Antibodies Antineoplastic Biological Blood Cell Chemotherapy Colorectal Combined Drug Endothelial Factor Growth Human Humans Inhibitors Line Male Markers Messenger Mice Modality Monoclonal Neoplasms Neovascularization Nude Pathologic Platelets Prostatic Protocols RNA Receptor-2 Research Schedule Scid Therapy Tumor Vascular administration biosynthesis blood dosage genetics immunology metabolism protein supply therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis
Y. Shaked, F. Bertolini, S. Man, M. S. Rogers, D. Cervi, T. Foutz, K. Rawn, D. Voskas, D. J. Dumont, Y. Ben-David, J. Lawler, J. Henkin, J. Huber, D. J. Hicklin, R. J. D'Amato, and R. S. Kerbel Cancer Cell 7(1):101-111 (2005)
to A Angiogenesis Animals Antibodies Assay Biological Cell Cells Cytometry Dose-Response Drug Endothelial Factor Factors Fibroblast Flow Growth Humans Inbred Inhibitors Male Markers Mice Neovascularization Pathologic Phenotype Receptor Receptor-2 Relationship Research Stem Strains Survival TIE-2 Transgenic Vascular analysis blood cells drug effects genetics metabolism methods pharmacology physiology therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors
A. M. Petit, J. Rak, M. C. Hung, P. Rockwell, N. Goldstein, B. Fendly, and R. S. Kerbel Am.J.Pathol. 151(6):1523-1530 (1997)
to A Adenocarcinoma Animals Antibodies Breast Carcinoma Cell Cells Cultured Dose-Response Down-Regulation Drug Endothelial Epidermal Expression Factor Factors Gene Growth Human Humans Immunoenzyme Lymphokines Mice Monoclonal Neoplasm Neoplasms Neoplastic Neovascularization Neutralization Nude Oncogenes Pathologic Proliferation Receptor Regulation Relationship Research Signal Squamous Survival Techniques Tests Transduction Transplantation Tumor Tyrosine Vascular blood cells drug effects erbB-2 immunology metabolism pathology pharmacology physiology protein therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Tumor angiogenesis
R. S. Kerbel N.Engl.J.Med. 358(19):2039-2049 (2008)
to A Angiogenesis Animals Bone Cells Drug Endothelial Factor Growth Human Humans Inhibitors Marrow Neoplasm Neoplasms Neovascularization Notch Pathologic Proteins Proto-Oncogene Receptors Research Resistance Signal Transduction Vascular blood drug physiology physiopathology protein supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth
J. M. Ebos, C. R. Lee, E. Bogdanovic, J. Alami, Slyke P. Van, G. Francia, P. Xu, A. J. Mutsaers, D. J. Dumont, and R. S. Kerbel Cancer Res. 68(2):521-529 (2008)
to A Adenocarcinoma Adenoviridae Animals BALB Biological Burden C C57BL Cell Cells Cultured Disease Endothelial Experimental Factor Female Genetic Growth HT29 Heterologous Human Humans Inbred Male Mammary Markers Mice Neoplasm Neoplasms Progression Proliferation Prostatic Receptor-2 Research Solubility Transduction Transfection Transgenic Transplantation Tumor Tyrosine Vascular blood cells genetics metabolism methods pathology physiology protein by kanefendt on Feb 5, 2010, 11:28 AM
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Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy
J. M. Ebos, C. R. Lee, J. G. Christensen, A. J. Mutsaers, and R. S. Kerbel Proc.Natl.Acad.Sci.U.S.A 104(43):17069-17074 (2007)
to & A Administration Agents Angiogenesis Animals Antineoplastic Antitumor Assays Blood Cell Dose-Response Drug Endothelial Factor Female Growth Humans Hypoxia Indoles Inducing Line Mice Model Neoplasms Organ Outcome Placenta Pregnancy Proteins Pyrroles RANGE Receptor-2 Relationship Research Schedule Scid Specificity Treatment Tumor Tyrosine Vascular Xenograft administration blood dosage drug effects metabolism pathology pharmacology protein response therapy toxicity by kanefendt on Feb 5, 2010, 11:28 AM
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Molecular and cellular biomarkers for angiogenesis in clinical oncology
F. Bertolini, P. Mancuso, Y. Shaked, and R. S. Kerbel Drug Discov.Today 12(19-20):806-812 (2007)
to Angiogenesis Antigens Biological Cells Endothelial Humans Inhibitors Markers Microcirculation Neoplasms Neovascularization Pathologic Research Tumor blood cells diagnosis drug metabolism pathology pharmacology supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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