@article{Wang:1999:BS, title = {Surface-based {DNA} computing operations: {DESTROY} and {READOUT}}, author = {Liman Wang and Qinghua Liu and Anthony G. Frutos and Susan D. Gillmor and Andrew J. Thiel and Todd C. Strother and Anne E. Condon and Robert M. Corn and Max G. Lagally and Lloyd M. Smith}, journal = {Biosystems}, month = {October}, number = {1-3}, pages = {189--191}, volume = {52}, year = {1999}, biburl = {http://www.bibsonomy.org/bibtex/2362a8fc9f706ad1625e74157344ad642/brazovayeye}, abstract = {DNA computing on surfaces is where complex combinatorial mixtures of DNA molecules are immobilised on a substrate and subsets are tagged and enzymatically modified (DESTROY) in repeated cycles of the DNA computation. A restriction enzyme has been chosen for the surface DESTROY operation. For the READOUT operation, both cycle sequencing and PCR amplification followed by addressed array hybridisation were studied to determine the DNA sequences after the computations.}, issn = {0303-2647}, notes = { PMID: 10636044}, keywords = {Addressed Cycle PCR, Restriction algorithms, array enzyme, genetic programming, sequencing, } }