Article,

Adaptive algorithm for automatic measurement of retinal vascular diameter

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Biomedizinische Technik, 40 (11): 322--325 (1995)

Abstract

A new adaptive computer-aided method for the measurement of blood vessel diameters has been developed. Within areas of interest in the image, the algorithm detects, line-wise, the edges of the vessels, which are then used for image-wise approximation and noise filtration. A high level of adaptivity with respect to numerous measuring parameters ensures its use in a wide range of applications. Thus, it has been shown to significantly improve clinically relevant reproducibility in the area of follow-up observations. The standard deviation for vessel diameter was (2.2 +/- 0.7)\% in the case of arteries and (1.8 +/- 0.5)\% in the case of veins. Testing the algorithm in images of poor quality revealed its high level of reliability and sensitivity.

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