%0 Journal Article %1 Li2006 %A Li, Z. %A Kleinstreuer, C. %D 2006 %J Journal of Biomechanics %K AAA ANEURYSM ARTERIES DEFORMATION DIAMETER ENDOTENSION ENDOVASCULAR FIXATION FLOW FLUID-STRUCTURE FORCES INTERACTION MIGRATION MODEL PRESSURE REPAIR RUPTURE SIZE STENT-GRAFT abdominal analyses and aneurysm aneurysm-wall aortic blood computational flow interactions migration parametric sensitivity stent-graft stented stress wall %N 12 %P 2264-2273 %T Analysis of biomechanical factors affecting stent-graft migration in an abdominal aortic aneurysm model %V 39 %X Focusing on a representative abdominal aortic aneurysm (AAA) with a bifurcating stent-graft (SG), a fluid-structure interaction (FSI) solver with user-supplied programs has been employed to solve for blood flow, AAA/SG deformation, sac pressure and wall stresses, as well as the downward forces acting on the SG. Simulation results indicate that implanting a SG can significantly reduce sac pressure, mechanical stress, pulsatile wall motion, and maximum diameter change in AAAs; hence, it may restore normal blood flow and prevent AAA rupture effectively. The transient SG drag force is similar in trend as the cardiac pressure. Its magnitude depends on multi-factors including blood flow conditions, as well as SG and aneurysm geometries. Specifically, AAA neck angle, iliac bifurcation angle, neck aorta-to-iliac diameter ratio, SG size, and blood waveform play important roles in generating a fluid flow force potentially leading to SG migration. It was found that the drag force can exceed 5 N for an AAA with a large neck or iliac angle, wide aortic neck and narrow iliac arteries, large SG size, and/or abnormal blood waveform. Thus, the fixation of self-expandable or balloon-expandable SG contact may be inadequate to withstand the forces of blood flowing through the implant and hence means of extra fixation should be considered. A comprehensive FSI analysis of the coupled SG-AAA dynamics provides physical insight for evaluating the luminal hemodynamics, and maximum AAA-stresses as well as biomechanical factors leading potentially to SG migration. (c) 2005 Elsevier Ltd. All rights reserved

@article{Li2006, abstract = {Focusing on a representative abdominal aortic aneurysm (AAA) with a bifurcating stent-graft (SG), a fluid-structure interaction (FSI) solver with user-supplied programs has been employed to solve for blood flow, AAA/SG deformation, sac pressure and wall stresses, as well as the downward forces acting on the SG. Simulation results indicate that implanting a SG can significantly reduce sac pressure, mechanical stress, pulsatile wall motion, and maximum diameter change in AAAs; hence, it may restore normal blood flow and prevent AAA rupture effectively. The transient SG drag force is similar in trend as the cardiac pressure. Its magnitude depends on multi-factors including blood flow conditions, as well as SG and aneurysm geometries. Specifically, AAA neck angle, iliac bifurcation angle, neck aorta-to-iliac diameter ratio, SG size, and blood waveform play important roles in generating a fluid flow force potentially leading to SG migration. It was found that the drag force can exceed 5 N for an AAA with a large neck or iliac angle, wide aortic neck and narrow iliac arteries, large SG size, and/or abnormal blood waveform. Thus, the fixation of self-expandable or balloon-expandable SG contact may be inadequate to withstand the forces of blood flowing through the implant and hence means of extra fixation should be considered. A comprehensive FSI analysis of the coupled SG-AAA dynamics provides physical insight for evaluating the luminal hemodynamics, and maximum AAA-stresses as well as biomechanical factors leading potentially to SG migration. (c) 2005 Elsevier Ltd. All rights reserved}, added-at = {2011-03-11T12:21:24.000+0100}, author = {Li, Z. and Kleinstreuer, C.}, biburl = {https://www.bibsonomy.org/bibtex/28df041417ea267398c318deecb1abfd7/jmaiora}, interhash = {1419a4bb29ee5fb7b8e34c4f548d9266}, intrahash = {8df041417ea267398c318deecb1abfd7}, journal = {Journal of Biomechanics}, keywords = {AAA ANEURYSM ARTERIES DEFORMATION DIAMETER ENDOTENSION ENDOVASCULAR FIXATION FLOW FLUID-STRUCTURE FORCES INTERACTION MIGRATION MODEL PRESSURE REPAIR RUPTURE SIZE STENT-GRAFT abdominal analyses and aneurysm aneurysm-wall aortic blood computational flow interactions migration parametric sensitivity stent-graft stented stress wall}, number = 12, pages = {2264-2273}, timestamp = {2011-03-11T12:21:26.000+0100}, title = {Analysis of biomechanical factors affecting stent-graft migration in an abdominal aortic aneurysm model}, volume = 39, year = 2006 }