%0 Journal Article %1 schneider_vim-15_2008 %A Schneider, Ines %A Keuleyan, Emma %A Rasshofer, Rudolf %A Markovska, Rumyana %A Queenan, Anne Marie %A Bauernfeind, Adolf %D 2008 %J Antimicrobial Agents and Chemotherapy %K Acid Amino Analysis, Bacterial Bulgaria, Catalysis, Data, Germany, Hydrolysis, Isoenzymes, Kinetics, Microbial Molecular Proteins, Pseudomonas Sensitivity Sequence Substitution, Tests, aeruginosa, {DNA} {beta-Lactamases,} %N 8 %P 2977--2979 %R 10.1128/AAC.00175-08 %T VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany %U http://www.ncbi.nlm.nih.gov/pubmed/18519714 %V 52 %X Two Pseudomonas aeruginosa urine isolates from Bulgaria and Germany produced two new VIM-2 variants. VIM-15 had one amino acid substitution (Tyr218Phe) which caused a significant increase in hydrolytic efficiency. The substitution Ser54Leu, characterizing VIM-16, showed no influence on enzyme activity. Both genes were part of class I integrons located in the chromosome.

@article{schneider_vim-15_2008, abstract = {Two Pseudomonas aeruginosa urine isolates from Bulgaria and Germany produced two new {VIM-2} variants. {VIM-15} had one amino acid substitution {(Tyr218Phe)} which caused a significant increase in hydrolytic efficiency. The substitution {Ser54Leu,} characterizing {VIM-16,} showed no influence on enzyme activity. Both genes were part of class I integrons located in the chromosome.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {Schneider, Ines and Keuleyan, Emma and Rasshofer, Rudolf and Markovska, Rumyana and Queenan, Anne Marie and Bauernfeind, Adolf}, biburl = {https://www.bibsonomy.org/bibtex/25da0b245dec18c7072d94bbf91775a6d/jelias}, doi = {10.1128/AAC.00175-08}, interhash = {2a002b54f61b875279414531ce1319b7}, intrahash = {5da0b245dec18c7072d94bbf91775a6d}, issn = {1098-6596}, journal = {Antimicrobial Agents and Chemotherapy}, keywords = {Acid Amino Analysis, Bacterial Bulgaria, Catalysis, Data, Germany, Hydrolysis, Isoenzymes, Kinetics, Microbial Molecular Proteins, Pseudomonas Sensitivity Sequence Substitution, Tests, aeruginosa, {DNA} {beta-Lactamases,}}, month = aug, note = {{PMID:} 18519714}, number = 8, pages = {2977--2979}, timestamp = {2011-03-11T10:06:29.000+0100}, title = {{VIM-15} and {VIM-16,} two new {VIM-2-like} metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany}, url = {http://www.ncbi.nlm.nih.gov/pubmed/18519714}, volume = 52, year = 2008 }