%0 Journal Article %1 Houle:2010:Nat-Rev-Genet:21085204 %A Houle, D %A Govindaraju, D R %A Omholt, S %D 2010 %J Nat Rev Genet %K genotype-phenotype-map high_troughput-phenotyping phenomics phenotyping-bottleneck pleiotropy toread %N 12 %P 855-866 %R 10.1038/nrg2897 %T Phenomics: the next challenge %U https://www.ncbi.nlm.nih.gov/pubmed/21085204 %V 11 %X A key goal of biology is to understand phenotypic characteristics, such as health, disease and evolutionary fitness. Phenotypic variation is produced through a complex web of interactions between genotype and environment, and such a 'genotype-phenotype' map is inaccessible without the detailed phenotypic data that allow these interactions to be studied. Despite this need, our ability to characterize phenomes - the full set of phenotypes of an individual - lags behind our ability to characterize genomes. Phenomics should be recognized and pursued as an independent discipline to enable the development and adoption of high-throughput and high-dimensional phenotyping.

@article{Houle:2010:Nat-Rev-Genet:21085204, abstract = {A key goal of biology is to understand phenotypic characteristics, such as health, disease and evolutionary fitness. Phenotypic variation is produced through a complex web of interactions between genotype and environment, and such a 'genotype-phenotype' map is inaccessible without the detailed phenotypic data that allow these interactions to be studied. Despite this need, our ability to characterize phenomes - the full set of phenotypes of an individual - lags behind our ability to characterize genomes. Phenomics should be recognized and pursued as an independent discipline to enable the development and adoption of high-throughput and high-dimensional phenotyping.}, added-at = {2012-04-26T09:52:27.000+0200}, author = {Houle, D and Govindaraju, D R and Omholt, S}, biburl = {https://www.bibsonomy.org/bibtex/2286e0b8b68405615f3e71e10b2804248/schmidt2}, description = {Phenomics: the next challenge. [Nat Rev Genet. 2010] - PubMed - NCBI}, doi = {10.1038/nrg2897}, interhash = {a47a0336b7fcc8b9fdd4fd72b53ffa76}, intrahash = {286e0b8b68405615f3e71e10b2804248}, journal = {Nat Rev Genet}, keywords = {genotype-phenotype-map high_troughput-phenotyping phenomics phenotyping-bottleneck pleiotropy toread}, month = dec, number = 12, pages = {855-866}, pmid = {21085204}, timestamp = {2012-04-26T09:53:54.000+0200}, title = {Phenomics: the next challenge}, url = {https://www.ncbi.nlm.nih.gov/pubmed/21085204}, volume = 11, year = 2010 }