Article,
How to flip the (redox) switch
Cell, 111 (5): 607-610 (November 2002)
Abstract
Redox-sensitive transcription factors such as the E. coli OxyR and S. cerevisiae Yap1, are activated by conformational changes that stem from the post-translational modification of reactive protein thiols. Recent studies provide new insights on how different agents that cause redox stress mediate the activation of transcription through distinct and specific pathways.
