Article,
Junctions in inbreeding
Genetica, 26 (5-6): 392-406 (1953)
Abstract
For a regular system of inbreeding, the genetic consequences
of primary importance are embodied in the generation matrix which
may be constructed for matings relative to a single locus. In con-
sidering the heterogeneity of the germ plasm, the initial state at
each locus may be taken to be that of greatest complexity. It follows
that if the probability of a mating being heterogeneous at any locus
in a given generation is p and is the same for all loci, then for k loci,
with any linkage relations, the expected number in the heterogeneous
condition is kp. However, closely linked loci are more likely to be
in the same state, either heterogeneous or homogeneous, than loci
showing loose linkage and it is of some little interest to consider
the number and typical length of the separate heterogeneous tracts
after many generations. Such a discussion has been given for
the sib-mating of disomic organisms by FISHER (I949). As the
approach through junctions constitutes an important advance in
inbreeding theory, further discussions of the method seem desirable.
