Article,

Blocking them all: beta-arrestins inhibit cellular signaling

, and .
Mol Cell, 31 (5): 619-21 (September 2008)Lohse, Martin J Klenk, Christoph Comment United States Molecular cell Mol Cell. 2008 Sep 5;31(5):619-21..

Abstract

beta-arrestins are scaffold proteins that link G protein-coupled receptors to multiple "nonclassical" signaling pathways. In this issue of Molecular Cell, Mo et al. (2008) show that beta-arrestin1 also switches off signaling through the STAT1 transcription factor, thereby inhibiting interferon-induced antiviral responses.

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