%0 Journal Article %1 Nisenblat2006 %A Nisenblat, Vicki %A Alon, Eran %A Barak, Shlomi %A Gonen, Ron %A Bader, David %A Ohel, Gonen %D 2006 %J Acta Obstet Gynecol Scand %K Cerebral Palsy; Child, Preschool; Developmental Disabilities; Female; Fetal Monitoring; Heart Rate, Fetal; Humans; Infant, Newborn; Very Low Birth Weight; Labor, Obstetric; Male; Predictive Value of Tests; Pregnancy; Sensitivity and Specificity %N 7 %P 792--796 %R 10.1080/00016340500501707 %T Fetal heart rate patterns and neurodevelopmental outcome in very low birth weight infants. %U http://dx.doi.org/10.1080/00016340500501707 %V 85 %X BACKGROUND: To evaluate the validity of fetal heart rate monitoring during the last hour prior to birth, as a predictor of long term neurodevelopmental outcome of very low birth weight infants. METHODS: A total of 111 very low birth weight infants were included in the study. Fetal heart rate tracings were obtained during the last hour prior to delivery. A perinatologist, blinded to the neonatal outcome, evaluated the tracings and divided them into three groups: reassuring, nonreassuring, and pathological. Neurodevelopmental status was evaluated at age 2 years. The relationship between fetal heart rate monitoring results and the neurodevelopmental outcome at 2 years of age was assessed with a chi-square test and the Student's t-test. RESULTS: At 2 years of age 97 (87.4\%) of the children had normal neurodevelopmental function, while 14 (12.6\%) had variable degrees of neurodevelopmental impairment. The fetal heart rate monitoring results were classified as reassuring (normal) in 35 cases (31.5\%), nonreassuring in 56 cases (50.5\%), and pathological in 20 cases (18.0\%). Both normal and pathological fetal heart rate patterns were associated with similar incidence of abnormal neurodevelopmental outcome, 14.3\% and 15.0\% of cases, respectively (p=0.778). Pathological fetal heart rate patterns as a predictor of neurodevelopmental outcome had a sensitivity of 27\%, specificity of 74\%, positive predictive value of 15\%, and negative predictive value of 86\%. CONCLUSION: Electronic fetal heart rate monitoring prior to delivery is not a reliable tool for the prediction of neurodevelopmental impairment in premature infants of very low birth weight, at 2 years of age.

@article{Nisenblat2006, abstract = {BACKGROUND: To evaluate the validity of fetal heart rate monitoring during the last hour prior to birth, as a predictor of long term neurodevelopmental outcome of very low birth weight infants. METHODS: A total of 111 very low birth weight infants were included in the study. Fetal heart rate tracings were obtained during the last hour prior to delivery. A perinatologist, blinded to the neonatal outcome, evaluated the tracings and divided them into three groups: reassuring, nonreassuring, and pathological. Neurodevelopmental status was evaluated at age 2 years. The relationship between fetal heart rate monitoring results and the neurodevelopmental outcome at 2 years of age was assessed with a chi-square test and the Student's t-test. RESULTS: At 2 years of age 97 (87.4\%) of the children had normal neurodevelopmental function, while 14 (12.6\%) had variable degrees of neurodevelopmental impairment. The fetal heart rate monitoring results were classified as reassuring (normal) in 35 cases (31.5\%), nonreassuring in 56 cases (50.5\%), and pathological in 20 cases (18.0\%). Both normal and pathological fetal heart rate patterns were associated with similar incidence of abnormal neurodevelopmental outcome, 14.3\% and 15.0\% of cases, respectively (p=0.778). Pathological fetal heart rate patterns as a predictor of neurodevelopmental outcome had a sensitivity of 27\%, specificity of 74\%, positive predictive value of 15\%, and negative predictive value of 86\%. CONCLUSION: Electronic fetal heart rate monitoring prior to delivery is not a reliable tool for the prediction of neurodevelopmental impairment in premature infants of very low birth weight, at 2 years of age.}, added-at = {2014-07-19T20:55:58.000+0200}, author = {Nisenblat, Vicki and Alon, Eran and Barak, Shlomi and Gonen, Ron and Bader, David and Ohel, Gonen}, biburl = {https://www.bibsonomy.org/bibtex/2b9f0f1d4e4fff2aca3bba08fc39407a3/ar0berts}, doi = {10.1080/00016340500501707}, groups = {public}, interhash = {fd98424ecd05b7a9bd794fb48a165ecc}, intrahash = {b9f0f1d4e4fff2aca3bba08fc39407a3}, journal = {Acta Obstet Gynecol Scand}, keywords = {Cerebral Palsy; Child, Preschool; Developmental Disabilities; Female; Fetal Monitoring; Heart Rate, Fetal; Humans; Infant, Newborn; Very Low Birth Weight; Labor, Obstetric; Male; Predictive Value of Tests; Pregnancy; Sensitivity and Specificity}, number = 7, pages = {792--796}, pii = {744941361}, pmid = {16817075}, timestamp = {2014-07-19T20:55:58.000+0200}, title = {Fetal heart rate patterns and neurodevelopmental outcome in very low birth weight infants.}, url = {http://dx.doi.org/10.1080/00016340500501707}, username = {ar0berts}, volume = 85, year = 2006 }