| Authors: |
M. Vigneau
and G. Jobard
and B. Mazoyer
and N. Tzourio-Mazoyer
|
| URL: |
http://dx.doi.org/10.1016/j.neuroimage.2005.04.038 |
| Tags: |
Adolescent;
Adult;
Auditory
Brain
Computer-Assisted;
Female;
Fixation,
Gov't;
Humans;
Image
Imaging;
Laterality;
Magnetic
Male;
Mapping;
Nerve
Net;
Non-U.S.
Ocular;
Oxygen;
Perception
Perception;
Processing,
Reading;
Research
Resonance
Speech;
Support,
Visual
|
| Abstract: |
The putative role of the so-called Visual Word Form Area (VWFA) during
reading remains under debate. For some authors, this region is specifically
involved in a pre-lexical processing of words and pseudowords, whereas
such specificity is challenged by others given the VWFA involvement
during both non-word reading and word listening. Here, we further
investigated this issue, measuring BOLD variations and their lateralization
with fMRI during word and non-word reading, in order to evaluate
the lexicality effect, and during reading and listening of words,
in order to evaluate the impact of stimulus delivery modality on
word processing networks. Region of interest (ROI) analysis was first
performed in three target areas: 1-VWFA as defined by a meta-analysis
of the word reading literature, 2-a middle temporal area (T2) found
co-activated by both word reading and listening, 3-an inferior occipital
area (OI) belonging to the unimodal visual cortex of the inferior
occipital gyrus. VWFA activity was found not different between word
and non-word reading but was more leftward lateralized during word
reading due to a reduction of activity in the VWFA right counterpart.
A similar larger leftward lateralization during word reading was
also uncovered in the T2 ROI but was related to a larger left side
activity. Such a lexicality effect was not observed in the OI ROI.
By contrast, BOLD increases during listening were restricted to the
left VWFA and T2 ROIs. Voxel-based analysis (SPM99) showed that semantic
areas were more active during word than non-word reading and co-activated
by both reading and listening, exhibiting a left lateralized activity
in all tasks. These results indicate that the left VWFA would be
the place where visual and verbal representations bind under the
control of left semantic areas. |
@article{Vigneau2005,
title = {Word and non-word reading: what role for the Visual Word Form Area?},
author = {M. Vigneau and G. Jobard and B. Mazoyer and N. Tzourio-Mazoyer},
journal = {Neuroimage},
pages = {694--705},
url = {http://dx.doi.org/10.1016/j.neuroimage.2005.04.038},
volume = {27},
year = {2005},
abstract = {The putative role of the so-called Visual Word Form Area (VWFA) during
reading remains under debate. For some authors, this region is specifically
involved in a pre-lexical processing of words and pseudowords, whereas
such specificity is challenged by others given the VWFA involvement
during both non-word reading and word listening. Here, we further
investigated this issue, measuring BOLD variations and their lateralization
with fMRI during word and non-word reading, in order to evaluate
the lexicality effect, and during reading and listening of words,
in order to evaluate the impact of stimulus delivery modality on
word processing networks. Region of interest (ROI) analysis was first
performed in three target areas: 1-VWFA as defined by a meta-analysis
of the word reading literature, 2-a middle temporal area (T2) found
co-activated by both word reading and listening, 3-an inferior occipital
area (OI) belonging to the unimodal visual cortex of the inferior
occipital gyrus. VWFA activity was found not different between word
and non-word reading but was more leftward lateralized during word
reading due to a reduction of activity in the VWFA right counterpart.
A similar larger leftward lateralization during word reading was
also uncovered in the T2 ROI but was related to a larger left side
activity. Such a lexicality effect was not observed in the OI ROI.
By contrast, BOLD increases during listening were restricted to the
left VWFA and T2 ROIs. Voxel-based analysis (SPM99) showed that semantic
areas were more active during word than non-word reading and co-activated
by both reading and listening, exhibiting a left lateralized activity
in all tasks. These results indicate that the left VWFA would be
the place where visual and verbal representations bind under the
control of left semantic areas.},
pii = {S1053-8119(05)00282-X}, doi = {10.1016/j.neuroimage.2005.04.038}, pmid = {15961322},
keywords = {Adolescent; Adult; Auditory Brain Computer-Assisted; Female; Fixation, Gov't; Humans; Image Imaging; Laterality; Magnetic Male; Mapping; Nerve Net; Non-U.S. Ocular; Oxygen; Perception Perception; Processing, Reading; Research Resonance Speech; Support, Visual }
}
::