OBJECTIVE: To assess the neurodevelopmental outcome of infants born at 24-26 weeks' gestation. METHODS: One hundred thirty-eight nonanomalous infants were born at our hospital after pregnancies of 24-26 weeks' gestation between 1990 and 1994. Ninety-four infants survived to discharge and 86 were followed in a nursery follow-up program for outcome. Associations between gestational age and neurodevelopmental outcome and risk factors and outcome were analyzed. Mean age at follow-up was 32 months. RESULTS: The frequency of cerebral palsy did not differ significantly in the three groups (11, 20, and 11\% at 24, 25, and 26 weeks, respectively). The incidence of normal cognitive outcome was associated significantly with gestational age at birth (28, 47, and 71\% normal at 24, 25, and 26 weeks, respectively). Poor neurologic outcome was associated with the medical risk factor of intracranial hemorrhage grade 3 or 4 or periventricular leukomalacia. Poor cognitive outcome was correlated with both medical and social risk factors; however, there was an association between poor cognitive outcome and lower gestational age (P < .05), regardless of the relationships of any other risk factors to cognitive outcome. CONCLUSION: Although the incidence of cerebral palsy was low in these three groups, the high percentage of infants born at 24 and 25 weeks' gestation with cognitive deficits is concerning.
%0 Journal Article
%1 Piecuch1997
%A Piecuch, R. E.
%A Leonard, C. H.
%A Cooper, B. A.
%A Kilpatrick, S. J.
%A Schlueter, M. A.
%A Sola, A.
%D 1997
%J Obstet Gynecol
%K Cerebral Palsy; Child, Preschool; Cohort Studies; Developmental Disabilities; Female; Follow-Up Gestational Age; Humans; Incidence; Infant, Newborn; Premature; Male; Pregnancy; Retrospective Risk Fact; ors
%N 5
%P 809--814
%R 10.1016/S0029-7844(97)00429-8
%T Outcome of infants born at 24-26 weeks' gestation: II. Neurodevelopmental outcome.
%U http://dx.doi.org/10.1016/S0029-7844(97)00429-8
%V 90
%X OBJECTIVE: To assess the neurodevelopmental outcome of infants born at 24-26 weeks' gestation. METHODS: One hundred thirty-eight nonanomalous infants were born at our hospital after pregnancies of 24-26 weeks' gestation between 1990 and 1994. Ninety-four infants survived to discharge and 86 were followed in a nursery follow-up program for outcome. Associations between gestational age and neurodevelopmental outcome and risk factors and outcome were analyzed. Mean age at follow-up was 32 months. RESULTS: The frequency of cerebral palsy did not differ significantly in the three groups (11, 20, and 11\% at 24, 25, and 26 weeks, respectively). The incidence of normal cognitive outcome was associated significantly with gestational age at birth (28, 47, and 71\% normal at 24, 25, and 26 weeks, respectively). Poor neurologic outcome was associated with the medical risk factor of intracranial hemorrhage grade 3 or 4 or periventricular leukomalacia. Poor cognitive outcome was correlated with both medical and social risk factors; however, there was an association between poor cognitive outcome and lower gestational age (P < .05), regardless of the relationships of any other risk factors to cognitive outcome. CONCLUSION: Although the incidence of cerebral palsy was low in these three groups, the high percentage of infants born at 24 and 25 weeks' gestation with cognitive deficits is concerning.
@article{Piecuch1997,
abstract = {OBJECTIVE: To assess the neurodevelopmental outcome of infants born at 24-26 weeks' gestation. METHODS: One hundred thirty-eight nonanomalous infants were born at our hospital after pregnancies of 24-26 weeks' gestation between 1990 and 1994. Ninety-four infants survived to discharge and 86 were followed in a nursery follow-up program for outcome. Associations between gestational age and neurodevelopmental outcome and risk factors and outcome were analyzed. Mean age at follow-up was 32 months. RESULTS: The frequency of cerebral palsy did not differ significantly in the three groups (11, 20, and 11\% at 24, 25, and 26 weeks, respectively). The incidence of normal cognitive outcome was associated significantly with gestational age at birth (28, 47, and 71\% normal at 24, 25, and 26 weeks, respectively). Poor neurologic outcome was associated with the medical risk factor of intracranial hemorrhage grade 3 or 4 or periventricular leukomalacia. Poor cognitive outcome was correlated with both medical and social risk factors; however, there was an association between poor cognitive outcome and lower gestational age (P < .05), regardless of the relationships of any other risk factors to cognitive outcome. CONCLUSION: Although the incidence of cerebral palsy was low in these three groups, the high percentage of infants born at 24 and 25 weeks' gestation with cognitive deficits is concerning.},
added-at = {2014-07-19T21:02:25.000+0200},
author = {Piecuch, R. E. and Leonard, C. H. and Cooper, B. A. and Kilpatrick, S. J. and Schlueter, M. A. and Sola, A.},
biburl = {https://www.bibsonomy.org/bibtex/246f38b83fdc3443544fd71fee3d544d2/ar0berts},
doi = {10.1016/S0029-7844(97)00429-8},
groups = {public},
interhash = {6285cfa14d306721831dcac2333a2401},
intrahash = {46f38b83fdc3443544fd71fee3d544d2},
journal = {Obstet Gynecol},
keywords = {Cerebral Palsy; Child, Preschool; Cohort Studies; Developmental Disabilities; Female; Follow-Up Gestational Age; Humans; Incidence; Infant, Newborn; Premature; Male; Pregnancy; Retrospective Risk Fact; ors},
month = Nov,
number = 5,
pages = {809--814},
pii = {S0029-7844(97)00429-8},
pmid = {9351769},
timestamp = {2014-07-19T21:02:25.000+0200},
title = {Outcome of infants born at 24-26 weeks' gestation: II. Neurodevelopmental outcome.},
url = {http://dx.doi.org/10.1016/S0029-7844(97)00429-8},
username = {ar0berts},
volume = 90,
year = 1997
}