Abstract

Physical Biology of the Cell is a biophysics textbook that explores how the basic tools and insights of physics and mathematics can illuminate the study of molecular and cell biology. Drawing on key examples and seminal experiments from cell biology, the book demonstrates how quantitative models can help refine our understanding of existing biological data and also be used to make useful predictions. The book blends traditional models in cell biology with the quantitative approach typical in physics, in order to introduce the reader to both the possibilities and boundaries of the emerging field of physical biology. While teaching physical model building in cell biology through a practical, case-study approach, the text explores how quantitative modeling can be used to build a more profound, intuitive understanding of cell biology.

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