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Confirmation of region-specific patterns of gene expression in the human brain

by: Carl Ernst, Adolfo Sequeira, Tim Klempan, Neil Ernst, Jarlath ffrench Mullen, and Gustavo Turecki

In: Neurogenetics, Vol. 8, Nr. 3 (August 2007) , p. 219--224.

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URL:	http://dx.doi.org/10.1007/s10048-007-0084-2

The human brain is divided and categorized in different ways, yet a molecular genetic approach to region specificity does not exist. Using data from 12 healthy control subjects across 18 brain regions, we performed a microarray analysis using boththe HG-U133AB and HG-U133 plus 2 chips for each subject to determine molecular targets showing region specificity. Using apreviously published data as our guide, we confirm SIX3, GPR6, SH3RF2, and hSyn as molecular markers of the nucleus accumbensand gamma-aminobutyric-acid A receptor alpha-6, Nik-related kinase, and eomesodermin as molecular markers of the cerebellum.

BibTeX record

@article{ernst07neuro,
  abstract = {The human brain is divided and categorized in different ways, yet a molecular genetic approach to region specificity does
not exist. Using data from 12 healthy control subjects across 18 brain regions, we performed a microarray analysis using boththe HG-U133AB and HG-U133 plus 2 chips for each subject to determine molecular targets showing region specificity. Using apreviously published data as our guide, we confirm SIX3, GPR6, SH3RF2, and hSyn as molecular markers of the nucleus accumbensand gamma-aminobutyric-acid A receptor alpha-6, Nik-related kinase, and eomesodermin as molecular markers of the cerebellum.},
  added-at = {2008-01-16T02:57:01.000+0100},
  author = {Ernst, Carl and Sequeira, Adolfo and Klempan, Tim and Ernst, Neil and ffrench Mullen, Jarlath and Turecki, Gustavo},
  biburl = {http://www.bibsonomy.org/bibtex/2719b15632c8a56577b34e2bfaa5869aa/neilernst},
  interhash = {871dea5cab0bab9f1464a147f8772f03},
  intrahash = {719b15632c8a56577b34e2bfaa5869aa},
  journal = {Neurogenetics},
  keywords = {neuroscience personal},
  month = {#aug#},
  number = 3,
  pages = {219--224},
  timestamp = {2008-01-16T02:57:01.000+0100},
  title = {Confirmation of region-specific patterns of gene expression in the human brain},
  url = {http://dx.doi.org/10.1007/s10048-007-0084-2},
  volume = 8,
  year = 2007
}

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BibSonomy :: publication ::

Confirmation of region-specific patterns of gene expression in the human brain

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