%0 Journal Article %1 Kitchen1986 %A Kitchen, W. H. %A Rickards, A. L. %A Ryan, M. M. %A Ford, G. W. %A Lissenden, J. V. %A Boyle, L. W. %D 1986 %J Dev Med Child Neurol %K Cerebral Palsy; Child Development; Child, Preschool; Disabled Persons; Humans; Infant, Low Birth Weight; Newborn; Intelligence; Mortality; Prognosis; Prospective Studies; Risk; Socioeconomic Factors %N 5 %P 579--588 %T Improved outcome to two years of very low-birthweight infants: fact or artifact? %V 28 %X In 1966-70, the survival rate for very low-birthweight (VLBW) children born in a tertiary perinatal centre was 37.1 per cent but by 1980-82 it had increased to 68.3 per cent. The latter cohort had a significantly reduced prevalence of strabismus, myopia and a head circumference under the 10th percentile, but a significantly increased prevalence of cerebral palsy compared with the 1966-70 VLBW children. Survivors born in 1980-82 had a significantly increased mean Mental Development Index (MDI) on the Bayley Scales compared with the sub-group of survivors born in 1968-70 but there was also a significant improvement in mean MDI over time for a group of normal-birthweight children. No improvement of MDI scores of VLBW survivors in the 1980-82 cohort could be attributed solely to perinatal care. The two-year-old VLBW children in the 1980-82 cohort had similar rates of sensorineural impairments, disabilities and mean MDI to those who would have survived with the care available in 1966-70. It is concluded that survival of VLBW infants has improved in recent times but that neurodevelopmental outcome still lags behind that of normal-birthweight peers.

@article{Kitchen1986, abstract = {In 1966-70, the survival rate for very low-birthweight (VLBW) children born in a tertiary perinatal centre was 37.1 per cent but by 1980-82 it had increased to 68.3 per cent. The latter cohort had a significantly reduced prevalence of strabismus, myopia and a head circumference under the 10th percentile, but a significantly increased prevalence of cerebral palsy compared with the 1966-70 VLBW children. Survivors born in 1980-82 had a significantly increased mean Mental Development Index (MDI) on the Bayley Scales compared with the sub-group of survivors born in 1968-70 but there was also a significant improvement in mean MDI over time for a group of normal-birthweight children. No improvement of MDI scores of VLBW survivors in the 1980-82 cohort could be attributed solely to perinatal care. The two-year-old VLBW children in the 1980-82 cohort had similar rates of sensorineural impairments, disabilities and mean MDI to those who would have survived with the care available in 1966-70. It is concluded that survival of VLBW infants has improved in recent times but that neurodevelopmental outcome still lags behind that of normal-birthweight peers.}, added-at = {2014-07-19T20:38:10.000+0200}, author = {Kitchen, W. H. and Rickards, A. L. and Ryan, M. M. and Ford, G. W. and Lissenden, J. V. and Boyle, L. W.}, biburl = {https://www.bibsonomy.org/bibtex/275d5bc1f5cb3ab57902423ebb5052a6c/ar0berts}, groups = {public}, interhash = {58a36399a64f0914b1225e5582063a71}, intrahash = {75d5bc1f5cb3ab57902423ebb5052a6c}, journal = {Dev Med Child Neurol}, keywords = {Cerebral Palsy; Child Development; Child, Preschool; Disabled Persons; Humans; Infant, Low Birth Weight; Newborn; Intelligence; Mortality; Prognosis; Prospective Studies; Risk; Socioeconomic Factors}, month = Oct, number = 5, pages = {579--588}, pmid = {2946619}, timestamp = {2014-07-19T20:38:10.000+0200}, title = {Improved outcome to two years of very low-birthweight infants: fact or artifact?}, username = {ar0berts}, volume = 28, year = 1986 }