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A systems-level integrative framework from genome-wide DNA methylation and gene expression data identifies differential gene expression modules under epigenetic control

, , and . Bioinformatics 30 (16): 2360-2366 (May 2014)


This article discusses Functional Epigenetic Modules (FEM), which are used to study gene expression in studies of DNA methylation. Teschendorff et al. used this algorithm to identify important signalling pathways in their breast cancer dataset.

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