The toughness of cortical bone and its relationship with age.
X. Wang, and S. Puram. Ann Biomed Eng, 32 (1):
123--135(January 2004)
Abstract
Toughness is a quantitative measure of bone quality in terms of its susceptibility to fracture. Thus, to elucidate the underlying mechanisms of age-related bone fractures, it is necessary to understand age-related changes in the toughness of bone. The objective of this review is to provide current understanding on the structure-function relationships of cortical bone and its correlation with the toughness of the tissue from the perspective of basic engineering principles. The review is written for the readers in the musculoskeletal research field, who may not have a strong engineering background. For better understanding of toughening mechanisms, this review intends to focus on correlations of the toughness of cortical bone with its constituents and microstructural characteristics. In addition, a special emphasis is placed on age-related changes in the toughness of bone.
%0 Journal Article
%1 Wang2004
%A Wang, Xiaodu
%A Puram, Sreekar
%D 2004
%J Ann Biomed Eng
%K Aging physiology Animals BoneDensity BoneandBones Collagen CompressiveStrength Elasticity Fractures Bone physiopathology Hardness Humans Porosity Stress Mechanical
%N 1
%P 123--135
%T The toughness of cortical bone and its relationship with age.
%V 32
%X Toughness is a quantitative measure of bone quality in terms of its susceptibility to fracture. Thus, to elucidate the underlying mechanisms of age-related bone fractures, it is necessary to understand age-related changes in the toughness of bone. The objective of this review is to provide current understanding on the structure-function relationships of cortical bone and its correlation with the toughness of the tissue from the perspective of basic engineering principles. The review is written for the readers in the musculoskeletal research field, who may not have a strong engineering background. For better understanding of toughening mechanisms, this review intends to focus on correlations of the toughness of cortical bone with its constituents and microstructural characteristics. In addition, a special emphasis is placed on age-related changes in the toughness of bone.
@article{Wang2004,
abstract = {Toughness is a quantitative measure of bone quality in terms of its susceptibility to fracture. Thus, to elucidate the underlying mechanisms of age-related bone fractures, it is necessary to understand age-related changes in the toughness of bone. The objective of this review is to provide current understanding on the structure-function relationships of cortical bone and its correlation with the toughness of the tissue from the perspective of basic engineering principles. The review is written for the readers in the musculoskeletal research field, who may not have a strong engineering background. For better understanding of toughening mechanisms, this review intends to focus on correlations of the toughness of cortical bone with its constituents and microstructural characteristics. In addition, a special emphasis is placed on age-related changes in the toughness of bone.},
added-at = {2012-01-13T14:18:55.000+0100},
author = {Wang, Xiaodu and Puram, Sreekar},
biburl = {https://www.bibsonomy.org/bibtex/2cc1ad09cb77fe79b373aededd7494be2/bunke},
file = {:_BIBUS_toughness_bone_preview.pdf:PDF},
groups = {public},
institution = {Department of Mechanical Engineering and Biomechanics, The University of Texas at San Antonio, San Antonio, TX 78249-0670, USA. xwang@utsa.edu},
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intrahash = {cc1ad09cb77fe79b373aededd7494be2},
journal = {Ann Biomed Eng},
keywords = {Aging physiology Animals BoneDensity BoneandBones Collagen CompressiveStrength Elasticity Fractures Bone physiopathology Hardness Humans Porosity Stress Mechanical},
month = Jan,
number = 1,
pages = {123--135},
pmid = {14964728},
timestamp = {2012-01-13T16:35:30.000+0100},
title = {The toughness of cortical bone and its relationship with age.},
username = {bunke},
volume = 32,
year = 2004
}