The venous oxygen saturation reflects pathophysiological changes in oxygen delivery and consumption, where the saturation range beneath 50% may represent a clinical borderline to avoid irreversible damage. We present a model to simulate a desaturation investigation with 4 plateaus (PL 1 = 99 ± 0.3%; PL 2 = 75 ± 3%; PL 3 = 50 ± 3%, PL 4 = 25 ± 3%). A continuous wave multi-distance near-infrared spectroscopy sensor (wavelengths: 770, 808 and 850 nm; 6 photodiodes (PD 1−6 ), linearly arranged, separated 6 mm each) was equipped to detect the saturation at these plateaus. The study was divided in 5 calibration experiments (1 day; 5 per day) and 25 experiments (5 days; 5 per day) with the calibrated sensor unit. The detected saturation was compared with the reference values from the CO-Oximetry unit (IL-682) while keeping the amount of total hemoglobin (tHb) and the other physiological parameters at constant levels (tHb = 12 ± 0.3 g dl −1 , blood temperature = 35.5 ± 0.6 °C, carbon dioxide partial pressure (pCO 2 ) = 39 ± 6 mmHg, glucose = 103 ± 9 mg dl −1 and pH 7.4 ± 0.04). The oxygen saturation, in the range from 99% to 20%, could be detected reproducible with a mean absolute deviation of 3%.
%0 Journal Article
%1 2057-1976-2-3-035017
%A Rackebrandt, K
%A Gehring, H
%D 2016
%J Biomedical Physics & Engineering Express
%K RackebrandtKlaas imt
%N 3
%P 035017
%T Calibration and evaluation of a continuous wave multi-distance NIRS system in simulated desaturation investigations
%U http://stacks.iop.org/2057-1976/2/i=3/a=035017
%V 2
%X The venous oxygen saturation reflects pathophysiological changes in oxygen delivery and consumption, where the saturation range beneath 50% may represent a clinical borderline to avoid irreversible damage. We present a model to simulate a desaturation investigation with 4 plateaus (PL 1 = 99 ± 0.3%; PL 2 = 75 ± 3%; PL 3 = 50 ± 3%, PL 4 = 25 ± 3%). A continuous wave multi-distance near-infrared spectroscopy sensor (wavelengths: 770, 808 and 850 nm; 6 photodiodes (PD 1−6 ), linearly arranged, separated 6 mm each) was equipped to detect the saturation at these plateaus. The study was divided in 5 calibration experiments (1 day; 5 per day) and 25 experiments (5 days; 5 per day) with the calibrated sensor unit. The detected saturation was compared with the reference values from the CO-Oximetry unit (IL-682) while keeping the amount of total hemoglobin (tHb) and the other physiological parameters at constant levels (tHb = 12 ± 0.3 g dl −1 , blood temperature = 35.5 ± 0.6 °C, carbon dioxide partial pressure (pCO 2 ) = 39 ± 6 mmHg, glucose = 103 ± 9 mg dl −1 and pH 7.4 ± 0.04). The oxygen saturation, in the range from 99% to 20%, could be detected reproducible with a mean absolute deviation of 3%.
@article{2057-1976-2-3-035017,
abstract = {The venous oxygen saturation reflects pathophysiological changes in oxygen delivery and consumption, where the saturation range beneath 50% may represent a clinical borderline to avoid irreversible damage. We present a model to simulate a desaturation investigation with 4 plateaus (PL 1 = 99 ± 0.3%; PL 2 = 75 ± 3%; PL 3 = 50 ± 3%, PL 4 = 25 ± 3%). A continuous wave multi-distance near-infrared spectroscopy sensor (wavelengths: 770, 808 and 850 nm; 6 photodiodes (PD 1−6 ), linearly arranged, separated 6 mm each) was equipped to detect the saturation at these plateaus. The study was divided in 5 calibration experiments (1 day; 5 per day) and 25 experiments (5 days; 5 per day) with the calibrated sensor unit. The detected saturation was compared with the reference values from the CO-Oximetry unit (IL-682) while keeping the amount of total hemoglobin (tHb) and the other physiological parameters at constant levels (tHb = 12 ± 0.3 g dl −1 , blood temperature = 35.5 ± 0.6 °C, carbon dioxide partial pressure (pCO 2 ) = 39 ± 6 mmHg, glucose = 103 ± 9 mg dl −1 and pH 7.4 ± 0.04). The oxygen saturation, in the range from 99% to 20%, could be detected reproducible with a mean absolute deviation of 3%.},
added-at = {2016-07-08T09:50:04.000+0200},
author = {Rackebrandt, K and Gehring, H},
biburl = {https://www.bibsonomy.org/bibtex/2d946c41dda514557fcc6162580b56a08/imt_bibsonomy},
interhash = {c6c860c381bd67edfca039752ebbc8fa},
intrahash = {d946c41dda514557fcc6162580b56a08},
journal = {Biomedical Physics & Engineering Express},
keywords = {RackebrandtKlaas imt},
number = 3,
pages = 035017,
timestamp = {2016-07-08T09:50:04.000+0200},
title = {Calibration and evaluation of a continuous wave multi-distance NIRS system in simulated desaturation investigations},
url = {http://stacks.iop.org/2057-1976/2/i=3/a=035017},
volume = 2,
year = 2016
}