Adductor spasticity in children with cerebral palsy (CP) impairs motor function and development. In a placebo-controlled, double-blind, randomized multicentre study, we evaluated the effects of botulinum toxin A(BTX-A) in 61 children (37 males, 24 females; mean age 6 years 1 month SD 3y 1mo) with CP (leg-dominated tetraparesis, n=39; tetraparesis, n=22; GMFCS level I, n=3; II, n=6; III, n=17; IV, n=29; V, n=6). Four weeks after treatment, a significant superiority of BTX-A was observed in the primary outcome measure (knee-knee distance 'fast catch', p=0.002), the Ashworth scale (p=0.001), and the Goal Attainment Scale (p=0.037).
%0 Journal Article
%1 Mall2006
%A Mall, Volker
%A Heinen, Florian
%A Siebel, Andrea
%A Bertram, Christoph
%A Hafkemeyer, Ulrich
%A Wissel, J?rg
%A Berweck, Steffen
%A Haverkamp, Fritz
%A Nass, G?nter
%A D?derlein, Leo
%A Breitbach-Faller, Nico
%A Schulte-Mattler, Wilhelm
%A Korinthenberg, Rudolf
%D 2006
%J Dev Med Child Neurol
%K Botulinum Toxin Type A; Cerebral Palsy; Child; Child, Preschool; Double-Blind Method; Female; Hip Joint; Humans; Knee Male; Muscle Spasticity; Neuromuscular Agents; Placebos; Treatment Outcome
%N 1
%P 10--13
%R 10.1017/S0012162206000041
%T Treatment of adductor spasticity with BTX-A in children with CP: a randomized, double-blind, placebo-controlled study.
%U http://dx.doi.org/10.1017/S0012162206000041
%V 48
%X Adductor spasticity in children with cerebral palsy (CP) impairs motor function and development. In a placebo-controlled, double-blind, randomized multicentre study, we evaluated the effects of botulinum toxin A(BTX-A) in 61 children (37 males, 24 females; mean age 6 years 1 month SD 3y 1mo) with CP (leg-dominated tetraparesis, n=39; tetraparesis, n=22; GMFCS level I, n=3; II, n=6; III, n=17; IV, n=29; V, n=6). Four weeks after treatment, a significant superiority of BTX-A was observed in the primary outcome measure (knee-knee distance 'fast catch', p=0.002), the Ashworth scale (p=0.001), and the Goal Attainment Scale (p=0.037).
@article{Mall2006,
abstract = {Adductor spasticity in children with cerebral palsy (CP) impairs motor function and development. In a placebo-controlled, double-blind, randomized multicentre study, we evaluated the effects of botulinum toxin A(BTX-A) in 61 children (37 males, 24 females; mean age 6 years 1 month [SD 3y 1mo]) with CP (leg-dominated tetraparesis, n=39; tetraparesis, n=22; GMFCS level I, n=3; II, n=6; III, n=17; IV, n=29; V, n=6). Four weeks after treatment, a significant superiority of BTX-A was observed in the primary outcome measure (knee-knee distance 'fast catch', p=0.002), the Ashworth scale (p=0.001), and the Goal Attainment Scale (p=0.037).},
added-at = {2014-07-19T20:45:14.000+0200},
author = {Mall, Volker and Heinen, Florian and Siebel, Andrea and Bertram, Christoph and Hafkemeyer, Ulrich and Wissel, J?rg and Berweck, Steffen and Haverkamp, Fritz and Nass, G?nter and D?derlein, Leo and Breitbach-Faller, Nico and Schulte-Mattler, Wilhelm and Korinthenberg, Rudolf},
biburl = {https://www.bibsonomy.org/bibtex/2fd26cc61a2cf50579626e063ff93493e/ar0berts},
doi = {10.1017/S0012162206000041},
groups = {public},
interhash = {5d3f95f65969d23c7a41c7ffb39c4e1e},
intrahash = {fd26cc61a2cf50579626e063ff93493e},
journal = {Dev Med Child Neurol},
keywords = {Botulinum Toxin Type A; Cerebral Palsy; Child; Child, Preschool; Double-Blind Method; Female; Hip Joint; Humans; Knee Male; Muscle Spasticity; Neuromuscular Agents; Placebos; Treatment Outcome},
month = Jan,
number = 1,
pages = {10--13},
pii = {S0012162206000041},
pmid = {16359588},
timestamp = {2014-07-19T20:45:14.000+0200},
title = {Treatment of adductor spasticity with BTX-A in children with CP: a randomized, double-blind, placebo-controlled study.},
url = {http://dx.doi.org/10.1017/S0012162206000041},
username = {ar0berts},
volume = 48,
year = 2006
}