BibSonomy :: publication ::

tag user group author concept BibTeX key search:all search:ebo

The blue social bookmark and publication sharing system.

entry of ebo:

(0)

This publication has not been reviewed yet.

rating distribution

average user rating

The average rating is computed over all reviews. However, some of them may be invisible to you due to the visibility setting chosen by the reviewers.

(0.0 of 5.0 based on 0 reviews)

Vaccination and antigenic drift in influenza

by: Maciej F. Boni

In: Vaccine, Vol. 26, Nr. Supplement 3 (2008) , p. C8 - C14.

Resources (URL, PDF, PS...)

URL:	http://www.sciencedirect.com/science/article/B6TD4-4SWWMM2-4/2/f2a706740c159981194c46d50c60b768
DOI:	10.1016/j.vaccine.2008.04.011

The relationship between influenza antigenic drift and vaccination lies at the intersection of evolutionary biology and public health, and it must be viewed and analyzed in both contexts simultaneously. In this paper, I review what is known about the effects of antigenic drift on vaccination and the effects of vaccination on antigenic drift, and I suggest some simple ways to detect the presence of antigenic drift in seasonal influenza data. If antigenic drift occurs on the time scale of a single influenza season, it may be associated with the presence of herd immunity at the beginning of the season and may indicate a need to monitor for vaccine updates at the end of the season. The relationship between antigenic drift and vaccination must also be viewed in the context of the global circulation of influenza strains and the seeding of local and regional epidemics. In the data sets I consider - from New Zealand, New York, and France - antigenic drift can be statistically detected during some seasons, and seeding of epidemics appears to be endogenous sometimes and exogenous at other times. Improved detection of short-term antigenic drift and epidemic seeding would significantly benefit influenza monitoring efforts and vaccine selection.

Description

ScienceDirect - Vaccine : Vaccination and antigenic drift in influenza

BibTeX record

@article{Boni2008C8,
  abstract = {The relationship between influenza antigenic drift and vaccination lies at the intersection of evolutionary biology and public health, and it must be viewed and analyzed in both contexts simultaneously. In this paper, I review what is known about the effects of antigenic drift on vaccination and the effects of vaccination on antigenic drift, and I suggest some simple ways to detect the presence of antigenic drift in seasonal influenza data. If antigenic drift occurs on the time scale of a single influenza season, it may be associated with the presence of herd immunity at the beginning of the season and may indicate a need to monitor for vaccine updates at the end of the season. The relationship between antigenic drift and vaccination must also be viewed in the context of the global circulation of influenza strains and the seeding of local and regional epidemics. In the data sets I consider - from New Zealand, New York, and France - antigenic drift can be statistically detected during some seasons, and seeding of epidemics appears to be endogenous sometimes and exogenous at other times. Improved detection of short-term antigenic drift and epidemic seeding would significantly benefit influenza monitoring efforts and vaccine selection.},
  added-at = {2009-07-04T05:46:38.000+0200},
  author = {Boni, Maciej F.},
  biburl = {http://www.bibsonomy.org/bibtex/2fdf9e11b615983b8ff2654cf824614de/ebo},
  description = {ScienceDirect - Vaccine : Vaccination and antigenic drift in influenza},
  doi = {DOI: 10.1016/j.vaccine.2008.04.011},
  interhash = {06e20231ef3da813ff4bd881a09cfbe6},
  intrahash = {fdf9e11b615983b8ff2654cf824614de},
  issn = {0264-410X},
  journal = {Vaccine},
  keywords = {epi evolution immunity},
  note = {The Evolutionary Consequences of Vaccination},
  number = {Supplement 3},
  pages = {C8 - C14},
  timestamp = {2009-07-04T05:46:38.000+0200},
  title = {Vaccination and antigenic drift in influenza},
  url = {http://www.sciencedirect.com/science/article/B6TD4-4SWWMM2-4/2/f2a706740c159981194c46d50c60b768},
  volume = 26,
  year = 2008
}

Endnote record

%0 Journal Article
%1 Boni2008C8
%A Boni, Maciej F.
%D 2008
%J Vaccine
%K 
%N Supplement 3
%P C8 - C14
%T Vaccination and antigenic drift in influenza
%R DOI: 10.1016/j.vaccine.2008.04.011
%U http://www.sciencedirect.com/science/article/B6TD4-4SWWMM2-4/2/f2a706740c159981194c46d50c60b768
%V 26
%X The relationship between influenza antigenic drift and vaccination lies at the intersection of evolutionary biology and public health, and it must be viewed and analyzed in both contexts simultaneously. In this paper, I review what is known about the effects of antigenic drift on vaccination and the effects of vaccination on antigenic drift, and I suggest some simple ways to detect the presence of antigenic drift in seasonal influenza data. If antigenic drift occurs on the time scale of a single influenza season, it may be associated with the presence of herd immunity at the beginning of the season and may indicate a need to monitor for vaccine updates at the end of the season. The relationship between antigenic drift and vaccination must also be viewed in the context of the global circulation of influenza strains and the seeding of local and regional epidemics. In the data sets I consider - from New Zealand, New York, and France - antigenic drift can be statistically detected during some seasons, and seeding of epidemics appears to be endogenous sometimes and exogenous at other times. Improved detection of short-term antigenic drift and epidemic seeding would significantly benefit influenza monitoring efforts and vaccine selection.