%0 Journal Article %1 karlin1977frequency %A Karlin, Samuel %D 1977 %J Theoretical Population Biology %K fishers_diffusion island_model patchy_landscapes selection spatial_structure %N 3 %P 356 - 385 %R 10.1016/0040-5809(77)90018-1 %T Gene frequency patterns in the Levene subdivided population model %U http://www.sciencedirect.com/science/article/pii/0040580977900181 %V 11 %X In the context of a multideme population structure subject to selection, migration, and mating forces, it is desired to ascertain the stable evolutionary outcomes for various classes of selection regimes. These include selection patterns as (i) a mosaic of local directed selection effects, (ii) overdominance throughout with varying intensities of the local heterozygote advantage, (iii) varying degrees of underdominance throughout, (iv) a mixed underdominant-overdominant regime. An accounting of the nature of the equilibrium configurations in the Levene population subdivision model was done with respect to the above classes of selection regimes. In particular, it is established that multiple polymorphic equilibria do not arise for selection structures (i) and (ii), while for the mixed underdominant-overdominant selection form (iv) with appropriate parameter ranges there can exist two stable internal equilibria. A surprising finding is that the number and/or character of the equilibria is not changed by increased population division beyond that of two habitats, while there is a significant difference in the equilibrium possibilities for a one- as against a two-deme population. These results appear to be a special limiting feature of the Levene population subdivision formulation. Levene's model is: large common mating pool, redistributed to "islands" in varying proportions.

@article{karlin1977frequency, abstract = {In the context of a multideme population structure subject to selection, migration, and mating forces, it is desired to ascertain the stable evolutionary outcomes for various classes of selection regimes. These include selection patterns as (i) a mosaic of local directed selection effects, (ii) overdominance throughout with varying intensities of the local heterozygote advantage, (iii) varying degrees of underdominance throughout, (iv) a mixed underdominant-overdominant regime. An accounting of the nature of the equilibrium configurations in the Levene population subdivision model was done with respect to the above classes of selection regimes. In particular, it is established that multiple polymorphic equilibria do not arise for selection structures (i) and (ii), while for the mixed underdominant-overdominant selection form (iv) with appropriate parameter ranges there can exist two stable internal equilibria. A surprising finding is that the number and/or character of the equilibria is not changed by increased population division beyond that of two habitats, while there is a significant difference in the equilibrium possibilities for a one- as against a two-deme population. These results appear to be a special limiting feature of the Levene population subdivision formulation. Levene's model is: large common mating pool, redistributed to "islands" in varying proportions.}, added-at = {2013-03-13T12:45:33.000+0100}, author = {Karlin, Samuel}, biburl = {https://www.bibsonomy.org/bibtex/2dcd2637af6e602f0df8eb627a655855d/peter.ralph}, doi = {10.1016/0040-5809(77)90018-1}, interhash = {3ee25ff5d00865b733394cad6dd25fae}, intrahash = {dcd2637af6e602f0df8eb627a655855d}, issn = {0040-5809}, journal = {Theoretical Population Biology}, keywords = {fishers_diffusion island_model patchy_landscapes selection spatial_structure}, number = 3, pages = {356 - 385}, timestamp = {2013-03-13T12:45:33.000+0100}, title = {Gene frequency patterns in the {Levene} subdivided population model}, url = {http://www.sciencedirect.com/science/article/pii/0040580977900181}, volume = 11, year = 1977 }