%0 Journal Article %1 Park2002 %A Park, Eun Sook %A Park, Chang Il %A Kim, Deog Young %A Kim, Yong Rae %D 2002 %J Arch Phys Med Rehabil %K Adolescent; Adult; Age Factors; Botulinum Toxin Type A; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Electric Stimulation; Evoked Potentials, Somatosensory; Female; Hemiplegia; Humans; Infant; Injections, Intramuscular; Magnetic Resonance Imaging; Male; Muscle Spasticity; Neuromuscular Agents; Reaction Time; Severity of Illness Index; Treatment Outcome %N 11 %P 1592--1596 %T The effect of spasticity on cortical somatosensory-evoked potentials: changes of cortical somatosensory-evoked potentials after botulinum toxin type A injection. %V 83 %X OBJECTIVE: To evaluate the changes in cortical somatosensory-evoked potentials (SEPs) after botulinum toxin type A injection to determine what effect spasticity has on cortical SEPs. DESIGN: Intervention study and before-after trial. SETTING: University-affiliated hospital in Korea. PARTICIPANTS: Twelve children with spastic hemiplegic cerebral palsy (CP), 7 children with spastic diplegic CP, and 8 patients with traumatic brain injury. INTERVENTION: All participants had botulinum toxin type A injected into the muscles of the spastic limb. MAIN OUTCOME MEASURES: SEPs were recorded before and 7 days after the botulinum toxin type A injection. Spasticity of the affected spastic limb was also measured. The short latency and amplitude of waves in SEPs were measured. The SEP results were divided into 3 groups: flat (no evoked potential), abnormal (evoked but delayed in latency), and normal (clear waveform with normal latency). RESULTS: The normal response of cortical SEP increased after injection. The SEPs exhibited more frequent improvement in the limbs, with greater improvement of spasticity in grade (>1.0 grade) and in patients of younger age (<3y) after injection (P<.05). CONCLUSION: The observed improvement of cortical SEPs with associated reduction of spasticity that occurred after the botulinum toxin type A injection indicates that spasticity itself can be considered a factor affecting cortical SEPs.

@article{Park2002, abstract = {OBJECTIVE: To evaluate the changes in cortical somatosensory-evoked potentials (SEPs) after botulinum toxin type A injection to determine what effect spasticity has on cortical SEPs. DESIGN: Intervention study and before-after trial. SETTING: University-affiliated hospital in Korea. PARTICIPANTS: Twelve children with spastic hemiplegic cerebral palsy (CP), 7 children with spastic diplegic CP, and 8 patients with traumatic brain injury. INTERVENTION: All participants had botulinum toxin type A injected into the muscles of the spastic limb. MAIN OUTCOME MEASURES: SEPs were recorded before and 7 days after the botulinum toxin type A injection. Spasticity of the affected spastic limb was also measured. The short latency and amplitude of waves in SEPs were measured. The SEP results were divided into 3 groups: flat (no evoked potential), abnormal (evoked but delayed in latency), and normal (clear waveform with normal latency). RESULTS: The normal response of cortical SEP increased after injection. The SEPs exhibited more frequent improvement in the limbs, with greater improvement of spasticity in grade (>1.0 grade) and in patients of younger age (<3y) after injection (P<.05). CONCLUSION: The observed improvement of cortical SEPs with associated reduction of spasticity that occurred after the botulinum toxin type A injection indicates that spasticity itself can be considered a factor affecting cortical SEPs.}, added-at = {2014-07-19T20:59:15.000+0200}, author = {Park, Eun Sook and Park, Chang Il and Kim, Deog Young and Kim, Yong Rae}, biburl = {https://www.bibsonomy.org/bibtex/2eec339ff4bd043a629fb97b08d7929cf/ar0berts}, groups = {public}, interhash = {42a739a039c96357c28fe6c2684a51f1}, intrahash = {eec339ff4bd043a629fb97b08d7929cf}, journal = {Arch Phys Med Rehabil}, keywords = {Adolescent; Adult; Age Factors; Botulinum Toxin Type A; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Electric Stimulation; Evoked Potentials, Somatosensory; Female; Hemiplegia; Humans; Infant; Injections, Intramuscular; Magnetic Resonance Imaging; Male; Muscle Spasticity; Neuromuscular Agents; Reaction Time; Severity of Illness Index; Treatment Outcome}, month = Nov, number = 11, pages = {1592--1596}, pii = {S0003999302002575}, pmid = {12422331}, timestamp = {2014-07-19T20:59:15.000+0200}, title = {The effect of spasticity on cortical somatosensory-evoked potentials: changes of cortical somatosensory-evoked potentials after botulinum toxin type A injection.}, username = {ar0berts}, volume = 83, year = 2002 }