%0 Journal Article %1 park_high-resolution_2006 %A Park, Sang Ho %A Prytulla, Stefan %A De Angelis, Anna A %A Brown, Jonathan Miles %A Kiefer, Hans %A Opella, Stanley J %D 2006 %J J. Am. Chem. Soc. %K Binding Proteins,Interleukin-8A,Lipid Resonance Sites,G-Protein-Coupled,GTP-Binding Spectroscopy,Protein Structure,Receptors,Secondary,Tertiary bilayers,Magnetic %N 23 %P 7402--7403 %R 10.1021/ja0606632 %T High-resolution \NMR\ spectroscopy of a \GPCR\ in aligned bicelles %V 128 %X Solid-state NMR spectra with single-site resolution of CXCR1, a G protein-coupled receptor (GPCR), were obtained in magnetically aligned phospholipid bicelles. These results demonstrate that GPCRs in phospholipid bilayers are suitable samples for structure determination by solid-state NMR. The spectra also enable studies of drug-receptor interactions.

@article{park_high-resolution_2006, abstract = {Solid-state NMR spectra with single-site resolution of CXCR1, a G protein-coupled receptor (GPCR), were obtained in magnetically aligned phospholipid bicelles. These results demonstrate that GPCRs in phospholipid bilayers are suitable samples for structure determination by solid-state NMR. The spectra also enable studies of drug-receptor interactions.}, added-at = {2017-03-14T02:48:56.000+0100}, author = {Park, Sang Ho and Prytulla, Stefan and {De Angelis}, Anna A and Brown, Jonathan Miles and Kiefer, Hans and Opella, Stanley J}, biburl = {https://www.bibsonomy.org/bibtex/2bd093c3c6ef0f3ca08d86829614b48d1/nmrresource}, doi = {10.1021/ja0606632}, interhash = {5b0fc40fc1d39f41133f28faabdd5865}, intrahash = {bd093c3c6ef0f3ca08d86829614b48d1}, issn = {0002-7863}, journal = {J. Am. Chem. Soc.}, keywords = {Binding Proteins,Interleukin-8A,Lipid Resonance Sites,G-Protein-Coupled,GTP-Binding Spectroscopy,Protein Structure,Receptors,Secondary,Tertiary bilayers,Magnetic}, month = jun, number = 23, pages = {7402--7403}, pmid = {16756269}, timestamp = {2017-03-14T02:49:21.000+0100}, title = {{High-resolution {\{}NMR{\}} spectroscopy of a {\{}GPCR{\}} in aligned bicelles}}, volume = 128, year = 2006 }