%0 Journal Article %1 Iqbal2015 %A Iqbal, Zahid %A Denon*, Yves Eric %A Sissinto, Yolande %A Tokponnon, Filémon %A Oke, Mariam %A Gazard, Dorothée Kinde %A Kossou, Hortense %A Gbenou, Dina %A Massougbodji, Achille %A Loko, Frederick %D 2014 %J International Journal of Microbiology and Mycology | IJMM %K Artemether-lumefantrine Artesunate-amodiaquine apyrexy clairance efficacy parasitologic therapeutic %N No. 2 %P p. 1-9 %T Comparative study of the effectiveness of combination therapies based on atemisinine in Dassa Zounme and Parakou: case of Artemether lumefantrine and Artesunate amodiaquine %U http://dx.doi.org/10.6084/m9.figshare.1379817 %V Vol. 2 %X The National Malaria Control Program recommended in 1993, the use of Chloroquina (CQ) as first line drug for malaria treatment, and sulfadoxin pyrimethamin as second drug. After years, Benin knows resistance about these antimalarials. Quinina was to treat gravities. In 2004, the strategy of treatment changed. Treatment of malaria cases is based on use of arteminisinia therapeutic combination. The goal of this study is to be sure that these drugs are efficace before general use in the country and in some regions as Dassa Zounmè where the resistance is up (61. 3% for Chloroquina CQ and 45.9% for SP in 2002).The study is based on: comparison of therapeutic efficacy of artemether Lumefantrine and Artesunate Amodiaquine. Results show that all of the tested drugs have good therapeutic efficacy. Most important rate failure is in Dassa Zounmè (33, 86%) than Parakou (23, 44%). They are parasitologic failure and are probably due to the reinfestation of children. Two drugs have a good parasitological clearance and eliminate fever after 2 days of treatment.

@article{Iqbal2015, abstract = {The National Malaria Control Program recommended in 1993, the use of Chloroquina (CQ) as first line drug for malaria treatment, and sulfadoxin pyrimethamin as second drug. After years, Benin knows resistance about these antimalarials. Quinina was to treat gravities. In 2004, the strategy of treatment changed. Treatment of malaria cases is based on use of arteminisinia therapeutic combination. The goal of this study is to be sure that these drugs are efficace before general use in the country and in some regions as Dassa Zounmè where the resistance is up (61. 3% for Chloroquina CQ and 45.9% for SP in 2002).The study is based on: comparison of therapeutic efficacy of artemether Lumefantrine and Artesunate Amodiaquine. Results show that all of the tested drugs have good therapeutic efficacy. Most important rate failure is in Dassa Zounmè (33, 86%) than Parakou (23, 44%). They are parasitologic failure and are probably due to the reinfestation of children. Two drugs have a good parasitological clearance and eliminate fever after 2 days of treatment.}, added-at = {2015-04-15T09:59:12.000+0200}, author = {Iqbal, Zahid and Denon*, Yves Eric and Sissinto, Yolande and Tokponnon, Filémon and Oke, Mariam and Gazard, Dorothée Kinde and Kossou, Hortense and Gbenou, Dina and Massougbodji, Achille and Loko, Frederick}, biburl = {https://www.bibsonomy.org/bibtex/2c4de7ea3cb6d6f1975dfc5942eb62666/rajzahid}, interhash = {6cc1fd158d15427fb392b514ce9656b5}, intrahash = {c4de7ea3cb6d6f1975dfc5942eb62666}, journal = {International Journal of Microbiology and Mycology | IJMM}, keywords = {Artemether-lumefantrine Artesunate-amodiaquine apyrexy clairance efficacy parasitologic therapeutic}, month = {03}, number = {No. 2}, pages = {p. 1-9}, timestamp = {2015-04-15T09:59:12.000+0200}, title = {{Comparative study of the effectiveness of combination therapies based on atemisinine in Dassa Zounme and Parakou: case of Artemether lumefantrine and Artesunate amodiaquine}}, url = {http://dx.doi.org/10.6084/m9.figshare.1379817}, volume = {Vol. 2}, year = 2014 }