%0 Journal Article %1 citeulike:12285040 %A de Sanjose, Silvia %A Benavente, Yolanda %A Vajdic, Claire M. %A Engels, Eric A. %A Morton, Lindsay M. %A Bracci, Paige M. %A Spinelli, John J. %A Zheng, Tongzhang %A Zhang, Yawei %A Franceschi, Silvia %A Talamini, Renato %A Holly, Elizabeth A. %A Grulich, Andrew E. %A Cerhan, James R. %A Hartge, Patricia %A Cozen, Wendy %A Boffetta, Paolo %A Brennan, Paul %A Maynadié, Marc %A Cocco, Pierluigi %A Bosch, Ramon %A Foretova, Lenka %A Staines, Anthony %A Becker, Nikolaus %A Nieters, Alexandra %D 2008 %J Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association %K imported %N 4 %P 451--458 %R 10.1016/j.cgh.2008.02.011 %T Hepatitis C and non-Hodgkin lymphoma among 4784 cases and 6269 controls from the International Lymphoma Epidemiology Consortium. %U http://dx.doi.org/10.1016/j.cgh.2008.02.011 %V 6 %X Increasing evidence points towards a role of hepatitis C virus (HCV) infection in causing malignant lymphomas. We pooled case-control study data to provide robust estimates of the risk of non-Hodgkin's lymphoma (NHL) subtypes after HCV infection. The analysis included 7 member studies from the International Lymphoma Epidemiology Consortium (InterLymph) based in Europe, North America, and Australia. Adult cases of NHL (n = 4784) were diagnosed between 1988 and 2004 and controls (n = 6269) were matched by age, sex, and study center. All studies used third-generation enzyme-linked immunosorbent assays to test for antibodies against HCV in serum samples. Participants who were human immunodeficiency virus positive or were organ-transplant recipients were excluded. HCV infection was detected in 172 NHL cases (3.60\%) and in 169 (2.70\%) controls (odds ratio OR, 1.78; 95\% confidence interval CI, 1.40-2.25). In subtype-specific analyses, HCV prevalence was associated with marginal zone lymphoma (OR, 2.47; 95\% CI, 1.44-4.23), diffuse large B-cell lymphoma (OR, 2.24; 95\% CI, 1.68-2.99), and lymphoplasmacytic lymphoma (OR, 2.57; 95\% CI, 1.14-5.79). Notably, risk estimates were not increased for follicular lymphoma (OR, 1.02; 95\% CI, 0.65-1.60). These results confirm the association between HCV infection and NHL and specific B-NHL subtypes (diffuse large B-cell lymphoma, marginal zone lymphoma, and lymphoplasmacytic lymphoma).

@article{citeulike:12285040, abstract = {{ Increasing evidence points towards a role of hepatitis C virus (HCV) infection in causing malignant lymphomas. We pooled case-control study data to provide robust estimates of the risk of non-Hodgkin's lymphoma (NHL) subtypes after HCV infection. The analysis included 7 member studies from the International Lymphoma Epidemiology Consortium (InterLymph) based in Europe, North America, and Australia. Adult cases of NHL (n = 4784) were diagnosed between 1988 and 2004 and controls (n = 6269) were matched by age, sex, and study center. All studies used third-generation enzyme-linked immunosorbent assays to test for antibodies against HCV in serum samples. Participants who were human immunodeficiency virus positive or were organ-transplant recipients were excluded. HCV infection was detected in 172 NHL cases (3.60\%) and in 169 (2.70\%) controls (odds ratio [OR], 1.78; 95\% confidence interval [CI], 1.40-2.25). In subtype-specific analyses, HCV prevalence was associated with marginal zone lymphoma (OR, 2.47; 95\% CI, 1.44-4.23), diffuse large B-cell lymphoma (OR, 2.24; 95\% CI, 1.68-2.99), and lymphoplasmacytic lymphoma (OR, 2.57; 95\% CI, 1.14-5.79). Notably, risk estimates were not increased for follicular lymphoma (OR, 1.02; 95\% CI, 0.65-1.60). These results confirm the association between HCV infection and NHL and specific B-NHL subtypes (diffuse large B-cell lymphoma, marginal zone lymphoma, and lymphoplasmacytic lymphoma). }}, added-at = {2013-04-20T15:12:48.000+0200}, author = {de Sanjose, Silvia and Benavente, Yolanda and Vajdic, Claire M. and Engels, Eric A. and Morton, Lindsay M. and Bracci, Paige M. and Spinelli, John J. and Zheng, Tongzhang and Zhang, Yawei and Franceschi, Silvia and Talamini, Renato and Holly, Elizabeth A. and Grulich, Andrew E. and Cerhan, James R. and Hartge, Patricia and Cozen, Wendy and Boffetta, Paolo and Brennan, Paul and Maynadi\'{e}, Marc and Cocco, Pierluigi and Bosch, Ramon and Foretova, Lenka and Staines, Anthony and Becker, Nikolaus and Nieters, Alexandra}, biburl = {https://www.bibsonomy.org/bibtex/2a7fc0b829a4c16d5d334abb28f1d6502/astaines}, citeulike-article-id = {12285040}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.cgh.2008.02.011}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18387498}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18387498}, doi = {10.1016/j.cgh.2008.02.011}, interhash = {acf601864e53160f9cbb8fbe7fe64a57}, intrahash = {a7fc0b829a4c16d5d334abb28f1d6502}, issn = {1542-7714}, journal = {Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association}, keywords = {imported}, month = apr, number = 4, pages = {451--458}, pmid = {18387498}, posted-at = {2013-04-20 12:55:41}, priority = {2}, timestamp = {2013-04-20T15:12:53.000+0200}, title = {{Hepatitis C and non-Hodgkin lymphoma among 4784 cases and 6269 controls from the International Lymphoma Epidemiology Consortium.}}, url = {http://dx.doi.org/10.1016/j.cgh.2008.02.011}, volume = 6, year = 2008 }