%0 Journal Article %1 Schmidt1981 %A Schmidt, W. %A Doerr, H. W. %A Roelcke, D. %A Kubli, F. %D 1981 %J Z Geburtshilfe Perinatol %K Adult; Cerebral Palsy; Female; Fetal Blood; Growth Retardation; Humans; Immunoglobulin A; M; Immunologic Deficiency Syndromes; Infant, Newborn; Male; Microcephaly; Pregnancy; Pregnancy Complications; Complications, Infectious %N 5 %P 268--272 %T Determinations of immunoglobulin from the blood of the umbilical vein after pathological course of pregnancy and in foetal growth retardation (author's transl) %V 185 %X Serum-IgM and serum-IgA concentrations of 561 unselected samples of umbilical cord were determined by the radial immunodiffusion method (Mancini's technique). The mean IgM value of all blood samples was 13.8 mg\%. In 9.9\% of all cases only we found measurable IgA values, the average IgA concentration being 4.5 mg\%. Elevated IgM values (greater than 30 mg\%) - pointing to an intrauterine infection - were found to be more frequent (12.1\%) in foetal of growth retardation than with newborn of normal body weight, where the incidence of increased IgM values was 5.5\% of the examined cases only (however, without a statistically significant difference). In preceding infections during pregnancy, elevated IgM values (greater than 30 mg\%) were also found more frequently than in cases without infections (11.8\% vs. 5.7\%, respectively). Basing on these results, we can suspect that intrauterine infection is one of the possible causes of foetal growth retardation, but not one of the main ones.

@article{Schmidt1981, abstract = {Serum-IgM and serum-IgA concentrations of 561 unselected samples of umbilical cord were determined by the radial immunodiffusion method (Mancini's technique). The mean IgM value of all blood samples was 13.8 mg\%. In 9.9\% of all cases only we found measurable IgA values, the average IgA concentration being 4.5 mg\%. Elevated IgM values (greater than 30 mg\%) - pointing to an intrauterine infection - were found to be more frequent (12.1\%) in foetal of growth retardation than with newborn of normal body weight, where the incidence of increased IgM values was 5.5\% of the examined cases only (however, without a statistically significant difference). In preceding infections during pregnancy, elevated IgM values (greater than 30 mg\%) were also found more frequently than in cases without infections (11.8\% vs. 5.7\%, respectively). Basing on these results, we can suspect that intrauterine infection is one of the possible causes of foetal growth retardation, but not one of the main ones.}, added-at = {2014-07-19T21:17:25.000+0200}, author = {Schmidt, W. and Doerr, H. W. and Roelcke, D. and Kubli, F.}, biburl = {https://www.bibsonomy.org/bibtex/2fc6540dc41590dbbd9783a0456da8e64/ar0berts}, groups = {public}, interhash = {fca2e01eb2fbff61a956ff6aca155bcb}, intrahash = {fc6540dc41590dbbd9783a0456da8e64}, journal = {Z Geburtshilfe Perinatol}, keywords = {Adult; Cerebral Palsy; Female; Fetal Blood; Growth Retardation; Humans; Immunoglobulin A; M; Immunologic Deficiency Syndromes; Infant, Newborn; Male; Microcephaly; Pregnancy; Pregnancy Complications; Complications, Infectious}, month = Oct, number = 5, pages = {268--272}, pmid = {7198337}, timestamp = {2014-07-19T21:17:25.000+0200}, title = {[Determinations of immunoglobulin from the blood of the umbilical vein after pathological course of pregnancy and in foetal growth retardation (author's transl)]}, username = {ar0berts}, volume = 185, year = 1981 }