]> BibSonomy publications for /author/Paul/%28Genetics%29%2C http://www.bibsonomy.org/burst/author/Paul/%28Genetics%29%2C BibSonomy BuRST Feed for /author/Paul/%28Genetics%29%2C 2008-07-20T23:48:37+02:00 De novo repeat classification and fragment assembly http://www.bibsonomy.org/bibtex/251d90db8174d7d1da830b654951e5ea0/dzerbino dzerbino 2007-09-17T20:19:41+02:00 (Genetics), Acid, Algorithms, Alignment, Analysis, Artificial, Bacterial, Biology, Chromosomes, Cluster Computational Contig Family Genome, Human, Humans, Linkage Mapping, Multigene Nucleic Repetitive Sequence Sequences,
De novo repeat classification and fragment assembly
Pavel A Pevzner and Paul A Pevzner and Haixu Tang and Glenn Tesler Genome Res 14 1786--96 (2004)
to (Genetics), Acid, Algorithms, Alignment, Analysis, Artificial, Bacterial, Biology, Chromosomes, Cluster Computational Contig Family Genome, Human, Humans, Linkage Mapping, Multigene Nucleic Repetitive Sequence Sequences, by dzerbino on 2007-09-17 20:19:41 ]]> Genome ResSep91786--96De novo repeat classification and fragment assembly142004(Genetics), Acid, Algorithms, Alignment, Analysis, Artificial, Bacterial, Biology, Chromosomes, Cluster Computational Contig Family Genome, Human, Humans, Linkage Mapping, Multigene Nucleic Repetitive Sequence Sequences, 2007-09-17 20:19:41.0Repetitive sequences make up a significant fraction of almost any genome, and an important and still open question in bioinformatics is how to represent all repeats in DNA sequences. We propose a new approach to repeat classification that represents all repeats in a genome as a mosaic of sub-repeats. Our key algorithmic idea also leads to new approaches to multiple alignment and fragment assembly. In particular, we show that our FragmentGluer assembler improves on Phrap and ARACHNE in assembly of BACs and bacterial genomes.