]> BibSonomy publications for /bibtex/1cb97ab154486a990aec066611a814420 http://www.bibsonomy.org/burst/bibtex/1cb97ab154486a990aec066611a814420 BibSonomy BuRST Feed for /bibtex/1cb97ab154486a990aec066611a814420 2008-08-21T04:19:15+02:00 TARGET: a new method for predicting protein subcellular localization in eukaryotes http://www.bibsonomy.org/bibtex/27f3e5b09760a129ba9b6cd73a6b92ecb/marcoalvarez marcoalvarez 2008-05-14T11:33:59+02:00 SubCellLoc
TARGET: a new method for predicting protein subcellular localization in eukaryotes
Chittibabu Guda and Shankar Subramaniam Bioinformatics 21 3963--3969 (2005)
to SubCellLoc by marcoalvarez on 2008-05-14 11:33:59 ]]> Bioinformatics213963--3969TARGET: a new method for predicting protein subcellular localization in eukaryotes212005SubCellLoc 2008-05-14 11:33:59.0Motivation: There is a scarcity of efficient computational methods for predicting protein subcellular localization in eukaryotes. Currently available methods are inadequate for genome-scale predictions with several limitations. Here, we present a new prediction method, pTARGET that can predict proteins targeted to nine different subcellular locations in the eukaryotic animal species. Results: The nine subcellular locations predicted by pTARGET include cytoplasm, endoplasmic reticulum, extracellular/secretory, golgi, lysosomes, mitochondria, nucleus, plasma membrane and peroxisomes. Predictions are based on the location-specific protein functional domains and the amino acid compositional differences across different subcellular locations. Overall, this method can predict 68--87% of the true positives at accuracy rates of 96--99%. Comparison of the prediction performance against PSORT showed that pTARGET prediction rates are higher by 11--60% in 6 of the 8 locations tested. Besides, the pTARGET method is robust enough for genome-scale prediction of protein subcellular localizations since, it does not rely on the presence of signal or target peptides. Availability: A public web server based on the pTARGET method is accessible at the URL http://bioinformatics.albany.edu/~ptarget. Datasets used for developing pTARGET can be downloaded from this web server. Source code will be available on request from the corresponding author. TARGET: a new method for predicting protein subcellular localization in eukaryotes. dblphttp://www.bibsonomy.org/bibtex/2de4ef89e9360b7478b4ecb80c9012768/dblp dblp 2006-07-28T00:00:00+02:00 dblp
TARGET: a new method for predicting protein subcellular localization in eukaryotes.
Chittibabu Guda and Shankar Subramaniam Bioinformatics 21 3963-3969 (2005)
to dblp by dblp on 2006-07-28 00:00:00 ]]> Bioinformatics213963-3969TARGET: a new method for predicting protein subcellular localization in eukaryotes.212005dblp 2006-07-28 00:00:00.0