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AuthorTitleYearJournal/ProceedingsReftypeDOI/URL
David, B., Zanelli, F. & Z'Graggen, F. Teaching CAD in an architectural school with the SIGMA-ARCHI system.

[BibTeX]

 1979 Computers & Graphics   article URL  
BibTeX: 
@article{journals/cg/DavidZZ79,
  author = {B. David and F. Zanelli and François-Joseph Z'Graggen},
  title = {Teaching CAD in an architectural school with the SIGMA-ARCHI system.},
  journal = {Computers & Graphics},
  year = {1979},
  volume = {4},
  number = {3-4},
  pages = {193-199},
  url = {http://dblp.uni-trier.de/db/journals/cg/cg4.html#DavidZZ79}
}
Fantappiè, S., Corsini, A., Sidoli, A., Uboldi, P., Granata, A., Zanelli, T., Rossi, P., Marcovina, S., Fumagalli, R. & Catapano, A. L. Monoclonal antibodies to human low density lipoprotein identify distinct areas on apolipoprotein B-100 relevant to the low density lipoprotein-receptor interaction.

[Abstract] [BibTeX]

 1992 Journal of Lipid Research   article URL  
Abstract: We have characterized the epitopes for ten murine monoclonal antibodies (Mabs) to human low density lipoprotein (LDL) and studied their ability to interfere with the LDL-receptor interaction. The epitopes for the antibodies were defined by using the following approaches: 1) interaction with apoB-48; 2) interaction with apoB-100 thrombolytic fragments; and 3) interaction with beta-galactosidase-apoB fusion proteins spanning different areas of the apoB-100 sequence. The results obtained are consistent with the following map of epitopes: Mab 6E, amino acids (aa) 1-1297, Mabs 5A and 6B, aa 1480-1693, Mabs 2A, 7A, 3B, and 4B, aa 2152-2377, Mabs 8A and 9A, aa 2657-3248 and 3H, aa 4082-4306. Four Mabs (2A, 5A, 7A, and 9A) whose epitopes are located in three different areas of apoB, dramatically reduced (up to 95%) the LDL-receptor interaction on cultured human fibroblasts; Fab fragments were as effective as the whole antibodies. Mab 3H, on the other hand, increased LDL binding up to threefold. These findings are consistent with the hypothesis that several areas of apoB-100 are involved independently or in concert in modulating the apoprotein B conformation required for interaction with the LDL receptor.
BibTeX: 
@article{citeulike:477494,
  author = {S. Fantappiè and A. Corsini and A. Sidoli and P. Uboldi and A. Granata and T. Zanelli and P. Rossi and S. Marcovina and R. Fumagalli and A. L. Catapano},
  title = {Monoclonal antibodies to human low density lipoprotein identify distinct areas on apolipoprotein B-100 relevant to the low density lipoprotein-receptor interaction.},
  journal = {Journal of Lipid Research},
  year = {1992},
  volume = {33},
  number = {8},
  pages = {1111--1121},
  url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve\&db=pubmed\&dopt=Abstract\&list_uids=1279088}
}

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