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Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors

, , , , , , and . Am.J.Pathol., 151 (6): 1523-1530 (1997)

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Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors, , , , , , and . Am.J.Pathol., 151 (6): 1523-1530 (1997)Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis, , , , , , , , , and 6 other author(s). Cancer Cell, 7 (1): 101-111 (2005)Tumor angiogenesis. N.Engl.J.Med., 358 (19): 2039-2049 (2008)A naturally occurring soluble form of vascular endothelial growth factor receptor 2 detected in mouse and human plasma, , , , , , , and . Mol.Cancer Res., 2 (6): 315-326 (2004)Increased plasma vascular endothelial growth factor (VEGF) as a surrogate marker for optimal therapeutic dosing of VEGF receptor-2 monoclonal antibodies, , , , , , , , , and 4 other author(s). Cancer Res., 64 (18): 6616-6625 (2004)Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth, , , , , , , , , and . Cancer Res., 68 (2): 521-529 (2008)Molecular and cellular biomarkers for angiogenesis in clinical oncology, , , and . Drug Discov.Today, 12 (19-20): 806-812 (2007)Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy, , , , and . Proc.Natl.Acad.Sci.U.S.A, 104 (43): 17069-17074 (2007)