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Use of etoposide in patients with organ dysfunction: pharmacokinetic and pharmacodynamic considerations
Clinton F. Stewart Cancer Chemotherapy and Pharmacology 34(0):S76-S83 (1994/01/01/)
to imported by hruehs on Feb 4, 2010, 4:31 PM
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Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: The npde add-on package for R
E. Comets, K. Brendel, and F. Mentre COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE 90(2):154-166 (2008)
to DESIGNS NONMEM P-VALUES POPULATION evaluation mixed-effects model nonlinear npde pharmacodynamics pharmacokinetics population by hruehs on Feb 4, 2010, 4:31 PM
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Population pharmacokinetic approach to compare oral and i.v. administration of etoposide
G. Würthwein, S. Krümpelmann, B. Tillmann, E. Real, P. Schulze-Westhoff, H. Jürgens, and J. Boos Anti-cancer drugs 10(9):807-814 (1999)
to & Administration, Adolescent Adult Aged Agents, Antineoplastic Area Availability Biological Child Child, Chromatography, Curve Dose-Response Drug Etoposideadministration Factors Female High Humans Infant Infusions, Intravenous Liquid Male Middle Oral Phytogenicadministration Preschool Pressure Relationship, Time Under dosagebloodpharmacokinetics by hruehs on Feb 4, 2010, 4:31 PM
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Estimation of creatinine clearance in end-stage liver disease
Nix, B. L. Erstad, P. Z. Nakazato, J. F. Barletta, K. R. Matthias, and T. S. Krueger ANNALS OF PHARMACOTHERAPY 40(5):900-908 (2006)
to CIRRHOSIS CREATININE GLOMERULAR-FILTRATION-RATE MARKERS PREDICTABILITY PREDICTION RENAL-FUNCTION SERUM SURVIVAL TRANSPLANTATION assay clearance creatinine disease function liver renal by hruehs on Feb 4, 2010, 4:31 PM
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Etoposide pharmacokinetics and survival in patients with small cell lung cancer: a multicentre study
Benoit You, Brigitte Tranchand, Pascal Girard, Claire Falandry, Benjamin Ribba, Sylvie Chabaud, Pierre-Jean Souquet, Isabelle Court-Fortune, Véronique Trillet-Lenoir, Cécile Fournel, Michel Tod, and Gilles Freyer Lung cancer Amsterdam, Netherlands 62(2):261-272 (2008)
to & 80 Adult Aged Aged, Antineoplastic Area Carboplatinadministration Carcinomadrug Cell Chemotherapy Chromatography, Clearance Combined Curve Doxorubicinadministration Estimate Etoposideadministration Female Hazards High Humans Ifosfamideadministration Kaplan-Meiers Liquid Lung Male Mesnaadministration Metabolic Middle Models Neoplasmsdrug Pressure Prognosis Proportional Protocolspharmacokineticstherapeutic Rate Small Under and dosage dosagepharmacokinetics over therapymortality use by hruehs on Feb 4, 2010, 4:31 PM
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Population Pharmacokinetic-Pharmacodynamic Model for Neutropenia with Patient Subgroup Identification: Comparison across Anticancer Drugs
Charlotte Kloft, Johan Wallin, Anja Henningsson, Etienne Chatelut, and Mats O. Karlsson Clin Cancer Res 12(18):5481-5490 (2006)
to imported by hruehs on Feb 4, 2010, 4:31 PM
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Comparison of stepwise covariate model building strategies in population pharmacokinetic-pharmacodynamic analysis
Ulrika Wählby, E. Niclas Jonsson, and Mats O. Karlsson AAPS pharmSci 4(4):E27 (2002)
to Bias Models, Pharmacokinetics Predictive Selection Statistical Tests Value of by hruehs on Feb 4, 2010, 4:31 PM
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The lasso--a novel method for predictive covariate model building in nonlinear mixed effects models
Jakob Ribbing, Joakim Nyberg, Ola Caster, and E. Niclas Jonsson Journal of Pharmacokinetics and Pharmacodynamics 34(4):485-517 (2007)
to Agentspharmacokinetics Algorithms Analysis Chlormethiazolepharmacokinetics Computer Dynamics Humans Linear Models Models, Neuroprotective Nonlinear Pharmacokinetics Regression Simulation Statistical Strokedrug therapy by hruehs on Feb 4, 2010, 4:31 PM
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Assumption Testing in Population Pharmacokinetic Models: Illustrated with an Analysis of Moxonidine Data from Congestive Heart Failure Patients
Mats O. Karlsson, E. Niclas Jonsson, Curtis G. Wiltse, and Janet R. Wade Journal of Pharmacokinetics and Pharmacodynamics 26(2):207-246 (1998)
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Population pharmacokinetics of high-dose etoposide in children receiving different conditioning regimens
Gudrun Würthwein, Thomas Klingebiel, Sebastian Krümpelmann, Melanie Metz, Kerstin Schwenker, Karen Kranz, Claudia Lanvers, and Joachim Boos Anti-Cancer Drugs 13(1):101-110 (2002)
to imported by hruehs on Feb 4, 2010, 4:31 PM
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Pharmakokinetik
Hartmut Derendorf, Thomas Gramatté, and Hans Günther Schäfer Wiss. Verl.-Ges., Stuttgart, 2., vollst. überarb. und erw. Aufl. edition, (2002)
to imported by hruehs on Feb 4, 2010, 4:31 PM
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Models for time-varying covariates in population pharmacokinetic-pharmacodynamic analysis
Ulrika Wählby, Alison H. Thomson, Peter A. Milligan, and Mats O. Karlsson British Journal of Clinical Pharmacology 58(4):367-377 (2004)
to Analysis Chemical Factors Gentamicinspharmacokineticspharmacology Humans Models, Pefloxacinpharmacokineticspharmacology Pharmacokinetics Pharmacology Pyrimidinespharmacokineticspharmacology Regression Time Triazolespharmacokineticspharmacology by hruehs on Feb 4, 2010, 4:31 PM
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Pharmacokinetics and Pharmacodynamics of Oral Etoposide in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia
Mathew J. Edick, Amar Gajjar, Hazem H. Mahmoud, Matthijs E. C. van de Poll, Patricia L. Harrison, John C. Panetta, Gaston K. Rivera, Raul C. Ribeiro, John T. Sandlund, James M. Boyett, Ching-Hon Pui, and Mary V. Relling J Clin Oncol 21(7):1340-1346 (2003)
to imported by hruehs on Feb 4, 2010, 4:31 PM
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Pharmacokinetics of Etoposide in Patients with Abnormal Renal and Hepatic Function
Maurizio D'Incalci, Cosmo Rossi, Massimo Zucchetti, Renato Urso, Franco Cavalli, Costantino Mangioni, Yvonne Willems, and Cristiana Sessa Cancer Res 46(5):2566-2571 (1986)
to imported by hruehs on Feb 4, 2010, 4:31 PM
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Synopsis der Biopharmazie und Pharmakokinetik
Heinrich P. Koch, and Wolfgang A. Ritschel Ecomed, Landsberg, (1986)
to imported by hruehs on Feb 4, 2010, 4:31 PM
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Some suggestions for measuring predictive performance
L. B. Sheiner, and S. L. Beal Journal of pharmacokinetics and biopharmaceutics 9(4):503-512 (1981)
to Biological Kinetics Models, Pharmaceutical Preparationsmetabolism by hruehs on Feb 4, 2010, 4:31 PM
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Mechanism-based concepts of size and maturity in pharmacokinetics
B. J. Anderson, and N. H. G. Holford Annual review of pharmacology and toxicology (2008)
to & Adolescent Adult Age Biological Body Child Child, Compositionphysiology Dose-Response Drug Factors Humans Infant Infant, Models, Newborn Pharmaceutical Pharmacokinetics Preparationsadministration Preschool Relationship, Sizephysiology Weightphysiology dosage by hruehs on Feb 4, 2010, 4:31 PM
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A comparison of prediction equations for estimating glomerular filtration rate in adults without kidney disease
J. Lin, E. L. Knight, M. L. Hogan, and A. K. Singh JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 14(10):2573-2580 (2003)
to CHRONIC CLEARANCE CREATININE INULIN RENAL-INSUFFICIENCY SERUM by hruehs on Feb 4, 2010, 4:31 PM
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Ansätze zur Optimierung der Chemotherapie mit Etoposid auf der Grundlage pharmakokinetischer Untersuchungen
Stefanie Reif Shaker, Aachen, (2002)
to Etoposid Pharmakokinetik by hruehs on Feb 4, 2010, 4:31 PM
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Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide
K. Brendel, E. Comets, C. Laffont, C. Laveille, and F. Mentre PHARMACEUTICAL RESEARCH 23(9):2036-2049 (2006)
to DEVELOPMENT DRUG MODIFIED PERFORMANCE PREDICTIVE RELEASE Simulation VALIDATION check evaluation external metrics model pharmacokinetics population posterior predictive validation by hruehs on Feb 4, 2010, 4:31 PM
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