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Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage

N. Henke, R. Schmidt-Ullrich, R. Dechend, J. K. Park, F. Qadri, M. Wellner, M. Obst, V. Gross, R. Dietz, F. C. Luft, C. Scheidereit, and D. N. Muller. Circ.Res. 101(3):268-276 (2007)

3 years and 4 months ago

by kanefendt

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& Adhesion Albuminuria Angiotensin Animals Atherosclerosis B Blood C57BL Cardiovascular Cell Cells Chain Chloride Cultured Dietary Diseases Endothelial Ester Expression Factor-alpha Fusion Gene Humans Hypertension I-kappa II III Inbred Inflammation Intercellular Kidney Methyl Mice Models Molecule-1 NF-kappa NG-Nitroarginine Necrosis Nephritis Nitric Organ Oxide Polymerase Pressure Proteins Reaction Receptor Recombinant Regulation Research Reverse Signal Sodium Specificity Synthase TIE-1 Transcriptase Transduction Transgenic Tumor Type Vascular antagonists biosynthesis blood cells complications control etiology genetics inhibitors metabolism physiology physiopathology prevention protein toxicity

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The biology of epidermal growth factor receptor and its value as a prognostic/predictive factor

A. P. Dei Tos. Int.J.Biol.Markers 22(1 Suppl 4):S3-S9 (2007)

3 years and 4 months ago

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Surrogate predictive biomarkers for response to anti-EGFR agents: state of the art and challenges

F. Cappuzzo, L. Toschi, G. Finocchiaro, C. Ligorio, and A. Santoro. Int.J.Biol.Markers 22(1 Suppl 4):S10-S23 (2007)

3 years and 4 months ago

by kanefendt

2

& Antibodies Biological Carcinoma Dosage Drug Epidermal Factor Gene Growth Human Humans Immunohistochemistry Inhibitors Kinase Kinases Lung Markers Monoclonal Mutation Neoplasm Neoplasms Non-Small-Cell Phosphoproteins Predictive Protein Protein-Tyrosine Proteins Proto-Oncogene Quinazolines Receptor Resistance Tests Tyrosine Value analysis antagonists c-akt drug effects erbB-2 erbB-3 genetics identify inhibitors of protein response therapeutic therapy use

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The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on

P. Chomczynski, and N. Sacchi. Nat.Protoc. 1(2):581-585 (2006)

3 years and 4 months ago

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Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome

M. J. Cuadrado, P. Buendia, F. Velasco, M. A. Aguirre, N. Barbarroja, L. A. Torres, M. Khamashta, and C. Lopez-Pedrera. J.Thromb.Haemost. 4(11):2461-2469 (2006)

3 years and 4 months ago

by kanefendt

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& A Adolescent Adult Aged Antibodies Antiphospholipid Cells Cultured Endothelial Enzyme Expression Factor Female Gene Growth Human Humans Imidazoles Inhibitors Kinase Kinases MAP Male Middle Mitogen-Activated Monocytes Phenotype Protein Pyridines Receptor-1 Regulation Research Signaling Syndrome System Thromboplastin Thrombosis Tyrosine Vascular antagonists biosynthesis cells drug effects inhibitors metabolism p38 pathology pharmacology protein

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Vascular endothelial growth factor protein levels and gene expression in peripheral monocytes after stenting: a randomized comparative study of sirolimus-eluting and bare-metal stents

F. S. Czepluch, and J. Waltenberger. Eur.Heart J. 29(15):1924-1925 (2008)

3 years and 4 months ago

by kanefendt

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Expression Gene Monocytes protein

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Angiogenesis induced by hVEGF165 gene controlled by hypoxic response elements in rabbit ischemia myocardium

H. Dong, Q. Wang, Y. Zhang, B. Jiang, X. Xu, and Z. Zhang. Exp.Biol.Med.Maywood. 234(12):1417-1424 (2009)

3 years and 4 months ago

by kanefendt

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Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

T. Tammela, G. Zarkada, E. Wallgard, A. Murtomaki, S. Suchting, M. Wirzenius, M. Waltari, M. Hellstrom, T. Schomber, R. Peltonen, C. Freitas, A. Duarte, H. Isoniemi, P. Laakkonen, G. Christofori, S. Yla-Herttuala, M. Shibuya, B. Pytowski, A. Eichmann, C. Betsholtz, and K. Alitalo. Nature 454(7204):656-660 (2008)

3 years and 4 months ago

by kanefendt

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& Adult Angiogenesis Animals Antibodies BALB Blood C Cell Cells Dipeptides Down-Regulation Endothelial Endothelium Expression Factor Factors Female Gene Growth Humans Inbred Inhibitors Laboratories Ligands Line Lymphangiogenesis Mice Monoclonal Neoplasms Neoplastic Neovascularization Notch Pathologic Proliferation Receptor-3 Receptors Regulation Research Signal Transduction Transgenic Tumor Tyrosine Vascular Vessels antagonists blood cells drug effects genetics inhibitors metabolism pharmacology supply therapy

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Hypoxia-induced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines

N. Simiantonaki, C. Jayasinghe, R. Michel-Schmidt, K. Peters, M. I. Hermanns, and C. J. Kirkpatrick. Int.J.Oncol. 32(3):585-592 (2008)

3 years and 4 months ago

by kanefendt

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Molecular biology and pathology of lymphangiogenesis

T. Karpanen, and K. Alitalo. Annu.Rev.Pathol. (2008)

3 years and 4 months ago

by kanefendt

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Vascular endothelial growth factor protein levels and gene expression in peripheral monocytes after stenting: a randomized comparative study of sirolimus: eluting and bare metal stents

G. E. Kochiadakis, M. E. Marketou, D. Panutsopulos, D. A. Arfanakis, E. I. Skalidis, N. E. Igoumenidis, M. I. Hamilos, G. Sourvinos, G. Chlouverakis, D. Spandidos, and P. E. Vardas. Eur.Heart J. 29(6):733-740 (2008)

3 years and 4 months ago

by kanefendt

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Down-Regulation Expression Gene Monocytes Research Sirolimus Up-Regulation methods protein

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Expression of vascular endothelial growth factor-C and its receptor in osteosarcomas

H. R. Park, K. Min, H. S. Kim, W. W. Jung, and Y. K. Park. Pathol.Res.Pract. 204(8):575-582 (2008)

3 years and 4 months ago

by kanefendt

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Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: a fluorescent in situ hybridization study

N. Personeni, S. Fieuws, H. Piessevaux, Hertogh G. De, Schutter J. De, B. Biesmans, Roock W. De, A. Capoen, M. biec Rychter, J. L. van Laethem, M. Peeters, Y. Humblet, Cutsem E. Van, and S. Tejpar. Clin.Cancer Res. 14(18):5869-5876 (2008)

3 years and 4 months ago

by kanefendt

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Glucocorticoids suppress tumor lymphangiogenesis of prostate cancer cells

A. Yano, Y. Fujii, A. Iwai, S. Kawakami, Y. Kageyama, and K. Kihara. Clin.Cancer Res. 12(20 Pt 1):6012-6017 (2006)

3 years and 4 months ago

by kanefendt

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Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathway

B. Q. Shen, D. Y. Lee, and T. F. Zioncheck. J.Biol.Chem. 274(46):33057-33063 (1999)

3 years and 4 months ago

by kanefendt

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& A Adrenal Animals Aorta C Cattle Cell Cells Cortex Cultured Endothelial Endothelium Enzyme Enzymologic Ester Expression Factor Factors Gene Growth II Inhibitors Kinase Kinases Line Lymphokines Methyl NG-Nitroarginine Nitric Oxide Penicillamine Pharmacokinetics Protein Protein-Tyrosine Proteins Receptor Receptors Recombinant Regulation Signal Substances Synthase Transduction Type Tyrosine Up-Regulation Vascular analogs cells derivatives drug effects metabolism pharmacology protein

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Cardiovascular failure in mouse embryos deficient in VEGF receptor-3

D. J. Dumont, L. Jussila, J. Taipale, A. Lymboussaki, T. Mustonen, K. Pajusola, M. Breitman, and K. Alitalo. Science 282(5390):946-949 (1998)

3 years and 4 months ago

by kanefendt

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Adult Animals Antigens Blood C CD31 Cardiovascular Cell Chemistry Development Embryo Embryonic Endothelial Endothelium Factor Factors Fetal Gene Growth Hematopoiesis Heterozygote Homozygote Hybridization Immunohistochemistry In Kinase Kinases Ligands Lymphatic Mammalian Mice Neovascularization Physiologic Protein-Tyrosine Receptor Receptor-3 Receptors Research Signal Situ Surface System Targeting Transduction Vascular Vessels analysis and blood embryology genetics physiology supply

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Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets

R. Mohle, D. Green, M. A. Moore, R. L. Nachman, and S. Rafii. Proc.Natl.Acad.Sci.U.S.A 94(2):663-668 (1997)

3 years and 4 months ago

by kanefendt

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A Alternative Blood Cell Cells Complex Cultured Cytokines Endothelial Endothelium Expression Factor Factors GPIIb-IIIa Gene Glycoprotein Growth Hematopoiesis Human Humans Immunohistochemistry Kinase Kinases Laboratories Line Lymphokines Megakaryocytes Neovascularization Physiologic Platelet Platelets Protein-Tyrosine Receptor Receptors Research Splicing Thrombin Vascular analysis cells cytology genetics metabolism pharmacology protein secretion

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VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells

J. D. Hood, C. J. Meininger, M. Ziche, and H. J. Granger. Am.J.Physiol 274(3 Pt 2):H1054-H1058 (1998)

3 years and 4 months ago

by kanefendt

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Differential binding characteristics and cellular inhibition by soluble VEGF receptors 1 and 2

W. Roeckl, D. Hecht, H. Sztajer, J. Waltenberger, A. Yayon, and H. A. Weich. Exp.Cell Res. 241(1):161-170 (1998)

3 years and 4 months ago

by kanefendt

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& A Agents Animals BALB Binding C Cell Cells Cloning Competitive Cross-Linking Dimerization Endothelial Expression Factor Factors Fibrinolytic Gene Growth Heparin Human Humans Inbred Kinase Kinases Ligands Lymphokines Mice Mitogens Molecular Plastics Proliferation Protein Protein-Tyrosine Proteins Proto-Oncogene Reagents Receptor Receptor-1 Receptors Research Solubility Tyrosine Vascular antagonists cells drug effects genetics inhibitors isolation metabolism pharmacology protein purification

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Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors

A. M. Petit, J. Rak, M. C. Hung, P. Rockwell, N. Goldstein, B. Fendly, and R. S. Kerbel. Am.J.Pathol. 151(6):1523-1530 (1997)

3 years and 4 months ago

by kanefendt

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A Adenocarcinoma Animals Antibodies Breast Carcinoma Cell Cells Cultured Dose-Response Down-Regulation Drug Endothelial Epidermal Expression Factor Factors Gene Growth Human Humans Immunoenzyme Lymphokines Mice Monoclonal Neoplasm Neoplasms Neoplastic Neovascularization Neutralization Nude Oncogenes Pathologic Proliferation Receptor Regulation Relationship Research Signal Squamous Survival Techniques Tests Transduction Transplantation Tumor Tyrosine Vascular blood cells drug effects erbB-2 immunology metabolism pathology pharmacology physiology protein therapy

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