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Harmonization of strategies for the validation of quantitative analytical procedures. A SFSTP proposal--part II
P. Hubert, J. J. Nguyen-Huu, B. Boulanger, E. Chapuzet, P. Chiap, N. Cohen, P. A. Compagnon, W. Dewe, M. Feinberg, M. Lallier, M. Laurentie, N. Mercier, G. Muzard, C. Nivet, L. Valat, and E. Rozet J.Pharm.Biomed.Anal. 45(1):70-81 (2007)
to Analytical Calibration Chemistry Clinical France Laboratories Laboratory Medical Pharmaceutical Reference Reproducibility Research Results Societies Standards Techniques methods of standards by kanefendt on Feb 5, 2010, 11:28 AM
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Harmonization of strategies for the validation of quantitative analytical procedures. A SFSTP proposal--part III
P. Hubert, J. J. Nguyen-Huu, B. Boulanger, E. Chapuzet, N. Cohen, P. A. Compagnon, W. Dewe, M. Feinberg, M. Laurentie, N. Mercier, G. Muzard, L. Valat, and E. Rozet J.Pharm.Biomed.Anal. 45(1):82-96 (2007)
to & Analytical Calibration Chemistry Clinical France Laboratories Laboratory Medical Pharmaceutical Reference Reproducibility Research Results Societies Standards Techniques data methods numerical of standards statistics by kanefendt on Feb 5, 2010, 11:28 AM
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Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization
D. Fukumura, and R. K. Jain Microvasc.Res. 74(2-3):72-84 (2007)
to & Angiogenesis Animals Blood Endothelial Factors Growth Humans Inhibitors Laboratories Neoplasms Neovascularization Pathologic Research Vascular Vessels antagonists blood cells drug inhibitors pathology supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Sunitinib efficacy against advanced renal cell carcinoma
R. J. Motzer, M. D. Michaelson, J. Rosenberg, R. M. Bukowski, B. D. Curti, D. J. George, G. R. Hudes, B. G. Redman, K. A. Margolin, and G. Wilding J.Urol. 178(5):1883-1887 (2007)
to & Administration Adult Aged Agents Antineoplastic Carcinoma Cell Disease Disease-Free Female Follow-Up Humans Indoles Kidney Laboratories Male Method Middle Neoplasm Neoplasms Oral Outcome Progression Pyrroles Rate Renal Research Retrospective Single-Blind Staging States Studies Survival Treatment Tyrosine United administration dosage drug epidemiology methods mortality pathology response therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Surrogate biomarkers in evaluating response to anti-angiogenic agents: focus on sunitinib
S. E. Deprimo, and C. Bello Ann.Oncol (2007)
to Angiogenesis Biological Cells Endothelial Growth Humans Indoles Inhibitors Laboratories Markers Neoplasms Neovascularization Pathologic Proteins Pyrroles Research Tumor blood cells diagnosis drug effects metabolism methods pathology pharmacology protein response supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Vascular endothelial growth factor-D and its receptor VEGFR-3: two novel independent prognostic markers in gastric adenocarcinoma
S. Juttner, C. Wissmann, T. Jons, M. Vieth, J. Hertel, S. Gretschel, P. M. Schlag, W. Kemmner, and M. Hocker J.Clin.Oncol. 24(2):228-240 (2006)
to 80 Adenocarcinoma Adult Aged Antibodies C Cell Chemistry D Disease-Free Endothelial Factor Growth Humans Immunohistochemistry Laboratories Line Lymphatic Messenger Metastasis Middle Neoplasms Prognosis RNA Receptor-3 Research Stomach Survival Tumor Vascular analysis and blood genetics identify methods mortality over supply by kanefendt on Feb 5, 2010, 11:28 AM
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VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment
A. Gampel, L. Moss, M. C. Jones, V. Brunton, J. C. Norman, and H. Mellor Blood 108(8):2624-2631 (2006)
to A Active Adult Biological Blood Cell Cells Compartmentation Cultured Endosomes Endothelial Factor GTP-Binding Growth Humans Kinases Laboratories Lysosomes Membrane Plasma Proteins Receptor-2 Recombinant Research Transport Tyrosine Vascular Vessels blood cells cytology drug effects metabolism pharmacology protein rab4 response src-Family by kanefendt on Feb 5, 2010, 11:28 AM
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Notch signaling in the regulation of tumor angiogenesis
A. O. Rehman, and C. Y. Wang Trends Cell Biol. 16(6):293-300 (2006)
to & Agents Angiogenesis Animals Binding Biological Blood Carcinogens Cells Endothelial Genes Humans Inducing Inhibitors Laboratories Ligands Models Neoplasms Neovascularization Notch Pathologic Receptors Signal Suppressor Transduction Tumor Vessels blood cells development growth metabolism physiology supply therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Biomarker method validation in anticancer drug development
J. Cummings, T. H. Ward, A. Greystoke, M. Ranson, and C. Dive Br.J.Pharmacol. 153(4):646-656 (2008)
to & Adherence Agents Animals Antineoplastic Assay Biomarkers Cell Clinical Control Death Drug Enzyme-Linked Europe Evaluation Guideline Guidelines Humans Immunosorbent Keratin-18 Laboratories Mass Pharmacological Preclinical Proteins Quality Reproducibility Research Results Spectrometry Terminology Topic Trials analysis as drug effects jurisprudence legislation methods of pharmacology protein standards therapeutic use by kanefendt on Feb 5, 2010, 11:28 AM
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Tumoural expression and circulating level of VEGFR-3 Flt-4 in metastatic melanoma patients: correlation with clinical parameters and outcome
R. Mouawad, J. P. Spano, E. Comperat, F. Capron, and D. Khayat Eur.J.Cancer 45(8):1407-1414 (2009)
to Assay C Endothelial Enzyme-Linked Factor France Growth Immunosorbent Laboratories Medical Oncology Prognosis Research Vascular cells by kanefendt on Feb 5, 2010, 11:28 AM
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Recommendations for the validation of immunoassays used for detection of host antibodies against biotechnology products
G. Shankar, V. Devanarayan, L. Amaravadi, Y. C. Barrett, R. Bowsher, D. Finco-Kent, M. Fiscella, B. Gorovits, S. Kirschner, M. Moxness, T. Parish, V. Quarmby, H. Smith, W. Smith, L. A. Zuckerman, and E. Koren J.Pharm.Biomed.Anal. 48(5):1267-1281 (2008)
to Antibodies Human Humans Immunoassay Laboratories Proteins Research methods pharmacology protein response toxicity by kanefendt on Feb 5, 2010, 11:28 AM
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Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
T. Tammela, G. Zarkada, E. Wallgard, A. Murtomaki, S. Suchting, M. Wirzenius, M. Waltari, M. Hellstrom, T. Schomber, R. Peltonen, C. Freitas, A. Duarte, H. Isoniemi, P. Laakkonen, G. Christofori, S. Yla-Herttuala, M. Shibuya, B. Pytowski, A. Eichmann, C. Betsholtz, and K. Alitalo Nature 454(7204):656-660 (2008)
to & Adult Angiogenesis Animals Antibodies BALB Blood C Cell Cells Dipeptides Down-Regulation Endothelial Endothelium Expression Factor Factors Female Gene Growth Humans Inbred Inhibitors Laboratories Ligands Line Lymphangiogenesis Mice Monoclonal Neoplasms Neoplastic Neovascularization Notch Pathologic Proliferation Receptor-3 Receptors Regulation Research Signal Transduction Transgenic Tumor Tyrosine Vascular Vessels antagonists blood cells drug effects genetics inhibitors metabolism pharmacology supply therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Harmonization of strategies for the validation of quantitative analytical procedures: A SFSTP proposal Part IV. Examples of application
P. Hubert, J. J. Nguyen-Huu, B. Boulanger, E. Chapuzet, N. Cohen, P. A. Compagnon, W. Dewe, M. Feinberg, M. Laurentie, N. Mercier, G. Muzard, L. Valat, and E. Rozet J.Pharm.Biomed.Anal. 48(3):760-771 (2008)
to Chemistry Chromatography Control Laboratories Quality RANGE Research methods by kanefendt on Feb 5, 2010, 11:28 AM
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Molecular biology and pathology of lymphangiogenesis
T. Karpanen, and K. Alitalo Annu.Rev.Pathol. (2008)
to Animal Animals Biological Biology Developmental Endothelial Endothelium Expression Factors Gene Growth Humans Laboratories Lymphangiogenesis Lymphatic Lymphedema Markers Mice Models Molecular Regulation Research System Vascular Vessels cytology genetics metabolism methods pathology by kanefendt on Feb 5, 2010, 11:28 AM
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VEGFs, receptors and angiogenesis
T. Veikkola, and K. Alitalo Semin.Cancer Biol. 9(3):211-220 (1999)
to A Animals Blood Endothelial Factor Factors Growth Humans Kinase Kinases Laboratories Lymphokines Neoplasms Neovascularization Pathologic Physiologic Protein-Tyrosine Receptor Receptors Research Vascular Vessels blood etiology physiology supply by kanefendt on Feb 5, 2010, 11:28 AM
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Proteolytic processing regulates receptor specificity and activity of VEGF-C
V. Joukov, T. Sorsa, V. Kumar, M. Jeltsch, L. Claesson-Welsh, Y. Cao, O. Saksela, N. Kalkkinen, and K. Alitalo EMBO J. 16(13):3898-3911 (1997)
to Acid Amino Animals Antibodies C Cells Cos Cultured Data Dimerization Disulfides Endopeptidases Endothelial Endothelium Factor Factors Growth Humans Kinase Kinases Laboratories Molecular Phosphorylation Post-Translational Processing Protein Protein-Tyrosine Rabbits Receptor Receptors Research Sequence Tumor Tyrosine Vascular biosynthesis cells genetics metabolism secretion by kanefendt on Feb 5, 2010, 11:28 AM
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Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets
R. Mohle, D. Green, M. A. Moore, R. L. Nachman, and S. Rafii Proc.Natl.Acad.Sci.U.S.A 94(2):663-668 (1997)
to A Alternative Blood Cell Cells Complex Cultured Cytokines Endothelial Endothelium Expression Factor Factors GPIIb-IIIa Gene Glycoprotein Growth Hematopoiesis Human Humans Immunohistochemistry Kinase Kinases Laboratories Line Lymphokines Megakaryocytes Neovascularization Physiologic Platelet Platelets Protein-Tyrosine Receptor Receptors Research Splicing Thrombin Vascular analysis cells cytology genetics metabolism pharmacology protein secretion by kanefendt on Feb 5, 2010, 11:28 AM
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Optimizing the use of biomarkers, surrogate endpoints, and clinical endpoints for more efficient drug development
W. A. Colburn J.Clin.Pharmacol. 40(12 Pt 2):1419-1427 (2000)
to Biological Design Dose-Response Drug Factors Forecasting Humans Laboratories Markers Pharmacokinetics Relationship Reproducibility Results Time analysis drug of therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Regulation of angiogenesis via vascular endothelial growth factor receptors
T. Veikkola, M. Karkkainen, L. Claesson-Welsh, and K. Alitalo Cancer Res. 60(2):203-212 (2000)
to A Animals Endothelial Factor Factors Growth Humans Kinase Kinases Laboratories Lymphokines Neoplasms Neovascularization Pathologic Physiologic Protein-Tyrosine Receptor Receptors Research Vascular blood physiology physiopathology supply by kanefendt on Feb 5, 2010, 11:28 AM
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Human anti-animal antibody interferences in immunological assays
L. J. Kricka Clin.Chem. 45(7):942-956 (1999)
to Animals Antibodies Antibody Body False Fluids Human Humans Immunoassay Laboratories Mice Monoclonal Negative Population Positive RANGE Reactions Specificity analysis immunology methods pathology response standards therapy by kanefendt on Feb 5, 2010, 11:28 AM
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