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Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins
Samuel Deprimo
,
Carlo Bello
,
John Smeraglia
,
Charles Baum
,
Dominic Spinella
,
Brian Rini
,
M. Dror Michaelson
, and
Robert Motzer
Journal of Translational Medicine
5(1):32
(
2007
)
to
Carcinoma
Disease
Placenta
Progression
Proteins
Tyrosine
analysis
protein
response
therapy
by
kanefendt
on
Feb 5, 2010, 11:28 AM
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(0)
Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy
J. M. Ebos
,
C. R. Lee
,
J. G. Christensen
,
A. J. Mutsaers
, and
R. S. Kerbel
Proc.Natl.Acad.Sci.U.S.A
104(43):17069-17074
(
2007
)
to
&
A
Administration
Agents
Angiogenesis
Animals
Antineoplastic
Antitumor
Assays
Blood
Cell
Dose-Response
Drug
Endothelial
Factor
Female
Growth
Humans
Hypoxia
Indoles
Inducing
Line
Mice
Model
Neoplasms
Organ
Outcome
Placenta
Pregnancy
Proteins
Pyrroles
RANGE
Receptor-2
Relationship
Research
Schedule
Scid
Specificity
Treatment
Tumor
Tyrosine
Vascular
Xenograft
administration
blood
dosage
drug
effects
metabolism
pathology
pharmacology
protein
response
therapy
toxicity
by
kanefendt
on
Feb 5, 2010, 11:28 AM
URL
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(0)
Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis
M. Shibuya
, and
L. Claesson-Welsh
Exp.Cell Res.
312(5):549-560
(
2006
)
to
Aging
Animals
Cell
Cells
Development
Division
Embryonic
Endothelial
Endothelium
Factor
Growth
Human
Humans
Japan
Ligands
Lymphangiogenesis
Lymphatic
Lymphedema
Neovascularization
Pathologic
Physiologic
Placenta
Receptor-1
Receptor-2
Research
Signal
System
Transduction
Tyrosine
Vascular
Vertebrates
cells
cytology
genetics
physiology
physiopathology
response
by
kanefendt
on
Feb 5, 2010, 11:28 AM
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(0)
Evidence for the existence of a novel pregnancy-associated soluble variant of the vascular endothelial growth factor receptor, Flt-1
R. E. Banks
,
M. A. Forbes
,
J. Searles
,
D. Pappin
,
B. Canas
,
D. Rahman
,
S. Kaufmann
,
C. E. Walters
,
A. Jackson
,
P. Eves
,
G. Linton
,
J. Keen
,
J. J. Walker
, and
P. J. Selby
Mol Hum.Reprod.
4(4):377-386
(
1998
)
to
&
A
Acid
Amino
Binding
Blood
Cells
Chain
Chemistry
Data
Endothelial
Factor
Factors
Female
Fetal
Growth
Human
Humans
Kinase
Kinases
Lymphokines
Male
Molecular
Placenta
Polymerase
Pregnancy
Protein
Protein-Tyrosine
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Proto-Oncogene
Reaction
Receptor
Receptor-1
Research
Reverse
Sequence
Solubility
Transcriptase
Umbilical
Vascular
Veins
Weight
blood
cells
cytology
identify
isolation
metabolism
protein
purification
by
kanefendt
on
Feb 5, 2010, 11:28 AM
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(0)
FLT4, a novel class III receptor tyrosine kinase in chromosome 5q33-qter
O. Aprelikova
,
K. Pajusola
,
J. Partanen
,
E. Armstrong
,
R. Alitalo
,
S. K. Bailey
,
J. McMahon
,
J. Wasmuth
,
K. Huebner
, and
K. Alitalo
Cancer Res.
52(3):746-748
(
1992
)
to
5
Acid
Adult
Amino
Banding
Blotting
Cell
Chain
Chromosome
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Data
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Human
Humans
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Northern
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Organ
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Polymerase
Protein-Tyrosine
RNA
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Research
Sequence
Specificity
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analysis
cells
genetics
by
kanefendt
on
Feb 5, 2010, 11:28 AM
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