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Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy
J. M. Ebos, C. R. Lee, J. G. Christensen, A. J. Mutsaers, and R. S. Kerbel Proc.Natl.Acad.Sci.U.S.A 104(43):17069-17074 (2007)
to & A Administration Agents Angiogenesis Animals Antineoplastic Antitumor Assays Blood Cell Dose-Response Drug Endothelial Factor Female Growth Humans Hypoxia Indoles Inducing Line Mice Model Neoplasms Organ Outcome Placenta Pregnancy Proteins Pyrroles RANGE Receptor-2 Relationship Research Schedule Scid Specificity Treatment Tumor Tyrosine Vascular Xenograft administration blood dosage drug effects metabolism pathology pharmacology protein response therapy toxicity by kanefendt on Feb 5, 2010, 11:28 AM
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Increased plasma vascular endothelial growth factor VEGF as a surrogate marker for optimal therapeutic dosing of VEGF receptor-2 monoclonal antibodies
G. Bocci, S. Man, S. K. Green, G. Francia, J. M. Ebos, J. M. Du Manoir, A. Weinerman, U. Emmenegger, L. Ma, P. Thorpe, A. Davidoff, J. Huber, D. J. Hicklin, and R. S. Kerbel Cancer Res. 64(18):6616-6625 (2004)
to & A Adenocarcinoma Administration Angiogenesis Animals Antibodies Antineoplastic Biological Blood Cell Chemotherapy Colorectal Combined Drug Endothelial Factor Growth Human Humans Inhibitors Line Male Markers Messenger Mice Modality Monoclonal Neoplasms Neovascularization Nude Pathologic Platelets Prostatic Protocols RNA Receptor-2 Research Schedule Scid Therapy Tumor Vascular administration biosynthesis blood dosage genetics immunology metabolism protein supply therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels
Y. He, I. Rajantie, K. Pajusola, M. Jeltsch, T. Holopainen, S. Yla-Herttuala, T. Harding, K. Jooss, T. Takahashi, and K. Alitalo Cancer Res. 65(11):4739-4746 (2005)
to & Adenoviridae Animals Antitumor Assays Cell Cells Endothelial Endothelium Factor Fusion Genetic Growth Humans Immunoglobulins Laboratories Line Lung Lymph Lymphangiogenesis Lymphatic Metastasis Mice Model Neoplasm Neoplasms Neovascularization Nodes Pathologic Proteins Receptor-3 Recombinant Research Scid Signal Staging Transduction Tumor Vascular Vectors Vessels Xenograft administration antagonists cells control dosage genetics inhibitors pathology physiology prevention protein therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth
T. Karpanen, M. Egeblad, M. J. Karkkainen, H. Kubo, S. Yla-Herttuala, M. Jaattela, and K. Alitalo Cancer Res. 61(5):1786-1790 (2001)
to & Animals Blood Breast C Carcinoma Cell Division Endothelial Factor Factors Female Fusion Growth Heterologous Human Humans Immunoglobulins Kinase Kinases Laboratories Lymphangiogenesis Lymphatic Mice Neoplasm Neoplasms Neovascularization Pathologic Protein-Tyrosine Proteins Receptor Receptor-3 Receptors Recombinant Research Scid System Transfection Transplantation Vascular Vessels antagonists biosynthesis blood cells genetics inhibitors metabolism pathology physiology physiopathology protein supply by kanefendt on Feb 5, 2010, 11:28 AM
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Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
Y. He, K. Kozaki, T. Karpanen, K. Koshikawa, S. Yla-Herttuala, T. Takahashi, and K. Alitalo J.Natl.Cancer Inst. 94(11):819-825 (2002)
to & Animals Antibodies Blotting C Cell Cells Cultured D Division Endothelial Expression Factor Factors Female Gene Growth Human Humans Kinase Kinases Laboratories Line Lung Lymph Lymphangiogenesis Lymphatic Metastasis Mice Neoplasm Neoplasms Neoplastic Nodes Protein-Tyrosine RNA Receptor Receptor-3 Receptors Regulation Research Scid Signal Time Transduction Transfection Transplantation Tumor Vascular Vessels Western antagonists blood cells control genetics immunology inhibitors metabolism methods pathology prevention protein secondary supply by kanefendt on Feb 5, 2010, 11:28 AM
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