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Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis
A. Y. Debrah, S. Mand, S. Specht, Y. Marfo-Debrekyei, L. Batsa, K. Pfarr, J. Larbi, B. Lawson, M. Taylor, O. Adjei, and A. Hoerauf PLoS.Pathog. 2(9):e92 (2006)
to & Adult Aged Animals C Data Doxycycline Elephantiasis Endothelial Factor Female Filarial Filaricides Growth Humans Hydrocele Intercellular Lymphatic Lymphedema Male Microfilaria Middle Molecular Outcome Parasitemia Peptides Plasma Proteins Receptor-3 Research Sequence Signaling System Testicular Testis Treatment Vascular Vessels Wolbachia and antagonists blood drug effects immunology inhibitors isolation parasitology pathology physiology protein purification therapeutic therapy ultrasonography use by kanefendt on Feb 5, 2010, 11:28 AM
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Evidence for the existence of a novel pregnancy-associated soluble variant of the vascular endothelial growth factor receptor, Flt-1
R. E. Banks, M. A. Forbes, J. Searles, D. Pappin, B. Canas, D. Rahman, S. Kaufmann, C. E. Walters, A. Jackson, P. Eves, G. Linton, J. Keen, J. J. Walker, and P. J. Selby Mol Hum.Reprod. 4(4):377-386 (1998)
to & A Acid Amino Binding Blood Cells Chain Chemistry Data Endothelial Factor Factors Female Fetal Growth Human Humans Kinase Kinases Lymphokines Male Molecular Placenta Polymerase Pregnancy Protein Protein-Tyrosine Proteins Proto-Oncogene Reaction Receptor Receptor-1 Research Reverse Sequence Solubility Transcriptase Umbilical Vascular Veins Weight blood cells cytology identify isolation metabolism protein purification by kanefendt on Feb 5, 2010, 11:28 AM
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Proteolytic processing regulates receptor specificity and activity of VEGF-C
V. Joukov, T. Sorsa, V. Kumar, M. Jeltsch, L. Claesson-Welsh, Y. Cao, O. Saksela, N. Kalkkinen, and K. Alitalo EMBO J. 16(13):3898-3911 (1997)
to Acid Amino Animals Antibodies C Cells Cos Cultured Data Dimerization Disulfides Endopeptidases Endothelial Endothelium Factor Factors Growth Humans Kinase Kinases Laboratories Molecular Phosphorylation Post-Translational Processing Protein Protein-Tyrosine Rabbits Receptor Receptors Research Sequence Tumor Tyrosine Vascular biosynthesis cells genetics metabolism secretion by kanefendt on Feb 5, 2010, 11:28 AM
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Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
M. J. Karkkainen, R. E. Ferrell, E. C. Lawrence, M. A. Kimak, K. L. Levinson, M. A. McTigue, K. Alitalo, and D. N. Finegold Nat.Genet. 25(2):153-159 (2000)
to 5 Activation Alleles Animals C Cell Chemistry Chromosomes Data Dominant Endothelial Enzyme Factor Factors Female Fusion Genes Growth Half-Life Human Humans Infant Kinase Kinases Laboratories Line Lymphedema Male Mice Missense Models Molecular Mutation Newborn Pair Pedigree Phosphorylation Protein Protein-Tyrosine Proteins Receptor Receptor-3 Receptors Recombinant Research Sequence Signal Stability Structure Surface Transcriptional Transduction Tyrosine Vascular congenital drug effects genetics metabolism pharmacology protein secondary by kanefendt on Feb 5, 2010, 11:28 AM
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Possible participation of autocrine and paracrine vascular endothelial growth factors in hypoxia-induced proliferation of endothelial cells and pericytes
M. Nomura, S. Yamagishi, S. Harada, Y. Hayashi, T. Yamashima, J. Yamashita, and H. Yamamoto J.Biol.Chem. 270(47):28316-28324 (1995)
to & A Animals Antisense Base Cattle Cell Cells Chain Cultured DNA Data Division Dna Endothelial Endothelium Factor Factors Growth Human Humans Hypoxia Japan Kinase Kinases Kinetics Lymphokines Messenger Microcirculation Mitogen Molecular Muscle Oligonucleotide Oligonucleotides Oxygen Polymerase Primers Probes Protein-Tyrosine Proteins Proto-Oncogene RNA Reaction Receptor Receptor-1 Receptors Replication Research Retina Retinal Sequence Smooth Tyrosine Umbilical Vascular Veins Vessels analysis antagonists biosynthesis cells cytology drug effects inhibitors pharmacology physiology protein by kanefendt on Feb 5, 2010, 11:28 AM
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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
J. A. Forsythe, B. H. Jiang, N. V. Iyer, F. Agani, S. W. Leung, R. D. Koos, and G. L. Semenza Mol.Cell Biol. 16(9):4604-4613 (1996)
to (Genetics) 1 40 A Acid Alignment Animals Base Binding Carcinoma Cell Cells Chemistry Cultured DNA-Binding Data Endothelial Expression Factor Factors Fusion Gene Genes Genetic Growth Hepatocellular Homology Human Humans Hypoxia Hypoxia-Inducible Liver Lymphokines Mice Molecular Neoplasms Nuclear Nucleic Promoter Proteins Rats Recombinant Regions Regulation Reporter Research Sequence Simian Subunit Transcription Transfection Tumor Vascular alpha biosynthesis cells genetics metabolism pathology physiology protein response virus by kanefendt on Feb 5, 2010, 11:28 AM
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FLT4, a novel class III receptor tyrosine kinase in chromosome 5q33-qter
O. Aprelikova, K. Pajusola, J. Partanen, E. Armstrong, R. Alitalo, S. K. Bailey, J. McMahon, J. Wasmuth, K. Huebner, and K. Alitalo Cancer Res. 52(3):746-748 (1992)
to 5 Acid Adult Amino Banding Blotting Cell Chain Chromosome Chromosomes Data Dna Homology Human Humans Kidney Kinase Kinases Leukemia Lung Messenger Molecular Northern Nucleic Organ Pair Placenta Polymerase Protein-Tyrosine RNA Reaction Receptors Research Sequence Specificity Surface Tyrosine analysis cells genetics by kanefendt on Feb 5, 2010, 11:28 AM
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FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines
K. Pajusola, O. Aprelikova, J. Korhonen, A. Kaipainen, L. Pertovaara, R. Alitalo, and K. Alitalo Cancer Res. 52(20):5738-5743 (1992)
to & Acid Amino Base Blood Cell Cells Chemistry Cloning Conformation Data Development Differentiation Distribution Dna Down-Regulation Embryonic Endothelial Epithelial Expression Factor Fetal Gene Growth Homology Human Humans Immunoglobulins Kinase Kinases Leukemia Line Lung Molecular Nucleic Protein Protein-Tyrosine Receptor-3 Receptors Research Sequence Species Specificity Surface Teratoma Tissue Tyrosine Vascular Vessels and blood cells genetics isolation pathology protein purification by kanefendt on Feb 5, 2010, 11:28 AM
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Receptor protein-tyrosine kinases and their signal transduction pathways
Geer P. van der, T. Hunter, and R. A. Lindberg Annu.Rev.Cell Biol. (1994)
to Acid Alignment Amino Animals Biological Conformation Data Factor Family Growth Homology Humans Kinase Kinases Laboratories Models Molecular Multigene Phosphorylation Post-Translational Processing Protein Protein-Tyrosine Receptor Receptors Sequence Signal Substances Transduction classification genetics physiology by kanefendt on Feb 5, 2010, 11:28 AM
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Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification
S. E. Deprimo, L. M. Wong, D. B. Khatry, S. L. Nicholas, W. C. Manning, B. D. Smolich, A. M. O'Farrell, and J. M. Cherrington BMC.Cancer (2003)
to & 9 Aged Analysis Angiogenesis Antigens Array Biological Biopsy CD CD24 Chain Chemistry Clinical Colorectal Expression Female Gene Glycoproteins Human Humans III Indoles Inhibitors Kinase Kinases Lactoferrin Leukocytes Male Markers Matrix Membrane Metalloproteinase Metastasis Middle Mononuclear Neoplasm Neoplasms Neoplastic Oligonucleotide Phase Polymerase Predictive Profiling Protein-Tyrosine Pyrroles Reaction Regulation Research Reverse Sequence Tests Topic Transcriptase Trials Tumor Tyrosine Value analysis antagonists as blood cells drug genetics identify inhibitors metabolism methods of protein response therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells
K. Spiekermann, K. Bagrintseva, R. Schwab, K. Schmieja, and W. Hiddemann Clin.Cancer Res. 9(6):2140-2150 (2003)
to 3 Acid Activation Acute Amino Cell DNA-Binding Data Enzyme Factor Human Humans Indoles Kinase Kinases Leukemia Milk Mitogen-Activated Molecular Mutation Myeloid Neoplastic Phenotype Phosphorylation Protein Protein-Tyrosine Proteins Proto-Oncogene Receptor Research STAT3 STAT5 Sequence Trans-Activators Transcription Transformation Tyrosine cells fms-Like metabolism pathology pharmacology physiology protein response therapy by kanefendt on Feb 5, 2010, 11:28 AM
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