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Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization
D. Fukumura, and R. K. Jain Microvasc.Res. 74(2-3):72-84 (2007)
to & Angiogenesis Animals Blood Endothelial Factors Growth Humans Inhibitors Laboratories Neoplasms Neovascularization Pathologic Research Vascular Vessels antagonists blood cells drug inhibitors pathology supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Molecular mechanisms of lymphatic vascular development
T. Makinen, C. Norrmen, and T. V. Petrova Cell Mol.Life Sci. 64(15):1915-1929 (2007)
to A Angiopoietins Animals Biological Cells Cultured Endothelial Factor Growth Human Humans Inflammation Lymphangiogenesis Lymphatic Lymphedema Models Proteins Receptors Research Substances TIE Transport Vascular Vesicular Vessels analysis cells cytology physiology protein by kanefendt on Feb 5, 2010, 11:28 AM
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VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment
A. Gampel, L. Moss, M. C. Jones, V. Brunton, J. C. Norman, and H. Mellor Blood 108(8):2624-2631 (2006)
to A Active Adult Biological Blood Cell Cells Compartmentation Cultured Endosomes Endothelial Factor GTP-Binding Growth Humans Kinases Laboratories Lysosomes Membrane Plasma Proteins Receptor-2 Recombinant Research Transport Tyrosine Vascular Vessels blood cells cytology drug effects metabolism pharmacology protein rab4 response src-Family by kanefendt on Feb 5, 2010, 11:28 AM
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Notch signaling in the regulation of tumor angiogenesis
A. O. Rehman, and C. Y. Wang Trends Cell Biol. 16(6):293-300 (2006)
to & Agents Angiogenesis Animals Binding Biological Blood Carcinogens Cells Endothelial Genes Humans Inducing Inhibitors Laboratories Ligands Models Neoplasms Neovascularization Notch Pathologic Receptors Signal Suppressor Transduction Tumor Vessels blood cells development growth metabolism physiology supply therapy by kanefendt on Feb 5, 2010, 11:28 AM
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The role of the VEGF-C/VEGFR-3 axis in cancer progression
J. L. Su, C. J. Yen, P. S. Chen, S. E. Chuang, C. C. Hong, I. H. Kuo, H. Y. Chen, M. C. Hung, and M. L. Kuo Br.J.Cancer 96(4):541-545 (2007)
to C Cells Disease Endothelial Factor Growth Human Humans Leukemia Lymphangiogenesis Lymphatic Neoplasms Progression Receptor-3 Research Vascular Vessels cells metabolism pathology physiopathology by kanefendt on Feb 5, 2010, 11:28 AM
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Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis
A. Y. Debrah, S. Mand, S. Specht, Y. Marfo-Debrekyei, L. Batsa, K. Pfarr, J. Larbi, B. Lawson, M. Taylor, O. Adjei, and A. Hoerauf PLoS.Pathog. 2(9):e92 (2006)
to & Adult Aged Animals C Data Doxycycline Elephantiasis Endothelial Factor Female Filarial Filaricides Growth Humans Hydrocele Intercellular Lymphatic Lymphedema Male Microfilaria Middle Molecular Outcome Parasitemia Peptides Plasma Proteins Receptor-3 Research Sequence Signaling System Testicular Testis Treatment Vascular Vessels Wolbachia and antagonists blood drug effects immunology inhibitors isolation parasitology pathology physiology protein purification therapeutic therapy ultrasonography use by kanefendt on Feb 5, 2010, 11:28 AM
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A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap
F. T. Wu, M. O. Stefanini, Gabhann F. Mac, and A. S. Popel PLoS.One. 4(4):e5108 (2009)
to A Binding Biological Biology Capillaries Dimerization Endothelial Factor Growth Human Humans Ligands Lymphatic Models Muscle Plasma Receptor-1 Research Skeletal States Systems Tyrosine United Vascular Vessels metabolism physiology protein therapy ultrastructure by kanefendt on Feb 5, 2010, 11:28 AM
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Angiogenesis induced by hVEGF165 gene controlled by hypoxic response elements in rabbit ischemia myocardium
H. Dong, Q. Wang, Y. Zhang, B. Jiang, X. Xu, and Z. Zhang Exp.Biol.Med.Maywood. 234(12):1417-1424 (2009)
to 1 A Actins Animals Antigens Blood CD31 Dependovirus Elements Endothelial Expression Factor Gene Genetic Growth Heart Human Humans Hypoxia-Inducible Immunohistochemistry Ischemia Myocardial Myocardium Neovascularization Physiologic Rabbits Regulation Research Response Subunit Therapy Transduction Vascular Vessels alpha biosynthesis blood genetics pathology protein response therapy by kanefendt on Feb 5, 2010, 11:28 AM
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High VEGFR-3-positive circulating lymphatic/vascular endothelial progenitor cell level is associated with poor prognosis in human small cell lung cancer
K. Bogos, F. Renyi-Vamos, J. Dobos, I. Kenessey, J. Tovari, J. Timar, J. Strausz, G. Ostoros, W. Klepetko, H. J. Ankersmit, G. Lang, M. A. Hoda, P. Nierlich, and B. Dome Clin.Cancer Res. 15(5):1741-1746 (2009)
to Adult Aged Antibodies Assay Bone C Capillaries Carcinoma Case-Control Cell Cells Cytometry Disease Endothelial Enzyme-Linked Factor Female Flow Follow-Up Growth Human Humans Immunosorbent Lung Lymphatic Male Marrow Metastasis Middle Neoplasms Population Prognosis Progression Rate Receptor-3 Research Small Stem Studies Survival Vascular Vessels blood cells metabolism pathology by kanefendt on Feb 5, 2010, 11:28 AM
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Role of endothelial progenitor cells in breast cancer angiogenesis: from fundamental research to clinical ramifications
X. Le Bourhis, R. Romon, and H. Hondermarck Breast Cancer Res.Treat. (2009)
to Blood Bone France Marrow Research Vessels blood cells by kanefendt on Feb 5, 2010, 11:28 AM
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Endothelial VEGFR-3 expression in colorectal carcinomas is associated with hematogenous metastasis
C. Jayasinghe, N. Simiantonaki, R. Michel-Schmidt, and C. J. Kirkpatrick Oncol.Rep. 22(5):1093-1100 (2009)
to Antibody Assay Blood Carcinoma Cell Cells Colon Colorectal Cytometry Endothelial Endothelium Enzyme-Linked Factor Flow Fluorescent Growth Human Humans Hypoxia Immunoenzyme Immunohistochemistry Immunosorbent Lymphatic Metastasis Neoplasm Neoplasms Neovascularization Pathologic Prognosis Receptor-3 Technique Techniques Vascular Vessels blood cells metabolism pathology protein supply by kanefendt on Feb 5, 2010, 11:28 AM
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Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
T. Tammela, G. Zarkada, E. Wallgard, A. Murtomaki, S. Suchting, M. Wirzenius, M. Waltari, M. Hellstrom, T. Schomber, R. Peltonen, C. Freitas, A. Duarte, H. Isoniemi, P. Laakkonen, G. Christofori, S. Yla-Herttuala, M. Shibuya, B. Pytowski, A. Eichmann, C. Betsholtz, and K. Alitalo Nature 454(7204):656-660 (2008)
to & Adult Angiogenesis Animals Antibodies BALB Blood C Cell Cells Dipeptides Down-Regulation Endothelial Endothelium Expression Factor Factors Female Gene Growth Humans Inbred Inhibitors Laboratories Ligands Line Lymphangiogenesis Mice Monoclonal Neoplasms Neoplastic Neovascularization Notch Pathologic Proliferation Receptor-3 Receptors Regulation Research Signal Transduction Transgenic Tumor Tyrosine Vascular Vessels antagonists blood cells drug effects genetics inhibitors metabolism pharmacology supply therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Circulating lymphangiogenic growth factors in gastrointestinal solid tumors, could they be of any clinical significance?
T. D. Tsirlis, G. Papastratis, K. Masselou, C. Tsigris, A. Papachristodoulou, A. Kostakis, and N. I. Nikiteas World J.Gastroenterol. 14(17):2691-2701 (2008)
to Biological C Chain Colorectal D Endothelial Esophageal Factor Gastrointestinal Growth Human Humans Immunohistochemistry Inflammation Ligands Lymphangiogenesis Lymphatic Markers Metastasis Neoplasm Neoplasms Polymerase Predictive Prognosis Reaction Receptor-3 Staging Stomach System Tests Tumor Value Vascular Vessels blood metabolism mortality of pathology physiopathology surgery by kanefendt on Feb 5, 2010, 11:28 AM
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Molecular biology and pathology of lymphangiogenesis
T. Karpanen, and K. Alitalo Annu.Rev.Pathol. (2008)
to Animal Animals Biological Biology Developmental Endothelial Endothelium Expression Factors Gene Growth Humans Laboratories Lymphangiogenesis Lymphatic Lymphedema Markers Mice Models Molecular Regulation Research System Vascular Vessels cytology genetics metabolism methods pathology by kanefendt on Feb 5, 2010, 11:28 AM
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Expression of vascular endothelial growth factor-C and its receptor in osteosarcomas
H. R. Park, K. Min, H. S. Kim, W. W. Jung, and Y. K. Park Pathol.Res.Pract. 204(8):575-582 (2008)
to Adolescent Adult Aged Bone C Cell Chain Child Cytoplasm D Endothelial Expression Factor Female Gene Growth Human Humans Immunohistochemistry Line Lymphatic Male Messenger Metastasis Middle Neoplasm Neoplasms Neoplastic Osteosarcoma Polymerase RNA Reaction Receptor-3 Regulation Research Up-Regulation Vascular Vessels cells genetics metabolism pathology protein by kanefendt on Feb 5, 2010, 11:28 AM
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VEGFR-3 expression is restricted to blood and lymphatic vessels in solid tumors
T. V. Petrova, P. Bono, W. Holnthoner, J. Chesnes, B. Pytowski, H. Sihto, P. Laakkonen, P. Heikkila, H. Joensuu, and K. Alitalo Cancer Cell 13(6):554-556 (2008)
to Antibodies Antibody Blood Blotting Cell Cells Chain Chemistry Cytometry Endothelial Factor Flow Growth Humans Immunohistochemistry Line Lymphatic Messenger Neoplasms Northern Polymerase RNA Reaction Receptor-3 Reproducibility Results Reverse Separation Specificity Transcriptase Tumor Vascular Vessels Western analysis blood genetics immunology methods of pathology supply by kanefendt on Feb 5, 2010, 11:28 AM
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VEGFs, receptors and angiogenesis
T. Veikkola, and K. Alitalo Semin.Cancer Biol. 9(3):211-220 (1999)
to A Animals Blood Endothelial Factor Factors Growth Humans Kinase Kinases Laboratories Lymphokines Neoplasms Neovascularization Pathologic Physiologic Protein-Tyrosine Receptor Receptors Research Vascular Vessels blood etiology physiology supply by kanefendt on Feb 5, 2010, 11:28 AM
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Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
D. J. Dumont, L. Jussila, J. Taipale, A. Lymboussaki, T. Mustonen, K. Pajusola, M. Breitman, and K. Alitalo Science 282(5390):946-949 (1998)
to Adult Animals Antigens Blood C CD31 Cardiovascular Cell Chemistry Development Embryo Embryonic Endothelial Endothelium Factor Factors Fetal Gene Growth Hematopoiesis Heterozygote Homozygote Hybridization Immunohistochemistry In Kinase Kinases Ligands Lymphatic Mammalian Mice Neovascularization Physiologic Protein-Tyrosine Receptor Receptor-3 Receptors Research Signal Situ Surface System Targeting Transduction Vascular Vessels analysis and blood embryology genetics physiology supply by kanefendt on Feb 5, 2010, 11:28 AM
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The hemostatic system as a regulator of angiogenesis
T. Browder, J. Folkman, and S. Pirie-Shepherd J.Biol.Chem. 275(3):1521-1524 (2000)
to Aggregation Animals Biological Blood Capillaries Fibrin Fibrinolysis Hemostasis Models Neovascularization Physiologic Platelet Platelets Research Vessels physiology by kanefendt on Feb 5, 2010, 11:28 AM
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VEGF receptor signaling in tumor angiogenesis
G. McMahon Oncologist. (2000)
to & A Angiogenesis Blood Endothelial Factor Factors Growth Human Humans Inhibitors Isoforms Kinase Kinases Lymphokines Metastasis Mitogen Neoplasm Neoplasms Neovascularization Pathologic Protein Protein-Tyrosine Receptor Receptors Signal Transduction Tyrosine Vascular Vessels antagonists blood drug effects inhibitors physiology physiopathology protein supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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