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Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage
N. Henke, R. Schmidt-Ullrich, R. Dechend, J. K. Park, F. Qadri, M. Wellner, M. Obst, V. Gross, R. Dietz, F. C. Luft, C. Scheidereit, and D. N. Muller Circ.Res. 101(3):268-276 (2007)
to & Adhesion Albuminuria Angiotensin Animals Atherosclerosis B Blood C57BL Cardiovascular Cell Cells Chain Chloride Cultured Dietary Diseases Endothelial Ester Expression Factor-alpha Fusion Gene Humans Hypertension I-kappa II III Inbred Inflammation Intercellular Kidney Methyl Mice Models Molecule-1 NF-kappa NG-Nitroarginine Necrosis Nephritis Nitric Organ Oxide Polymerase Pressure Proteins Reaction Receptor Recombinant Regulation Research Reverse Signal Sodium Specificity Synthase TIE-1 Transcriptase Transduction Transgenic Tumor Type Vascular antagonists biosynthesis blood cells complications control etiology genetics inhibitors metabolism physiology physiopathology prevention protein toxicity by kanefendt on Feb 5, 2010, 11:28 AM
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Molecular basis for sunitinib efficacy and future clinical development
S. Faivre, G. Demetri, W. Sargent, and E. Raymond Nat.Rev.Drug Discov. 6(9):734-745 (2007)
to & A Angiogenesis Animals Carcinoma Clinical Design Drug Endothelial Factor France Growth Humans Indoles Inhibitors Kinase Kinases Neoplasm Neoplasms Protein-Tyrosine Pyrroles Receptors Resistance Topic Trials Tyrosine Vascular adverse antagonists as biosynthesis blood drug effects enzymology inhibitors metabolism pharmacology response supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome
M. J. Cuadrado, P. Buendia, F. Velasco, M. A. Aguirre, N. Barbarroja, L. A. Torres, M. Khamashta, and C. Lopez-Pedrera J.Thromb.Haemost. 4(11):2461-2469 (2006)
to & A Adolescent Adult Aged Antibodies Antiphospholipid Cells Cultured Endothelial Enzyme Expression Factor Female Gene Growth Human Humans Imidazoles Inhibitors Kinase Kinases MAP Male Middle Mitogen-Activated Monocytes Phenotype Protein Pyridines Receptor-1 Regulation Research Signaling Syndrome System Thromboplastin Thrombosis Tyrosine Vascular antagonists biosynthesis cells drug effects inhibitors metabolism p38 pathology pharmacology protein by kanefendt on Feb 5, 2010, 11:28 AM
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Identification of ligand-induced proteolytic cleavage and ectodomain shedding of VEGFR-1/FLT1 in leukemic cancer cells
N. Rahimi, T. E. Golde, and R. D. Meyer Cancer Res. 69(6):2607-2614 (2009)
to Amyloid B-Cell C Cell Cells Cytoplasm Diffuse Endothelial Factor Growth Humans Hypertension Kinase Large Ligands Lymphoma Membrane Necrosis Phosphorylation Precursor Protein Receptor-1 Research Secretases Signal Structure Tertiary Transduction Tyrosine Vascular biosynthesis cells enzymology metabolism pathology protein by kanefendt on Feb 5, 2010, 11:28 AM
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Angiogenesis induced by hVEGF165 gene controlled by hypoxic response elements in rabbit ischemia myocardium
H. Dong, Q. Wang, Y. Zhang, B. Jiang, X. Xu, and Z. Zhang Exp.Biol.Med.Maywood. 234(12):1417-1424 (2009)
to 1 A Actins Animals Antigens Blood CD31 Dependovirus Elements Endothelial Expression Factor Gene Genetic Growth Heart Human Humans Hypoxia-Inducible Immunohistochemistry Ischemia Myocardial Myocardium Neovascularization Physiologic Rabbits Regulation Research Response Subunit Therapy Transduction Vascular Vessels alpha biosynthesis blood genetics pathology protein response therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Release of the angiogenic cytokine vascular endothelial growth factor VEGF from platelets: significance for VEGF measurements and cancer biology
R. E. Banks, M. A. Forbes, S. E. Kinsey, A. Stanley, E. Ingham, C. Walters, and P. J. Selby Br.J Cancer 77(6):956-964 (1998)
to A Acid Adult Aged Assay Biological Blood Bone Cells Citrates Collection Edetic Endothelial Enzyme-Linked Factor Factors Female Growth Healing Heparin Humans Immunohistochemistry Immunosorbent Indicators Lymphokines Male Markers Marrow Megakaryocytes Middle Platelets Reagents Reference Research Sensitivity Specificity Specimen Values Vascular Wound and biosynthesis blood cells cytology methods physiology by kanefendt on Feb 5, 2010, 11:28 AM
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Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia
I. Stein, A. Itin, P. Einat, R. Skaliter, Z. Grossman, and E. Keshet Mol.Cell Biol. 18(6):3112-3119 (1998)
to 3T3 A Animals Biosynthesis Cell Cells Cultured Endothelial Factor Factors Growth Humans Hypoxia Lymphokines Messenger Mice Neovascularization Oxygen Pathologic Protein RNA Rats Research Ribosomes Vascular biosynthesis cells genetics identify metabolism protein by kanefendt on Feb 5, 2010, 11:28 AM
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Proteolytic processing regulates receptor specificity and activity of VEGF-C
V. Joukov, T. Sorsa, V. Kumar, M. Jeltsch, L. Claesson-Welsh, Y. Cao, O. Saksela, N. Kalkkinen, and K. Alitalo EMBO J. 16(13):3898-3911 (1997)
to Acid Amino Animals Antibodies C Cells Cos Cultured Data Dimerization Disulfides Endopeptidases Endothelial Endothelium Factor Factors Growth Humans Kinase Kinases Laboratories Molecular Phosphorylation Post-Translational Processing Protein Protein-Tyrosine Rabbits Receptor Receptors Research Sequence Tumor Tyrosine Vascular biosynthesis cells genetics metabolism secretion by kanefendt on Feb 5, 2010, 11:28 AM
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Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose
H. Aviv, and P. Leder Proc.Natl.Acad.Sci.U.S.A 69(6):1408-1412 (1972)
to & 2 Acrylamides Animals Buffers Carcinoma Cell-Free Centrifugation Chromatography Density Dodecyl Electrophoresis Exchange Globins Gradient Ion Krebs Leucine Messenger Neoplasm Nucleotides Polynucleotides Proteins RNA Rabbits Reticulocytes Ribosomal Sodium Sulfate System Thymine Tritium analysis biosynthesis isolation metabolism methods protein purification by kanefendt on Feb 5, 2010, 11:28 AM
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Possible participation of autocrine and paracrine vascular endothelial growth factors in hypoxia-induced proliferation of endothelial cells and pericytes
M. Nomura, S. Yamagishi, S. Harada, Y. Hayashi, T. Yamashima, J. Yamashita, and H. Yamamoto J.Biol.Chem. 270(47):28316-28324 (1995)
to & A Animals Antisense Base Cattle Cell Cells Chain Cultured DNA Data Division Dna Endothelial Endothelium Factor Factors Growth Human Humans Hypoxia Japan Kinase Kinases Kinetics Lymphokines Messenger Microcirculation Mitogen Molecular Muscle Oligonucleotide Oligonucleotides Oxygen Polymerase Primers Probes Protein-Tyrosine Proteins Proto-Oncogene RNA Reaction Receptor Receptor-1 Receptors Replication Research Retina Retinal Sequence Smooth Tyrosine Umbilical Vascular Veins Vessels analysis antagonists biosynthesis cells cytology drug effects inhibitors pharmacology physiology protein by kanefendt on Feb 5, 2010, 11:28 AM
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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
J. A. Forsythe, B. H. Jiang, N. V. Iyer, F. Agani, S. W. Leung, R. D. Koos, and G. L. Semenza Mol.Cell Biol. 16(9):4604-4613 (1996)
to (Genetics) 1 40 A Acid Alignment Animals Base Binding Carcinoma Cell Cells Chemistry Cultured DNA-Binding Data Endothelial Expression Factor Factors Fusion Gene Genes Genetic Growth Hepatocellular Homology Human Humans Hypoxia Hypoxia-Inducible Liver Lymphokines Mice Molecular Neoplasms Nuclear Nucleic Promoter Proteins Rats Recombinant Regions Regulation Reporter Research Sequence Simian Subunit Transcription Transfection Tumor Vascular alpha biosynthesis cells genetics metabolism pathology physiology protein response virus by kanefendt on Feb 5, 2010, 11:28 AM
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Overview of monoclonal antibodies and small molecules targeting the epidermal growth factor receptor pathway in colorectal cancer
L. C. Snyder, I. Astsaturov, and L. M. Weiner Clin.Colorectal Cancer (2005)
to & Administration Amplification Antibodies Approval Binding Colorectal Drug Epidermal Exanthema Factor Food Gene Growth Humans IgG Ligands Medical Molecular Monoclonal Neoplasms Oncology Phosphorylation Prognosis Receptor Receptors Signal Sites States Transduction Tyrosine United Weight and antagonists biosynthesis cells chemically drug induced inhibitors pharmacology physiology physiopathology response therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure
I. Shiojima, K. Sato, Y. Izumiya, S. Schiekofer, M. Ito, R. Liao, W. S. Colucci, and K. Walsh J.Clin.Invest 115(8):2108-2118 (2005)
to & A Angiopoietin-2 Animals Capillaries Cardiomyopathies Cardiomyopathy Dilated Endothelial Expression Factor Failure Gene Growth Heart Human Humans Kinases Mice Myocardium Neovascularization Pathologic Protein-Serine-Threonine Proteins Proto-Oncogene Regulation Remodeling Research Transgenic Vascular Ventricular biosynthesis c-akt development enzymology genetics growth metabolism pathology protein by kanefendt on Feb 5, 2010, 11:28 AM
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Increased plasma vascular endothelial growth factor VEGF as a surrogate marker for optimal therapeutic dosing of VEGF receptor-2 monoclonal antibodies
G. Bocci, S. Man, S. K. Green, G. Francia, J. M. Ebos, J. M. Du Manoir, A. Weinerman, U. Emmenegger, L. Ma, P. Thorpe, A. Davidoff, J. Huber, D. J. Hicklin, and R. S. Kerbel Cancer Res. 64(18):6616-6625 (2004)
to & A Adenocarcinoma Administration Angiogenesis Animals Antibodies Antineoplastic Biological Blood Cell Chemotherapy Colorectal Combined Drug Endothelial Factor Growth Human Humans Inhibitors Line Male Markers Messenger Mice Modality Monoclonal Neoplasms Neovascularization Nude Pathologic Platelets Prostatic Protocols RNA Receptor-2 Research Schedule Scid Therapy Tumor Vascular administration biosynthesis blood dosage genetics immunology metabolism protein supply therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Inhibition of lymphogenous metastasis using adeno-associated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor
J. Lin, A. S. Lalani, T. C. Harding, M. Gonzalez, W. W. Wu, B. Luan, G. H. Tu, K. Koprivnikar, M. J. VanRoey, Y. He, K. Alitalo, and K. Jooss Cancer Res. 65(15):6901-6909 (2005)
to Adenoviridae Animals C Carcinoma Cell Endothelial Factor Female Gene Genetic Growth Human Humans Kidney Line Lung Lymph Lymphangiogenesis Lymphatic Male Melanoma Metastasis Mice Neoplasms Nodes Nude Prostate Prostatic Receptor-3 Renal Techniques Therapy Transfer Tumor Vascular Vectors biosynthesis blood cells genetics immunology methods pathology secondary therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Prediction of active drug plasma concentrations achieved in cancer patients by pharmacodynamic biomarkers identified from the geo human colon carcinoma xenograft model
F. R. Luo, Z. Yang, H. Dong, A. Camuso, K. McGlinchey, K. Fager, C. Flefleh, D. Kan, I. Inigo, S. Castaneda, T. W. Wong, R. A. Kramer, R. Wild, and F. Y. Lee Clin.Cancer Res. 11(15):5558-5565 (2005)
to Agents Animals Antibodies Antigen Antineoplastic Antitumor Assay Assays Biological Carcinoma Cell Chemistry Colonic Enzyme-Linked Epidermal Factor Factors Female G Growth Human Humans Immunoglobulin Immunohistochemistry Immunosorbent Ki-67 Kinase Line MAP Markers Mice Model Monoclonal Neoplasm Neoplasms Nude Pharmacokinetics Phosphorylation Receptor Research Signaling System Time Transplantation Tumor Tyrosine Xenograft analysis biosynthesis drug metabolism methods pathology pharmacology protein response therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in colorectal carcinoma
J. D. White, P. W. Hewett, D. Kosuge, T. McCulloch, B. C. Enholm, J. Carmichael, and J. C. Murray Cancer Res. 62(6):1669-1675 (2002)
to Adenoma Aged Analysis Biological Carcinoma Colorectal Conditions D Endothelial Factor Factors Female Growth Humans Immunohistochemistry Intestinal Kinase Kinases Laboratories Lymphatic Male Markers Mucosa Multivariate Neoplasms Neovascularization Pathologic Precancerous Prognosis Protein-Tyrosine Receptor Receptor-3 Receptors Research Tumor Vascular Vessels analysis biosynthesis blood metabolism pathology supply by kanefendt on Feb 5, 2010, 11:28 AM
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Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth
T. Karpanen, M. Egeblad, M. J. Karkkainen, H. Kubo, S. Yla-Herttuala, M. Jaattela, and K. Alitalo Cancer Res. 61(5):1786-1790 (2001)
to & Animals Blood Breast C Carcinoma Cell Division Endothelial Factor Factors Female Fusion Growth Heterologous Human Humans Immunoglobulins Kinase Kinases Laboratories Lymphangiogenesis Lymphatic Mice Neoplasm Neoplasms Neovascularization Pathologic Protein-Tyrosine Proteins Receptor Receptor-3 Receptors Recombinant Research Scid System Transfection Transplantation Vascular Vessels antagonists biosynthesis blood cells genetics inhibitors metabolism pathology physiology physiopathology protein supply by kanefendt on Feb 5, 2010, 11:28 AM
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A molecular mechanism regulating circadian expression of vascular endothelial growth factor in tumor cells
S. Koyanagi, Y. Kuramoto, H. Nakagawa, H. Aramaki, S. Ohdo, S. Soeda, and H. Shimeno Cancer Res. 63(21):7277-7283 (2003)
to & (Genetics) 1 A Angiogenesis Animals Aryl Cell Circadian Cycle DNA-Binding Drosophila Endothelial Expression Eye Factor Factors Flavoproteins G-Protein-Coupled Gene Genetic Growth Hydrocarbon Hypoxia Hypoxia-Inducible ICR Inbred Inhibitors Invertebrate Japan Male Messenger Mice Neoplastic Nuclear Photoreceptors Promoter Proteins RNA Receptor Receptors Regions Regulation Research Rhythm Subunit Transcription Transfection Translocator Vascular alpha analysis antagonists biosynthesis cells genetics inhibitors metabolism pharmacology physiology protein response therapy by kanefendt on Feb 5, 2010, 11:28 AM
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