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Protein kinase cross-talk: membrane targeting of the beta-adrenergic receptor kinase by protein kinase C
R. Winstel, S. Freund, C. Krasel, E. Hoppe, and M. J. Lohse. Proc Natl Acad Sci U S A 93(5):2105-9 (March 1996)Winstel, R Freund, S Krasel, C Hoppe, E Lohse, M J Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1996 Mar 5;935:2105-9..
R. Winstel, S. Freund, C. Krasel, E. Hoppe, and M. J. Lohse. Proc Natl Acad Sci U S A 93(5):2105-9 (March 1996)Winstel, R Freund, S Krasel, C Hoppe, E Lohse, M J Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1996 Mar 5;935:2105-9..
2 years and 5 months ago
by pharmawuerz
2
AMP-Dependent Acid Activation/drug Amino Animals C/*physiology CHO Cell Compartmentation Cricetinae Cyclic Data Enzyme Epinephrine/pharmacology Humans Kinase Kinases Kinases/*metabolism Line Membrane/enzymology Molecular Peptides/chemistry Phosphorylation Protein Proteins Receptor Recombinant Sequence Signal Transduction alpha-1/*metabolism beta-Adrenergic effects Adrenergic
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Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart
M. Ungerer, G. Parruti, M. Bohm, M. Puzicha, A. DeBlasi, E. Erdmann, and M. J. Lohse. Circ Res 74(2):206-13 (February 1994)Ungerer, M Parruti, G Bohm, M Puzicha, M DeBlasi, A Erdmann, E Lohse, M J Research Support, Non-U.S. Gov't United states Circulation research Circ Res. 1994 Feb;742:206-13..
M. Ungerer, G. Parruti, M. Bohm, M. Puzicha, A. DeBlasi, E. Erdmann, and M. J. Lohse. Circ Res 74(2):206-13 (February 1994)Ungerer, M Parruti, G Bohm, M Puzicha, M DeBlasi, A Erdmann, E Lohse, M J Research Support, Non-U.S. Gov't United states Circulation research Circ Res. 1994 Feb;742:206-13..
2 years and 5 months ago
by pharmawuerz
2
*Arrestins AMP-Dependent Acid Adult Aged Amino Antigens/genetics/*metabolism Blotting, Cardiac Chain Cyclic Data Eye Female Fragments/genetics Genetic Humans Isomerism Kinases Kinases/genetics/*metabolism Low/*metabolism Male Messenger/metabolism Middle Molecular Myocardium/metabolism Output, Peptide Polymerase Protein Proteins/genetics/*metabolism RNA, Reaction Receptor Sequence Transcription, Western beta-Adrenergic
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Activation of beta-adrenergic receptor kinase during myocardial ischemia
M. Ungerer, K. Kessebohm, K. Kronsbein, M. J. Lohse, and G. Richardt. Circ Res 79(3):455-60 (September 1996)Ungerer, M Kessebohm, K Kronsbein, K Lohse, M J Richardt, G In Vitro Research Support, Non-U.S. Gov't United states Circulation research Circ Res. 1996 Sep;793:455-60..
M. Ungerer, K. Kessebohm, K. Kronsbein, M. J. Lohse, and G. Richardt. Circ Res 79(3):455-60 (September 1996)Ungerer, M Kessebohm, K Kronsbein, K Lohse, M J Richardt, G In Vitro Research Support, Non-U.S. Gov't United states Circulation research Circ Res. 1996 Sep;793:455-60..
2 years and 5 months ago
by pharmawuerz
2
*Arrestins AMP-Dependent Animals Base Cyclic Data Eye Ischemia/*metabolism Kinases Kinases/genetics/*metabolism Male Messenger/metabolism Molecular Myocardial Probes Protein Proteins/metabolism RNA, Rats Receptor Sequence Wistar beta-Adrenergic beta/metabolism Adrenergic
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Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart
M. Ungerer, M. Bohm, J. S. Elce, E. Erdmann, and M. J. Lohse. Circulation 87(2):454-63 (February 1993)Ungerer, M Bohm, M Elce, J S Erdmann, E Lohse, M J In Vitro Research Support, Non-U.S. Gov't United states Circulation Circulation. 1993 Feb;872:454-63..
M. Ungerer, M. Bohm, J. S. Elce, E. Erdmann, and M. J. Lohse. Circulation 87(2):454-63 (February 1993)Ungerer, M Bohm, M Elce, J S Erdmann, E Lohse, M J In Vitro Research Support, Non-U.S. Gov't United states Circulation Circulation. 1993 Feb;872:454-63..
2 years and 5 months ago
by pharmawuerz
2
*Cyclic AMP-Dependent Adult Aged Base Binding, Calcium/pharmacology Cardiac Cardiomyopathy, Chain Competitive Contraction/drug Coronary Data Dilated/metabolism Disease/metabolism Electric Female Forskolin/pharmacology Humans Isoproterenol/pharmacology Kinases Kinases/genetics/*metabolism Low/*metabolism/physiopathology Male Messenger/metabolism Middle Molecular Muscles/drug Myocardial Oligonucleotide Output, Papillary Polymerase Probes/genetics Protein RNA, Reaction Receptor Sequence Stimulation beta-Adrenergic beta/genetics/metabolism effects Adrenergic
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Binding of purified recombinant beta-arrestin to guanine-nucleotide-binding-protein-coupled receptors
P. Sohlemann, M. Hekman, M. Puzicha, C. Buchen, and M. J. Lohse. Eur J Biochem 232(2):464-72 (September 1995)Sohlemann, P Hekman, M Puzicha, M Buchen, C Lohse, M J Research Support, Non-U.S. Gov't Germany European journal of biochemistry / FEBS Eur J Biochem. 1995 Sep 1;2322:464-72..
P. Sohlemann, M. Hekman, M. Puzicha, C. Buchen, and M. J. Lohse. Eur J Biochem 232(2):464-72 (September 1995)Sohlemann, P Hekman, M Puzicha, M Buchen, C Lohse, M J Research Support, Non-U.S. Gov't Germany European journal of biochemistry / FEBS Eur J Biochem. 1995 Sep 1;2322:464-72..
2 years and 5 months ago
by pharmawuerz
1
*Arrestins AMP-Dependent Adenylate Animals Antigens/genetics/*metabolism Binding Cell Cyclase/metabolism Cyclic Expression Eye GTP-Binding Gene Humans Kinases Kinases/metabolism Kinetics Line Outer Phosphorylation Protein Proteins/genetics/*metabolism Proteins/genetics/metabolism Receptor Recombinant Rhodopsin/metabolism Rod Segment/metabolism Spodoptera beta-2/chemistry/genetics/*metabolism beta-Adrenergic Proteins/metabolism Adrenergic
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Purification and functional characterization of beta-adrenergic receptor kinase expressed in insect cells
P. Sohlemann, M. Hekman, C. Buchen, J. S. Elce, and M. J. Lohse. FEBS Lett 324(1):59-62 (June 1993)Sohlemann, P Hekman, M Buchen, C Elce, J S Lohse, M J Comparative Study Research Support, Non-U.S. Gov't Netherlands FEBS letters FEBS Lett. 1993 Jun 7;3241:59-62..
P. Sohlemann, M. Hekman, C. Buchen, J. S. Elce, and M. J. Lohse. FEBS Lett 324(1):59-62 (June 1993)Sohlemann, P Hekman, M Buchen, C Elce, J S Lohse, M J Comparative Study Research Support, Non-U.S. Gov't Netherlands FEBS letters FEBS Lett. 1993 Jun 7;3241:59-62..
2 years and 5 months ago
by pharmawuerz
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& *Cyclic AMP-Dependent Adenosine Animals Cell Chromatography, Cloning, Exchange Gel Humans Ion Kinases Kinases/genetics/*isolation Kinetics Line Molecular Moths Outer Phosphorylation Protein Proteins/isolation Receptor Recombinant Rhodopsin/metabolism Rod Segment/metabolism Transfection Triphosphate/metabolism beta-Adrenergic purification/*metabolism purification/metabolism
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Phosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2
A. Ruiz-Gomez, J. Humrich, C. Murga, U. Quitterer, M. J. Lohse, and Jr. Mayor. J Biol Chem 275(38):29724-30 (September 2000)Ruiz-Gomez, A Humrich, J Murga, C Quitterer, U Lohse, M J Mayor, F Jr Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 2000 Sep 22;27538:29724-30..
A. Ruiz-Gomez, J. Humrich, C. Murga, U. Quitterer, M. J. Lohse, and Jr. Mayor. J Biol Chem 275(38):29724-30 (September 2000)Ruiz-Gomez, A Humrich, J Murga, C Quitterer, U Lohse, M J Mayor, F Jr Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 2000 Sep 22;27538:29724-30..
2 years and 5 months ago
by pharmawuerz
1
*Signal 2 AMP-Dependent Animals Carrier Cell Cyclic Eye G-Protein-Coupled GTP-Binding Kinase Kinases Kinases/*metabolism Line Nerve Phosphoproteins/*metabolism Phosphorylation Protein Proteins Receptor Regulators Specificity Substrate Tissue Transduction beta-Adrenergic Proteins/metabolism
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Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase
N. S. Roth, P. T. Campbell, M. G. Caron, R. J. Lefkowitz, and M. J. Lohse. Proc Natl Acad Sci U S A 88(14):6201-4 (July 1991)Roth, N S Campbell, P T Caron, M G Lefkowitz, R J Lohse, M J HL16037/HL/NHLBI NIH HHS/United States Comparative Study Research Support, U.S. Gov't, P.H.S. United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1991 Jul 15;8814:6201-4..
N. S. Roth, P. T. Campbell, M. G. Caron, R. J. Lefkowitz, and M. J. Lohse. Proc Natl Acad Sci U S A 88(14):6201-4 (July 1991)Roth, N S Campbell, P T Caron, M G Lefkowitz, R J Lohse, M J HL16037/HL/NHLBI NIH HHS/United States Comparative Study Research Support, U.S. Gov't, P.H.S. United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1991 Jul 15;8814:6201-4..
2 years and 5 months ago
by pharmawuerz
1
*Cyclic A/pharmacology AMP-Dependent Carcinoma, Cell Concanavalin GTP-Binding Humans Isoproterenol/*pharmacology Kinases Kinases/*metabolism Kinetics Line Membrane Permeability Protein Proteins/metabolism Receptor Squamous beta-Adrenergic beta/drug effects/*metabolism Adrenergic
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Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms
J. Pitcher, M. J. Lohse, J. Codina, M. G. Caron, and R. J. Lefkowitz. Biochemistry 31(12):3193-7 (March 1992)Pitcher, J Lohse, M J Codina, J Caron, M G Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, U.S. Gov't, P.H.S. United states Biochemistry Biochemistry. 1992 Mar 31;3112:3193-7..
J. Pitcher, M. J. Lohse, J. Codina, M. G. Caron, and R. J. Lefkowitz. Biochemistry 31(12):3193-7 (March 1992)Pitcher, J Lohse, M J Codina, J Caron, M G Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, U.S. Gov't, P.H.S. United states Biochemistry Biochemistry. 1992 Mar 31;3112:3193-7..
2 years and 5 months ago
by pharmawuerz
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& *Cyclic AMP-Dependent AMP/physiology Adrenergic Animals Antigens/physiology Arrestin C/*pharmacology Cricetinae Cyclic Drug Eye Humans Kinase Kinases Kinases/*pharmacology Lung/chemistry Phosphorylation Protein Proteins/physiology Receptor Retina/chemistry Synergism beta-Adrenergic beta-Agonists/*pharmacology beta/*drug effects/isolation purification
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Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization
S. Pippig, S. Andexinger, and M. J. Lohse. Mol Pharmacol 47(4):666-76 (April 1995)Pippig, S Andexinger, S Lohse, M J Research Support, Non-U.S. Gov't United states Molecular pharmacology Mol Pharmacol. 1995 Apr;474:666-76..
S. Pippig, S. Andexinger, and M. J. Lohse. Mol Pharmacol 47(4):666-76 (April 1995)Pippig, S Andexinger, S Lohse, M J Research Support, Non-U.S. Gov't United states Molecular pharmacology Mol Pharmacol. 1995 Apr;474:666-76..
2 years and 5 months ago
by pharmawuerz
2
AMP-Dependent Cultured Cyclic Humans Kinases Kinases/physiology Monensin/pharmacology Oxazoles/pharmacology Phosphorylation Protein Receptor Sucrose/pharmacology Tumor beta-2/*metabolism beta-Adrenergic Cell Adrenergic
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Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors
S. Pippig, S. Andexinger, K. Daniel, M. Puzicha, M. G. Caron, R. J. Lefkowitz, and M. J. Lohse. J Biol Chem 268(5):3201-8 (February 1993)Pippig, S Andexinger, S Daniel, K Puzicha, M Caron, M G Lefkowitz, R J Lohse, M J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1993 Feb 15;2685:3201-8..
S. Pippig, S. Andexinger, K. Daniel, M. Puzicha, M. G. Caron, R. J. Lefkowitz, and M. J. Lohse. J Biol Chem 268(5):3201-8 (February 1993)Pippig, S Andexinger, S Daniel, K Puzicha, M Caron, M G Lefkowitz, R J Lohse, M J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1993 Feb 15;2685:3201-8..
2 years and 5 months ago
by pharmawuerz
2
& *Arrestins *Cyclic 5'-O-(3-Thiotriphosphate)/pharmacology AMP-Dependent Acid Adenylate Amino Animals Antibodies Antigens/genetics/*metabolism Blotting, CHO Cell Chloride/pharmacology Cricetinae Cyclase/metabolism Data Eye GTP Guanosine Iodine Iodocyanopindolol Isoproterenol/*pharmacology Kinases Kinases/genetics/*metabolism Kinetics Line Magnesium Molecular Peptides/chemical Phosphohydrolases/metabolism Phosphorus Pindolol/analogs Protein Proteins/genetics/*metabolism Radioisotopes Radioisotopes/metabolism Receptor Sequence Transfection Western beta-Adrenergic beta/*drug derivatives/metabolism effects/metabolism synthesis/immunology Adrenergic
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Selectivity of beta-adrenergic receptor kinase 2 for G protein betagamma subunits
S. Muller, A. Straub, and M. J. Lohse. FEBS Lett 401(1):25-9 (January 1997)Muller, S Straub, A Lohse, M J Research Support, Non-U.S. Gov't Netherlands FEBS letters FEBS Lett. 1997 Jan 13;4011:25-9..
S. Muller, A. Straub, and M. J. Lohse. FEBS Lett 401(1):25-9 (January 1997)Muller, S Straub, A Lohse, M J Research Support, Non-U.S. Gov't Netherlands FEBS letters FEBS Lett. 1997 Jan 13;4011:25-9..
2 years and 5 months ago
by pharmawuerz
2
AMP-Dependent Animals Cyclic GTP-Binding Isoenzymes/*metabolism Kinases Kinases/*metabolism Phosphorylation Protein Proteins/metabolism Receptor Recombinant Rhodopsin/metabolism Specificity Substrate beta-Adrenergic
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Specific enhancement of beta-adrenergic receptor kinase activity by defined G-protein beta and gamma subunits
S. Muller, M. Hekman, and M. J. Lohse. Proc Natl Acad Sci U S A 90(22):10439-43 (November 1993)Muller, S Hekman, M Lohse, M J In Vitro Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1993 Nov 15;9022:10439-43..
S. Muller, M. Hekman, and M. J. Lohse. Proc Natl Acad Sci U S A 90(22):10439-43 (November 1993)Muller, S Hekman, M Lohse, M J In Vitro Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1993 Nov 15;9022:10439-43..
2 years and 5 months ago
by pharmawuerz
2
AMP-Dependent Activation Animals Baculoviridae Bordetella/pharmacology Cyclic Enzyme Factors, GTP-Binding Kinases Kinases/*metabolism Moths Phosphoproteins/metabolism Protein Proteins/metabolism Receptor Recombinant Rhodopsin/metabolism Virulence beta-Adrenergic beta/*metabolism Adrenergic
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Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2
K. Lorenz, M. J. Lohse, and U. Quitterer. Nature 426(6966):574-9 (December 2003)Lorenz, Kristina Lohse, Martin J Quitterer, Ursula Research Support, Non-U.S. Gov't England Nature Nature. 2003 Dec 4;4266966:574-9..
K. Lorenz, M. J. Lohse, and U. Quitterer. Nature 426(6966):574-9 (December 2003)Lorenz, Kristina Lohse, Martin J Quitterer, Ursula Research Support, Non-U.S. Gov't England Nature Nature. 2003 Dec 4;4266966:574-9..
2 years and 5 months ago
by pharmawuerz
2
& *Androgen-Binding 2 3 AMP-Dependent Animals Binding Brain/metabolism C/*metabolism Cardiac/metabolism Carrier Cell Cyclic Enzyme G-Protein-Coupled Humans Inhibitors/*metabolism Interference Kinase Kinases Kinases/*antagonists Line Mice Myocytes, Phosphatidylethanolamine Phospholipid Phosphorylation Precipitin Protein Proteins Proteins/genetics/*metabolism Proto-Oncogene RNA Rats Receptor Signal Specificity Substrate Tests Transduction Transfer Uteroglobin beta-Adrenergic c-raf/*antagonists inhibitors/genetics/metabolism
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What is the role of beta-adrenergic signaling in heart failure?
M. J. Lohse, S. Engelhardt, and T. Eschenhagen. Circ Res 93(10):896-906 (November 2003)Lohse, Martin J Engelhardt, Stefan Eschenhagen, Thomas Review United States Circulation research Circ Res. 2003 Nov 14;9310:896-906..
M. J. Lohse, S. Engelhardt, and T. Eschenhagen. Circ Res 93(10):896-906 (November 2003)Lohse, Martin J Engelhardt, Stefan Eschenhagen, Thomas Review United States Circulation research Circ Res. 2003 Nov 14;9310:896-906..
2 years and 5 months ago
by pharmawuerz
2
*Signal AMP-Dependent Adrenergic Animal Animals Cyclic Disease Failure/drug GTP-Binding Heart Humans Kinases Kinases/metabolism Mice Models, Myocardium/*metabolism Protein Proteins/metabolism Receptor Transduction Transgenic beta-Adrenergic beta-Antagonists/therapeutic beta/genetics/*metabolism therapy/*physiopathology use
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beta-Arrestin: a protein that regulates beta-adrenergic receptor function
M. J. Lohse, J. L. Benovic, J. Codina, M. G. Caron, and R. J. Lefkowitz. Science 248(4962):1547-50 (June 1990)Lohse, M J Benovic, J L Codina, J Caron, M G Lefkowitz, R J DK19318/DK/NIDDK NIH HHS/United States HL16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states Science New York, N.Y. Science. 1990 Jun 22;2484962:1547-50..
M. J. Lohse, J. L. Benovic, J. Codina, M. G. Caron, and R. J. Lefkowitz. Science 248(4962):1547-50 (June 1990)Lohse, M J Benovic, J L Codina, J Caron, M G Lefkowitz, R J DK19318/DK/NIDDK NIH HHS/United States HL16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states Science New York, N.Y. Science. 1990 Jun 22;2484962:1547-50..
2 years and 5 months ago
by pharmawuerz
2
& *Cyclic AMP-Dependent Acid Amino Animals Antigens/*genetics/isolation Arrestin Blotting, Chromatography, Cloning, DNA/genetics Data Exchange Expression Eye Gene Inhibitors/*pharmacology Ion Kinases Kinases/*pharmacology Messenger/analysis Molecular Northern Phosphodiesterase Phosphorylation Protein Proteins/*genetics/isolation RNA, Receptor Regulation Sequence Transfection beta-Adrenergic beta/*drug effects/physiology purification/pharmacology Adrenergic
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Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems
M. J. Lohse, S. Andexinger, J. Pitcher, S. Trukawinski, J. Codina, J. P. Faure, M. G. Caron, and R. J. Lefkowitz. J Biol Chem 267(12):8558-64 (April 1992)Lohse, M J Andexinger, S Pitcher, J Trukawinski, S Codina, J Faure, J P Caron, M G Lefkowitz, R J DK 19318/DK/NIDDK NIH HHS/United States HL 16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 1992 Apr 25;26712:8558-64..
M. J. Lohse, S. Andexinger, J. Pitcher, S. Trukawinski, J. Codina, J. P. Faure, M. G. Caron, and R. J. Lefkowitz. J Biol Chem 267(12):8558-64 (April 1992)Lohse, M J Andexinger, S Pitcher, J Trukawinski, S Codina, J Faure, J P Caron, M G Lefkowitz, R J DK 19318/DK/NIDDK NIH HHS/United States HL 16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 1992 Apr 25;26712:8558-64..
2 years and 5 months ago
by pharmawuerz
2
& *Arrestins *Cyclic 1 AMP-Dependent Activation Adrenergic Animals Antigens/isolation Arrestin Blotting, Cell Chromatography, Cricetinae DNA/genetics Electrophoresis, Enzyme Eye G-Protein-Coupled GTP GTP-Binding Gel Kinase Kinases Kinases/*metabolism Line Liquid Membrane Phosphohydrolases/metabolism Phosphorylation Polyacrylamide Protein Proteins/isolation Proteins/metabolism Receptor Rhodopsin/*metabolism Specificity Substrate Western beta-Adrenergic beta-Antagonists/metabolism beta/*metabolism purification/*metabolism
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Effects of two Gbetagamma-binding proteins--N-terminally truncated phosducin and beta-adrenergic receptor kinase C terminus betaARKct--in heart failure
Z. Li, K. L. Laugwitz, K. Pinkernell, I. Pragst, C. Baumgartner, E. Hoffmann, K. Rosport, G. Munch, A. Moretti, J. Humrich, M. J. Lohse, and M. Ungerer. Gene Ther 10(16):1354-61 (August 2003)Li, Z Laugwitz, K-L Pinkernell, K Pragst, I Baumgartner, C Hoffmann, E Rosport, K Munch, G Moretti, A Humrich, J Lohse, M J Ungerer, M England Gene therapy Gene Ther. 2003 Aug;1016:1354-61..
Z. Li, K. L. Laugwitz, K. Pinkernell, I. Pragst, C. Baumgartner, E. Hoffmann, K. Rosport, G. Munch, A. Moretti, J. Humrich, M. J. Lohse, and M. Ungerer. Gene Ther 10(16):1354-61 (August 2003)Li, Z Laugwitz, K-L Pinkernell, K Pragst, I Baumgartner, C Hoffmann, E Rosport, K Munch, G Moretti, A Humrich, J Lohse, M J Ungerer, M England Gene therapy Gene Ther. 2003 Aug;1016:1354-61..
2 years and 5 months ago
by pharmawuerz
2
& AMP-Dependent AMP/metabolism Adenoviridae/genetics Animal Animals Artificial C Cardiac Cardiac/metabolism Contraction Cyclic Eye Failure/*therapy GTP-Binding Gene Genetic Heart Heterotrimeric Humans Kinases Kinases/*genetics Models, Myocardial Myocardium/*metabolism Myocytes, Pacing, Phospholipases/metabolism Phosphoproteins/*genetics Protein Proteins/*genetics Proteins/metabolism Rabbits Receptor Regulators Therapy/*methods Type Vectors/administration beta-Adrenergic dosage
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Kinetics of G-protein-coupled receptor signalling and desensitization
C. Krasel, J. P. Vilardaga, M. Bunemann, and M. J. Lohse. Biochem Soc Trans 32(Pt 6):1029-31 (December 2004)Krasel, C Vilardaga, J-P Bunemann, M Lohse, M J Research Support, Non-U.S. Gov't England Biochemical Society transactions Biochem Soc Trans. 2004 Dec;32Pt 6:1029-31..
C. Krasel, J. P. Vilardaga, M. Bunemann, and M. J. Lohse. Biochem Soc Trans 32(Pt 6):1029-31 (December 2004)Krasel, C Vilardaga, J-P Bunemann, M Lohse, M J Research Support, Non-U.S. Gov't England Biochemical Society transactions Biochem Soc Trans. 2004 Dec;32Pt 6:1029-31..
2 years and 5 months ago
by pharmawuerz
2
AMP-Dependent Animals Cyclic Energy Fluorescence G-Protein-Coupled/*physiology Humans Kinases Kinases/metabolism Kinetics Protein Receptor Resonance Signal Transduction/*physiology Transfer beta-Adrenergic
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Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin
C. Krasel, S. Dammeier, R. Winstel, J. Brockmann, H. Mischak, and M. J. Lohse. J Biol Chem 276(3):1911-5 (January 2001)Krasel, C Dammeier, S Winstel, R Brockmann, J Mischak, H Lohse, M J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2001 Jan 19;2763:1911-5. Epub 2000 Oct 19..
C. Krasel, S. Dammeier, R. Winstel, J. Brockmann, H. Mischak, and M. J. Lohse. J Biol Chem 276(3):1911-5 (January 2001)Krasel, C Dammeier, S Winstel, R Brockmann, J Mischak, H Lohse, M J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2001 Jan 19;2763:1911-5. Epub 2000 Oct 19..
2 years and 5 months ago
by pharmawuerz
2
& 2 AMP-Dependent Animals C/*metabolism Calmodulin/*metabolism Cell Chromatography, Cyclic G-Protein-Coupled High Humans Isoenzymes/*metabolism Kinase Kinases Kinases/antagonists Line Liquid Mass Mutagenesis, Phosphorylation Pressure Protein Receptor Serine/metabolism Site-Directed Specificity Spectrometry Substrate beta-Adrenergic inhibitors/genetics/*metabolism
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