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1Mechanistic Insights into the Anrorc-Like Rearrangement between Methylhydrazine and 1,2,4-Oxadiazole Derivatives
S. Gallardo-Fuentes, and R. Contreras. Organic & Biomolecular Chemistry, 13 (36): 9439-9444 (2015)
6 years ago by @dqcauchile
show all tags
density
aromatic-substitution
nucleophile,
reactivities,
5-perfluoroalkyl-1,2,4-oxadiazoles,
dqcauchile
heterocyclic-compounds,
functionals,
organic-chemistry,
hydrazine,
fluorinated
reactions,
kinetics
indazoles,
densityaromatic-substitutionnucleophile,reactivities,5-perfluoroalkyl-1,2,4-oxadiazoles,dqcauchileheterocyclic-compounds,functionals,organic-chemistry,hydrazine,fluorinatedreactions,kineticsindazoles,
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1Solvent Effect on a Model Snar Reaction in Ionic Liquid/Water Mixtures at Different Compositions
B. Sanchez, C. Calderon, C. Garrido, R. Contreras, and P. Campodonico. New Journal of Chemistry, 42 (12): 9645-9650 (2018)
6 years ago by @dqcauchile
show all tags
catalysis,
molecules,
water,
aromatic
mixed-solvents,
preferential
dqcauchile
nucleophilic-substitution,
liquids,
nitro-group,
binary-mixtures,
solvation,
kinetics
catalysis,molecules,water,aromaticmixed-solvents,preferentialdqcauchilenucleophilic-substitution,liquids,nitro-group,binary-mixtures,solvation,kinetics
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1Dynamic Proteomics of Individual Cancer Cells in Response to a Drug
A. Cohen, N. Geva-Zatorsky, E. Eden, M. Frenkel-Morgenstern, I. Issaeva, A. Sigal, R. Milo, C. Cohen-Saidon, Y. Liron, Z. Kam and 4 other author(s). Science, 322 (5907): 1511--1516 (Dec 5, 2008)
7 years ago by @karthikraman
show all tags
cancer
kinetics
cancerkinetics
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4"Formate assay in body fluids: application in methanol poisoning"
A. Makar, K. McMartin, M. Palese, and T. Tephly. Biochemical medicine, 13 (2): 117–126 (1975)
7 years ago by @marc.eichenberger
show all tags
Body_Fluids/analysis
Carbon_Dioxide/blood
Animals
Hydrogen-Ion_Concentration
Pseudomonas/enzymology
Humans
Formates/blood/poisoning
Kinetics
Haplorhini
Aldehyde_Oxidoreductases/metabolism
Methanol/blood
Methods
Body_Fluids/analysisCarbon_Dioxide/bloodAnimalsHydrogen-Ion_ConcentrationPseudomonas/enzymologyHumansFormates/blood/poisoningKineticsHaplorhiniAldehyde_Oxidoreductases/metabolismMethanol/bloodMethods
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1Enhanced Modeling via Network Theory: Adaptive Sampling of Markov State Models
G. Bowman, D. Ensign, and V. Pande. Journal of Chemical Theory and Computation, 6 (3): 787-794 (2010)
8 years ago by @salotz
show all tags
markov-state-models
stochastic-processes
kinetics
markov-state-modelsstochastic-processeskinetics
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1Kinetic Analysis of the Reaction between (V2O5)n=1,2+ and Ethylene.
N. Moore, R. Mitric, D. Justes, V. Bonacic-Koutecky, and A. Castleman Jr.. Journal of Physical Chemistry B, 110 (7): 3015--3022 (2006)
8 years ago by @jhoche
show all tags
cluster
ethylene
cation
vanadia
mechanism
kinetics
clusterethylenecationvanadiamechanismkinetics
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1Load-Relief of Walking Aids on Osseointegrated Fixation: Instrument for Evidence-Based Practice
L. Frossard, K. Hagberg, E. Haggstrom, and R. Branemark. Neural Systems and Rehabilitation Engineering, IEEE Transactions on, 17 (1): 9 -14 (February 2009)
14 years ago by @bunke
show all tags
evidence-basedpractice
Evidence-BasedMedicine
ProsthesisDesign
DataInterpretation
Leg
Crutches
load-relief
transducers
Walking
Biomechanics
walkingaids
portablekineticsystem
EquipmentDesign
Kinetics
Statistical
Models
osseointegratedfixation
activetransfemoralamputee
Canes
Humans
ArtificialLimbs
Male
handicappedaids
elbowcrutches
gaitanalysis
orthotics
Amputation
Adult
six-channeltransducer
lowerlimbamputeelocomotion
evidence-basedpracticeEvidence-BasedMedicineProsthesisDesignDataInterpretationLegCrutchesload-relieftransducersWalkingBiomechanicswalkingaidsportablekineticsystemEquipmentDesignKineticsStatisticalModelsosseointegratedfixationactivetransfemoralamputeeCanesHumansArtificialLimbsMalehandicappedaidselbowcrutchesgaitanalysisorthoticsAmputationAdultsix-channeltransducerlowerlimbamputeelocomotion
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1Xenotransplantation of porcine and bovine islets without immunosuppression using uncoated alginate microspheres.
R. Lanza, W. Kuhtreiber, D. Ecker, J. Staruk, and W. Chick. Transplantation, 59 (10): 1377-84 (1995)
14 years ago by @pawelsikorski
show all tags
Transplantation,
Mice,
G/metabolism
&
C57BL
Support,
Non-P.H.S.
Animals
Hexuronic
Acids
Kinetics
Glucuronic
Mice
;
Diabetes
Thyroglobulin/metabolism
Inbred
Cavity/pathology
Experimental/immunology/metabolism
dosage
Peritoneal
Transplantation/*immunology/pathology
Acid
Male
Gov't,
Research
Immunoglobulin
Alginates/*administration
Microspheres
Swine
U.S.
Cattle
Insulin/metabolism
Heterologous/*immunology
of
Langerhans
Glucose/metabolism
Islets
Mellitus,
Transplantation,Mice,G/metabolism&C57BLSupport,Non-P.H.S.AnimalsHexuronicAcidsKineticsGlucuronicMice;DiabetesThyroglobulin/metabolismInbredCavity/pathologyExperimental/immunology/metabolismdosagePeritonealTransplantation/*immunology/pathologyAcidMaleGov't,ResearchImmunoglobulinAlginates/*administrationMicrospheresSwineU.S.CattleInsulin/metabolismHeterologous/*immunologyofLangerhansGlucose/metabolismIsletsMellitus,
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1Guanine nucleotide effects on 8-cyclopentyl-1,3-3Hdipropylxanthine binding to membrane-bound and solubilized A1 adenosine receptors of rat brain
K. Klotz, R. Keil, F. Zimmer, and U. Schwabe. J Neurochem, 54 (6): 1988-94 (June 1990)Klotz, K N Keil, R Zimmer, F J Schwabe, U Research Support, Non-U.S. Gov't United states Journal of neurochemistry J Neurochem. 1990 Jun;54(6):1988-94..
15 years ago by @pharmawuerz
show all tags
Factors
Centrifugation
Solubility
Brain/*metabolism
Guanosine
Xanthines/*metabolism
Membranes/metabolism
Purinergic/*metabolism
Rats
Time
Animals
Receptor
Ethylmaleimide/pharmacology
Kinetics
Triphosphate/*pharmacology
FactorsCentrifugationSolubilityBrain/*metabolismGuanosineXanthines/*metabolismMembranes/metabolismPurinergic/*metabolismRatsTimeAnimalsReceptorEthylmaleimide/pharmacologyKineticsTriphosphate/*pharmacology
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1Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors
M. Lohse, R. Lefkowitz, M. Caron, and J. Benovic. Proc Natl Acad Sci U S A, 86 (9): 3011-5 (May 1989)Lohse, M J Lefkowitz, R J Caron, M G Benovic, J L Comparative Study Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1989 May;86(9):3011-5..
15 years ago by @pharmawuerz
show all tags
Lung/analysis
Isoproterenol/pharmacology
Cricetinae
Phosphorylation
Humans
*Protein
Heparin/pharmacology
Tolerance
Permeability
Adrenergic
Animals
Inhibitors
Receptor
Kinase
Membrane
Tumor
Kinetics
beta/drug
Cultured
effects/*metabolism
Cell
Digitonin
Drug
Lung/analysisIsoproterenol/pharmacologyCricetinaePhosphorylationHumans*ProteinHeparin/pharmacologyTolerancePermeabilityAdrenergicAnimalsInhibitorsReceptorKinaseMembraneTumorKineticsbeta/drugCulturedeffects/*metabolismCellDigitoninDrug
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1Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase
J. Benovic, J. Onorato, M. Lohse, H. Dohlman, C. Staniszewski, M. Caron, and R. Lefkowitz. Br J Clin Pharmacol, (1990)Benovic, J L Onorato, J Lohse, M J Dohlman, H G Staniszewski, C Caron, M G Lefkowitz, R J England British journal of clinical pharmacology Br J Clin Pharmacol. 1990;30 Suppl 1:3S-12S..
15 years ago by @pharmawuerz
show all tags
synthesis/*metabolism/pharmacology
Cricetinae
Electrophoresis,
beta/*chemistry/metabolism
Data
Sequence
Gel
Peptides/chemical
Protein
beta-Adrenergic
Substrate
Animals
Inhibitors
Receptor
Cyclic
Kinase
Kinases/isolation
purification/*metabolism
Kinetics
Acid
Phosphorylation
Polyacrylamide
Adrenergic
Proteins/metabolism
Kinases
Molecular
Specificity
GTP-Binding
Amino
AMP-Dependent
synthesis/*metabolism/pharmacologyCricetinaeElectrophoresis,beta/*chemistry/metabolismDataSequenceGelPeptides/chemicalProteinbeta-AdrenergicSubstrateAnimalsInhibitorsReceptorCyclicKinaseKinases/isolationpurification/*metabolismKineticsAcidPhosphorylationPolyacrylamideAdrenergicProteins/metabolismKinasesMolecularSpecificityGTP-BindingAminoAMP-Dependent
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13HHEMADO--a novel tritiated agonist selective for the human adenosine A3 receptor
K. Klotz, N. Falgner, S. Kachler, C. Lambertucci, S. Vittori, R. Volpini, and G. Cristalli. Eur J Pharmacol, 556 (1-3): 14-8 (February 2007)Klotz, Karl-Norbert Falgner, Nico Kachler, Sonja Lambertucci, Catia Vittori, Sauro Volpini, Rosaria Cristalli, Gloria Research Support, Non-U.S. Gov't Netherlands European journal of pharmacology Eur J Pharmacol. 2007 Feb 5;556(1-3):14-8. Epub 2006 Oct 27..
15 years ago by @pharmawuerz
show all tags
Adenosine/*analogs
Cricetinae
Cricetulus
&
Humans
Radioligand
Tritium
CHO
derivatives/pharmacology
A3/*agonists/metabolism
Assay
Animals
Receptor
Sensitivity
Specificity
and
Kinetics
Ligands
Adenosine
Cell
Adenosine/*analogsCricetinaeCricetulus&HumansRadioligandTritiumCHOderivatives/pharmacologyA3/*agonists/metabolismAssayAnimalsReceptorSensitivitySpecificityandKineticsLigandsAdenosineCell
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1Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors
S. Pippig, S. Andexinger, K. Daniel, M. Puzicha, M. Caron, R. Lefkowitz, and M. Lohse. J Biol Chem, 268 (5): 3201-8 (February 1993)Pippig, S Andexinger, S Daniel, K Puzicha, M Caron, M G Lefkowitz, R J Lohse, M J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1993 Feb 15;268(5):3201-8..
15 years ago by @pharmawuerz
show all tags
*Arrestins
Cricetinae
synthesis/immunology
Isoproterenol/*pharmacology
&
5'-O-(3-Thiotriphosphate)/pharmacology
Pindolol/analogs
Phosphorus
Data
Sequence
Radioisotopes/metabolism
Peptides/chemical
Protein
beta-Adrenergic
*Cyclic
Animals
Proteins/genetics/*metabolism
Receptor
Blotting,
Line
Kinetics
effects/metabolism
Chloride/pharmacology
Cyclase/metabolism
beta/*drug
Acid
GTP
Guanosine
CHO
Adenylate
Radioisotopes
Antibodies
Phosphohydrolases/metabolism
Kinases/genetics/*metabolism
Transfection
Adrenergic
derivatives/metabolism
Eye
Kinases
Molecular
Western
Iodocyanopindolol
Antigens/genetics/*metabolism
Magnesium
Amino
Iodine
AMP-Dependent
Cell
*ArrestinsCricetinaesynthesis/immunologyIsoproterenol/*pharmacology&5'-O-(3-Thiotriphosphate)/pharmacologyPindolol/analogsPhosphorusDataSequenceRadioisotopes/metabolismPeptides/chemicalProteinbeta-Adrenergic*CyclicAnimalsProteins/genetics/*metabolismReceptorBlotting,LineKineticseffects/metabolismChloride/pharmacologyCyclase/metabolismbeta/*drugAcidGTPGuanosineCHOAdenylateRadioisotopesAntibodiesPhosphohydrolases/metabolismKinases/genetics/*metabolismTransfectionAdrenergicderivatives/metabolismEyeKinasesMolecularWesternIodocyanopindololAntigens/genetics/*metabolismMagnesiumAminoIodineAMP-DependentCell
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1Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association
J. Vilardaga, C. Krasel, S. Chauvin, T. Bambino, M. Lohse, and R. Nissenson. J Biol Chem, 277 (10): 8121-9 (March 2002)Vilardaga, Jean-Pierre Krasel, Cornelius Chauvin, Stephanie Bambino, Tom Lohse, Martin J Nissenson, Robert A DK 35323/DK/NIDDK NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. United States The Journal of biological chemistry J Biol Chem. 2002 Mar 8;277(10):8121-9. Epub 2001 Nov 28..
15 years ago by @pharmawuerz
show all tags
Luminescent
Binding
Structure,
Tertiary
Cytoplasm/metabolism
Asparagine/chemistry
Membrane/metabolism
Protein
Receptor
Blotting,
Cyclic
DNA,
Line
Kinetics
Microscopy,
Transduction
Arrestins/*chemistry/*metabolism
Ligands
Mutation
Lysine/chemistry
Transport
AMP/metabolism
Green
Factors
Phosphorylation
Humans
Immunoblotting
Confocal
Time
Proteins/metabolism
Proteins
Western
Fluorescent
Parathyroid
Complementary/metabolism
Endocytosis
Signal
Hormone/*chemistry/*metabolism
Cell
LuminescentBindingStructure,TertiaryCytoplasm/metabolismAsparagine/chemistryMembrane/metabolismProteinReceptorBlotting,CyclicDNA,LineKineticsMicroscopy,TransductionArrestins/*chemistry/*metabolismLigandsMutationLysine/chemistryTransportAMP/metabolismGreenFactorsPhosphorylationHumansImmunoblottingConfocalTimeProteins/metabolismProteinsWesternFluorescentParathyroidComplementary/metabolismEndocytosisSignalHormone/*chemistry/*metabolismCell
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1C-terminal fragments of the alpha 1C (CaV1.2) subunit associate with and regulate L-type calcium channels containing C-terminal-truncated alpha 1C subunits
T. Gao, A. Cuadra, H. Ma, M. Bunemann, B. Gerhardstein, T. Cheng, R. Eick, and M. Hosey. J Biol Chem, 276 (24): 21089-97 (June 2001)Gao, T Cuadra, A E Ma, H Bunemann, M Gerhardstein, B L Cheng, T Eick, R T Hosey, M M HL23306/HL/NHLBI NIH HHS/United States T32-DK07169/DK/NIDDK NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States The Journal of biological chemistry J Biol Chem. 2001 Jun 15;276(24):21089-97. Epub 2001 Mar 26..
15 years ago by @pharmawuerz
show all tags
Patch-Clamp
Barium/pharmacology
Techniques
Channels,
Sequence
Mammals
Fragments/chemistry/pharmacology
Protein
Animals
Line
Kinetics
effects/metabolism
L-Type/*chemistry/drug
effects/*physiology
Potentials/drug
Calcium
Humans
effects/physiology
Transfection
Membrane/physiology
Subunits
Membrane
Proteins/chemistry/drug
Deletion
Peptide
Recombinant
Cell
Patch-ClampBarium/pharmacologyTechniquesChannels,SequenceMammalsFragments/chemistry/pharmacologyProteinAnimalsLineKineticseffects/metabolismL-Type/*chemistry/drugeffects/*physiologyPotentials/drugCalciumHumanseffects/physiologyTransfectionMembrane/physiologySubunitsMembraneProteins/chemistry/drugDeletionPeptideRecombinantCell
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1Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases
J. Leroy, A. Abi-Gerges, V. Nikolaev, W. Richter, P. Lechene, J. Mazet, M. Conti, R. Fischmeister, and G. Vandecasteele. Circ Res, 102 (9): 1091-100 (May 2008)Leroy, Jerome Abi-Gerges, Aniella Nikolaev, Viacheslav O Richter, Wito Lechene, Patrick Mazet, Jean-Luc Conti, Marco Fischmeister, Rodolphe Vandecasteele, Gregoire HD20788/HD/NICHD NIH HHS/United States Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States Circulation research Circ Res. 2008 May 9;102(9):1091-100. Epub 2008 Mar 27..
15 years ago by @pharmawuerz
show all tags
Techniques
Fluorescence/methods
Nucleotide
Rats
Biosensing
Wistar
Exchange
effects
*Myocardial
Potentials
AMP/*metabolism
Inhibitors/pharmacology
Kinetics
Transfer
Resonance
effects/*metabolism
Calcium
Activation
Phosphodiesterases,
Sarcolemma/metabolism
Dose-Response
L-Type/*metabolism
Membrane
Cultured
Relationship,
Energy
Cell
Phosphodiesterase
&
inhibitors/*metabolism
Contraction/drug
4/antagonists
Channels,
Transduction/drug
Ventricles/metabolism
Kinases/metabolism
Protein
Cation
Type
Cardiac/drug
Animals
Receptor
Nucleotide-Gated
Cyclic
3/antagonists
Quinolones/pharmacology
Microscopy,
beta/drug
beta-Agonists/pharmacology
Cytosol/metabolism
Isoproterenol/pharmacology
Factors/genetics/metabolism
Heart
Phosphorylation
Myocytes,
effects/enzymology/*metabolism
Male
Fluorescence
Transfection
Adrenergic
Guanine
*Signal
Channels/genetics/metabolism
Enzyme
AMP-Dependent
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone/pharmacology
Drug
TechniquesFluorescence/methodsNucleotideRatsBiosensingWistarExchangeeffects*MyocardialPotentialsAMP/*metabolismInhibitors/pharmacologyKineticsTransferResonanceeffects/*metabolismCalciumActivationPhosphodiesterases,Sarcolemma/metabolismDose-ResponseL-Type/*metabolismMembraneCulturedRelationship,EnergyCellPhosphodiesterase&inhibitors/*metabolismContraction/drug4/antagonistsChannels,Transduction/drugVentricles/metabolismKinases/metabolismProteinCationTypeCardiac/drugAnimalsReceptorNucleotide-GatedCyclic3/antagonistsQuinolones/pharmacologyMicroscopy,beta/drugbeta-Agonists/pharmacologyCytosol/metabolismIsoproterenol/pharmacologyFactors/genetics/metabolismHeartPhosphorylationMyocytes,effects/enzymology/*metabolismMaleFluorescenceTransfectionAdrenergicGuanine*SignalChannels/genetics/metabolismEnzymeAMP-Dependent4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone/pharmacologyDrug
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1Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium
B. Palmer, D. Fishbaugher, J. Schmitt, Y. Wang, N. Alpert, C. Seidman, J. Seidman, P. VanBuren, and D. Maughan. Am J Physiol Heart Circ Physiol, 287 (1): H91-9 (July 2004)Palmer, Bradley M Fishbaugher, David E Schmitt, Joachim P Wang, Yuan Alpert, Norman R Seidman, Christine E Seidman, J G VanBuren, Peter Maughan, David W HL-59408-3/HL/NHLBI NIH HHS/United States In Vitro Research Support, U.S. Gov't, P.H.S. United States American journal of physiology. Heart and circulatory physiology Am J Physiol Heart Circ Physiol. 2004 Jul;287(1):H91-9. Epub 2004 Mar 4..
15 years ago by @pharmawuerz
show all tags
*Mutation,
Hypertrophic/*genetics/metabolism/physiopathology
Cysteine/genetics
*Myocardial
Animals
Myocardium/metabolism
Kinetics
Chains/*genetics/metabolism
Mice
Mutation
Missense
Myosins/*genetics/metabolism
Adenosine
Triphosphatases/metabolism
Heavy
Factors
*Point
Actins/metabolism
Ventricular
Glutamine/genetics
Male
Activation
Time
Contraction
Cardiomyopathy,
Isometric
Arginine/genetics
*Heterozygote
Myosin
Calcium/metabolism
Enzyme
*Mutation,Hypertrophic/*genetics/metabolism/physiopathologyCysteine/genetics*MyocardialAnimalsMyocardium/metabolismKineticsChains/*genetics/metabolismMiceMutationMissenseMyosins/*genetics/metabolismAdenosineTriphosphatases/metabolismHeavyFactors*PointActins/metabolismVentricularGlutamine/geneticsMaleActivationTimeContractionCardiomyopathy,IsometricArginine/genetics*HeterozygoteMyosinCalcium/metabolismEnzyme
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1Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors
M. Lohse, J. Benovic, M. Caron, and R. Lefkowitz. J Biol Chem, 265 (6): 3202-11 (February 1990)Lohse, M J Benovic, J L Caron, M G Lefkowitz, R J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1990 Feb 25;265(6):3202-11..
15 years ago by @pharmawuerz
show all tags
Isoproterenol/*pharmacology
Proteins/*pharmacology
Permeability
Concanavalin
Heparin/*pharmacology
Inhibitors/*pharmacology
Signaling
Receptor
Magnesium/pharmacology
Line
Carcinoma,
Kinetics
effects/metabolism
Cyclase/metabolism
beta/*drug
Humans
Peptides
Adenylate
*Intracellular
A/pharmacology
Adrenergic
Proteins
Carrier
Peptides/pharmacology
and
Membrane
Enzyme
Squamous
Cell
Isoproterenol/*pharmacologyProteins/*pharmacologyPermeabilityConcanavalinHeparin/*pharmacologyInhibitors/*pharmacologySignalingReceptorMagnesium/pharmacologyLineCarcinoma,Kineticseffects/metabolismCyclase/metabolismbeta/*drugHumansPeptidesAdenylate*IntracellularA/pharmacologyAdrenergicProteinsCarrierPeptides/pharmacologyandMembraneEnzymeSquamousCell
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1Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein
J. Vilardaga, M. Frank, C. Krasel, C. Dees, R. Nissenson, and M. Lohse. J Biol Chem, 276 (36): 33435-43 (September 2001)Vilardaga, J P Frank, M Krasel, C Dees, C Nissenson, R A Lohse, M J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2001 Sep 7;276(36):33435-43. Epub 2001 May 31..
15 years ago by @pharmawuerz
show all tags
COS
Protein-Serine-Threonine
Competitive
Inhibitory
Kinetics
Mutation
Conformation
Factors
Compounds/pharmacology
Hormone/*metabolism
Hormone,
Activation
Immunoblotting
Ions/metabolism
Chlorides/pharmacology
Time
Arrestin/*metabolism
Dose-Response
50
Relationship,
Phosphates/metabolism
Cell
Histidine/chemistry
Binding
Inositol
Sites
Zinc
Concentration
Membrane/metabolism
Protein
1
Type
Animals
Receptor
Cyclic
Kinases/*metabolism
Zinc/metabolism
Transduction
Ligands
AMP/metabolism
Phosphorylation
Binding,
Arrestins/metabolism
Proteins/metabolism
GTP-Binding
Enzyme
Parathyroid
Signal
Drug
COSProtein-Serine-ThreonineCompetitiveInhibitoryKineticsMutationConformationFactorsCompounds/pharmacologyHormone/*metabolismHormone,ActivationImmunoblottingIons/metabolismChlorides/pharmacologyTimeArrestin/*metabolismDose-Response50Relationship,Phosphates/metabolismCellHistidine/chemistryBindingInositolSitesZincConcentrationMembrane/metabolismProtein1TypeAnimalsReceptorCyclicKinases/*metabolismZinc/metabolismTransductionLigandsAMP/metabolismPhosphorylationBinding,Arrestins/metabolismProteins/metabolismGTP-BindingEnzymeParathyroidSignalDrug
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1Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase
N. Roth, P. Campbell, M. Caron, R. Lefkowitz, and M. Lohse. Proc Natl Acad Sci U S A, 88 (14): 6201-4 (July 1991)Roth, N S Campbell, P T Caron, M G Lefkowitz, R J Lohse, M J HL16037/HL/NHLBI NIH HHS/United States Comparative Study Research Support, U.S. Gov't, P.H.S. United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6201-4..
15 years ago by @pharmawuerz
show all tags
Isoproterenol/*pharmacology
Humans
Permeability
A/pharmacology
Adrenergic
Concanavalin
Proteins/metabolism
Protein
beta-Adrenergic
*Cyclic
Receptor
Kinases
Kinases/*metabolism
Line
Carcinoma,
Membrane
Kinetics
GTP-Binding
beta/drug
effects/*metabolism
Squamous
AMP-Dependent
Cell
Isoproterenol/*pharmacologyHumansPermeabilityA/pharmacologyAdrenergicConcanavalinProteins/metabolismProteinbeta-Adrenergic*CyclicReceptorKinasesKinases/*metabolismLineCarcinoma,MembraneKineticsGTP-Bindingbeta/drugeffects/*metabolismSquamousAMP-DependentCell
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