%0 Journal Article %1 Resch2006 %A Resch, Bernhard %A Jammernegg, Andrea %A Perl, Eva %A Riccabona, Michael %A Maurer, Ute %A M?ller, Wilhelm D %D 2006 %J Pediatr Radiol %K Cerebral Palsy; Ventricles; Cohort Studies; Developmental Disabilities; Echoencephalography; Female; Humans; Infant, Newborn; Premature; Premature, Diseases; Leukomalacia, Periventricular; Male; Mental Retardation; Pregnancy; Prognosis; Retrospective Studies %N 8 %P 810--815 %R 10.1007/s00247-006-0178-2 %T Correlation of grading and duration of periventricular echodensities with neurodevelopmental outcome in preterm infants. %U http://dx.doi.org/10.1007/s00247-006-0178-2 %V 36 %X BACKGROUND: Transient periventricular echodensities (PVE) in preterm infants affect neurodevelopmental outcome. OBJECTIVE: To correlate the duration and grading of PVE with neurodevelopmental outcome. MATERIALS AND METHODS: A retrospective, single-centre cohort study of infants with PVE diagnosed by ultrasonography from 1995 to 2000 with blinded grading and recognition of duration of PVE. RESULTS: A total of 72 infants (median gestational age 32 weeks, median birth weight 1,668 g) were diagnosed as having PVE. Minor neurological abnormalities were diagnosed in seven (10\%), cerebral palsy in six (8\%), developmental delay in seven (10\%), and mild mental retardation in two (3\%) of the infants. Differences regarding adverse outcome were not significant between infants with severity grade 1 compared to severity grade 2 (16\% and 22\%, respectively). There was a significant increase in adverse neurodevelopmental outcome with increasing duration of PVE. Of 33 infants with duration of PVE<7 days, 1 (3\%) had an adverse neurodevelopmental outcome, compared to 6 (24\%) of 25 infants with a duration of PVE of 7-14 days, and 6 (43\%) of 14 infants with a duration of PVE>14 days (P<0.002, RR 7.920, 95\% CI 1.017-61.661; P<0.001, RR 14.143, 95\% CI 1.871-106.895, respectively). CONCLUSION: The duration, but not the grading, of transient PVE was significantly correlated with neurodevelopmental outcome.

@article{Resch2006, abstract = {BACKGROUND: Transient periventricular echodensities (PVE) in preterm infants affect neurodevelopmental outcome. OBJECTIVE: To correlate the duration and grading of PVE with neurodevelopmental outcome. MATERIALS AND METHODS: A retrospective, single-centre cohort study of infants with PVE diagnosed by ultrasonography from 1995 to 2000 with blinded grading and recognition of duration of PVE. RESULTS: A total of 72 infants (median gestational age 32 weeks, median birth weight 1,668 g) were diagnosed as having PVE. Minor neurological abnormalities were diagnosed in seven (10\%), cerebral palsy in six (8\%), developmental delay in seven (10\%), and mild mental retardation in two (3\%) of the infants. Differences regarding adverse outcome were not significant between infants with severity grade 1 compared to severity grade 2 (16\% and 22\%, respectively). There was a significant increase in adverse neurodevelopmental outcome with increasing duration of PVE. Of 33 infants with duration of PVE<7 days, 1 (3\%) had an adverse neurodevelopmental outcome, compared to 6 (24\%) of 25 infants with a duration of PVE of 7-14 days, and 6 (43\%) of 14 infants with a duration of PVE>14 days (P<0.002, RR 7.920, 95\% CI 1.017-61.661; P<0.001, RR 14.143, 95\% CI 1.871-106.895, respectively). CONCLUSION: The duration, but not the grading, of transient PVE was significantly correlated with neurodevelopmental outcome.}, added-at = {2014-07-19T21:08:21.000+0200}, author = {Resch, Bernhard and Jammernegg, Andrea and Perl, Eva and Riccabona, Michael and Maurer, Ute and M?ller, Wilhelm D}, biburl = {https://www.bibsonomy.org/bibtex/2ff734d3fbf721b3a3210f355e0247a5f/ar0berts}, doi = {10.1007/s00247-006-0178-2}, groups = {public}, interhash = {07d1c97020800cbd67be7b3f4fe231a6}, intrahash = {ff734d3fbf721b3a3210f355e0247a5f}, journal = {Pediatr Radiol}, keywords = {Cerebral Palsy; Ventricles; Cohort Studies; Developmental Disabilities; Echoencephalography; Female; Humans; Infant, Newborn; Premature; Premature, Diseases; Leukomalacia, Periventricular; Male; Mental Retardation; Pregnancy; Prognosis; Retrospective Studies}, month = Aug, number = 8, pages = {810--815}, pmid = {16767402}, timestamp = {2014-07-19T21:08:21.000+0200}, title = {Correlation of grading and duration of periventricular echodensities with neurodevelopmental outcome in preterm infants.}, url = {http://dx.doi.org/10.1007/s00247-006-0178-2}, username = {ar0berts}, volume = 36, year = 2006 }