%0 Journal Article %1 Fortin:2015:Genome-Biol:26316348 %A Fortin, J P %A Hansen, K D %D 2015 %J Genome Biol %K MUSTREAD epic fulltext illumina methylation microarray minfi quality-control software %P 180-180 %R 10.1186/s13059-015-0741-y %T Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data %U https://www.ncbi.nlm.nih.gov/pubmed/26316348 %V 16 %X Analysis of Hi-C data has shown that the genome can be divided into two compartments called A/B compartments. These compartments are cell-type specific and are associated with open and closed chromatin. We show that A/B compartments can reliably be estimated using epigenetic data from several different platforms: the Illumina 450 k DNA methylation microarray, DNase hypersensitivity sequencing, single-cell ATAC sequencing and single-cell whole-genome bisulfite sequencing. We do this by exploiting that the structure of long-range correlations differs between open and closed compartments. This work makes A/B compartment assignment readily available in a wide variety of cell types, including many human cancers.

@article{Fortin:2015:Genome-Biol:26316348, abstract = {Analysis of Hi-C data has shown that the genome can be divided into two compartments called A/B compartments. These compartments are cell-type specific and are associated with open and closed chromatin. We show that A/B compartments can reliably be estimated using epigenetic data from several different platforms: the Illumina 450 k DNA methylation microarray, DNase hypersensitivity sequencing, single-cell ATAC sequencing and single-cell whole-genome bisulfite sequencing. We do this by exploiting that the structure of long-range correlations differs between open and closed compartments. This work makes A/B compartment assignment readily available in a wide variety of cell types, including many human cancers. }, added-at = {2018-07-22T16:23:06.000+0200}, author = {Fortin, J P and Hansen, K D}, biburl = {https://www.bibsonomy.org/bibtex/2dc4df4fddd2de15ca4229abb0dff9916/marcsaric}, description = {Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data. - PubMed - NCBI}, doi = {10.1186/s13059-015-0741-y}, interhash = {0e8207e201744c1c0cb6c194ef6360bf}, intrahash = {dc4df4fddd2de15ca4229abb0dff9916}, journal = {Genome Biol}, keywords = {MUSTREAD epic fulltext illumina methylation microarray minfi quality-control software}, month = aug, pages = {180-180}, pmid = {26316348}, timestamp = {2018-07-22T16:23:06.000+0200}, title = {Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data}, url = {https://www.ncbi.nlm.nih.gov/pubmed/26316348}, volume = 16, year = 2015 }