%0 Journal Article %1 davison_enhanced_2002 %A Davison, K L %A Crowcroft, N S %A Ramsay, M E %A Begg, N T %A Kaczmarski, E B %A Stuart, J M %A White, J M %A Orr, H %D 2002 %J Communicable Disease and Public Health / PHLS %K Adolescent, Adult, Age Aged, C, Child, England, Factors Factors, Female, Humans, Incidence, Infant, Infections, Male, Meningococcal Middle Neisseria Newborn, Population Preschool, Risk Serogroup Surveillance, Vaccines, meningitidis, %N 3 %P 205--212 %T Enhanced surveillance scheme for suspected meningococcal disease in five regional health authorities in England: 1998 %U http://www.ncbi.nlm.nih.gov/pubmed/12434690 %V 5 %X Enhanced surveillance of meningococcal disease (ESMD) began in five English regions on 1st January 1998. The aims of the scheme were to obtain accurate incidence data and develop a robust surveillance system with which to monitor the impact of a new meningococcal serogroup C conjugate vaccine. During 1998, 2,314 suspected cases of meningococcal disease were identified. The majority (84\%) was classified as invasive meningococcal disease, with infection of N. meningitidis confirmed in 66\%. Sixteen per cent of suspected cases were subsequently given an alternative diagnosis. Age differences between those classified as meningococcal disease and those not, implied a higher index of suspicion of meningococcal disease in younger children. Regions with high rates of meningococcal disease were due to a higher rate of serogroup C. ESMD increased ascertainment of meningococcal disease and deaths. Cases were 34\% greater than identified through statutory notifications, an additional 6.8\% confirmed infections were identified than were reported to the PHLS Meningococcal Reference Unit (MRU) and deaths were 24\% greater than death registrations. These data were used to inform the national meningococcal serogroup C conjugate vaccination programme in England and Wales. In 1999 ESMD was extended to all regions of England, Wales and Northern Ireland.

@article{davison_enhanced_2002, abstract = {Enhanced surveillance of meningococcal disease {(ESMD)} began in five English regions on 1st January 1998. The aims of the scheme were to obtain accurate incidence data and develop a robust surveillance system with which to monitor the impact of a new meningococcal serogroup C conjugate vaccine. During 1998, 2,314 suspected cases of meningococcal disease were identified. The majority (84\%) was classified as invasive meningococcal disease, with infection of N. meningitidis confirmed in 66\%. Sixteen per cent of suspected cases were subsequently given an alternative diagnosis. Age differences between those classified as meningococcal disease and those not, implied a higher index of suspicion of meningococcal disease in younger children. Regions with high rates of meningococcal disease were due to a higher rate of serogroup C. {ESMD} increased ascertainment of meningococcal disease and deaths. Cases were 34\% greater than identified through statutory notifications, an additional 6.8\% confirmed infections were identified than were reported to the {PHLS} Meningococcal Reference Unit {(MRU)} and deaths were 24\% greater than death registrations. These data were used to inform the national meningococcal serogroup C conjugate vaccination programme in England and Wales. In 1999 {ESMD} was extended to all regions of England, Wales and Northern Ireland.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {Davison, K L and Crowcroft, N S and Ramsay, M E and Begg, N T and Kaczmarski, E B and Stuart, J M and White, J M and Orr, H}, biburl = {https://www.bibsonomy.org/bibtex/2a8751c435b995c5f4e7b1010f879ff42/jelias}, interhash = {56e46f404516f0c755e4b8a90e7fe7b1}, intrahash = {a8751c435b995c5f4e7b1010f879ff42}, issn = {1462-1843}, journal = {Communicable Disease and Public Health / {PHLS}}, keywords = {Adolescent, Adult, Age Aged, C, Child, England, Factors Factors, Female, Humans, Incidence, Infant, Infections, Male, Meningococcal Middle Neisseria Newborn, Population Preschool, Risk Serogroup Surveillance, Vaccines, meningitidis,}, month = sep, note = {{PMID:} 12434690}, number = 3, pages = {205--212}, shorttitle = {Enhanced surveillance scheme for suspected meningococcal disease in five regional health authorities in England}, timestamp = {2011-03-11T10:05:56.000+0100}, title = {Enhanced surveillance scheme for suspected meningococcal disease in five regional health authorities in England: 1998}, url = {http://www.ncbi.nlm.nih.gov/pubmed/12434690}, volume = 5, year = 2002 }