%0 Journal Article %1 Burguet1999 %A Burguet, A. %A Monnet, E. %A Pauchard, J. Y. %A Roth, P. %A Fromentin, C. %A Dalphin, M. L. %A Allemand, H. %A Maillet, R. %A Menget, A. %D 1999 %J Biol Neonate %K Birth Weight; Cerebral Palsy; Cohort Studies; Female; Fetal Membranes, Premature Rupture; France; Gestational Age; Humans; Infant, Newborn; Premature, Diseases; Logistic Models; Male; Maternal Welfare; Mental Retardation; Multivariate Analysis; Placentation; Pregnancy; Pregnancy, Multiple; Prospective Respiratory Distress Syndrome, Risk Factors; Sex Socioeconomic Twins, Monozygotic %N 3 %P 177--186 %T Some risk factors for cerebral palsy in very premature infants: importance of premature rupture of membranes and monochorionic twin placentation. %V 75 %X OBJECTIVE: To delineate the perinatal risk factors of neurodevelopmental disabilities in very preterm birth applying logistic regression analysis. DESIGN: This prospective, geographically defined collaborative study was carried out in the Franche-Comt? region of France. Subjects: From October 1, 1990 to September 30, 1992, perinatal and follow-up data were collected on 203 consecutive live-born singleton or twin non-malformed infants with strictly ascertained gestational ages of less than 33 weeks. Main Outcome Measure: The rate of cerebral palsy and/or severe mental retardation as diagnosed by a family physician or pediatrician with a screening-skill test performed at 2 years of age. RESULTS: 167/171 (98\%) survivors were evaluated. Twenty-two of the 167 examined infants (13\%) showed signs of cerebral palsy, and 10 of these had severe cerebral palsy or mental retardation. Risk factors for disabilities were selected by a multivariate approach: premature rupture of membranes >/=48 h (OR 4.3, 95\% CI 1.6-11.8); monochorionic twin placentation (OR 6.0, 95\% CI 1.7-21.3), and respiratory distress syndrome (OR 2.8, 95\% CI 1.1-7.1). CONCLUSION: This geographically defined prospective study gives epidemiological data and highly suggests that there is a link between prenatal events (premature rupture of membranes, monochorionic twin placentation), postnatal events (respiratory distress syndrome), and neurological disabilities in former preterm infants.

@article{Burguet1999, abstract = {OBJECTIVE: To delineate the perinatal risk factors of neurodevelopmental disabilities in very preterm birth applying logistic regression analysis. DESIGN: This prospective, geographically defined collaborative study was carried out in the Franche-Comt? region of France. Subjects: From October 1, 1990 to September 30, 1992, perinatal and follow-up data were collected on 203 consecutive live-born singleton or twin non-malformed infants with strictly ascertained gestational ages of less than 33 weeks. Main Outcome Measure: The rate of cerebral palsy and/or severe mental retardation as diagnosed by a family physician or pediatrician with a screening-skill test performed at 2 years of age. RESULTS: 167/171 (98\%) survivors were evaluated. Twenty-two of the 167 examined infants (13\%) showed signs of cerebral palsy, and 10 of these had severe cerebral palsy or mental retardation. Risk factors for disabilities were selected by a multivariate approach: premature rupture of membranes >/=48 h (OR 4.3, 95\% CI 1.6-11.8); monochorionic twin placentation (OR 6.0, 95\% CI 1.7-21.3), and respiratory distress syndrome (OR 2.8, 95\% CI 1.1-7.1). CONCLUSION: This geographically defined prospective study gives epidemiological data and highly suggests that there is a link between prenatal events (premature rupture of membranes, monochorionic twin placentation), postnatal events (respiratory distress syndrome), and neurological disabilities in former preterm infants.}, added-at = {2014-07-19T19:12:59.000+0200}, author = {Burguet, A. and Monnet, E. and Pauchard, J. Y. and Roth, P. and Fromentin, C. and Dalphin, M. L. and Allemand, H. and Maillet, R. and Menget, A.}, biburl = {https://www.bibsonomy.org/bibtex/2ab8055e61b592793c3b9bdbb707cf754/ar0berts}, groups = {public}, interhash = {17256d47fed15a51d225e0c95d88f909}, intrahash = {ab8055e61b592793c3b9bdbb707cf754}, journal = {Biol Neonate}, keywords = {Birth Weight; Cerebral Palsy; Cohort Studies; Female; Fetal Membranes, Premature Rupture; France; Gestational Age; Humans; Infant, Newborn; Premature, Diseases; Logistic Models; Male; Maternal Welfare; Mental Retardation; Multivariate Analysis; Placentation; Pregnancy; Pregnancy, Multiple; Prospective Respiratory Distress Syndrome, Risk Factors; Sex Socioeconomic Twins, Monozygotic}, month = Mar, number = 3, pages = {177--186}, pii = {bon75177}, pmid = {9925905}, timestamp = {2014-07-19T19:12:59.000+0200}, title = {Some risk factors for cerebral palsy in very premature infants: importance of premature rupture of membranes and monochorionic twin placentation.}, username = {ar0berts}, volume = 75, year = 1999 }