%0 Journal Article %1 Tasdemir2001 %A Tasdemir, H. A. %A Buyukavci, M. %A Akcay, F. %A Polat, P. %A Yildiran, A. %A Karakelleoglu, C. %D 2001 %J Pediatr Int %K Alkaline Phosphatase; Bone Density; Diseases, Metabolic; Calcifediol; Calcium; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Male; Parathyroid Hormone; Phosphates %N 2 %P 157--160 %T Bone mineral density in children with cerebral palsy. %V 43 %X BACKGROUND: The purpose of the present study was to evaluate the severity of and factors related to osteopenia in children with cerebral palsy (CP). METHODS: Bone mineral density (BMD), calcium (Ca), phosphate (P), alkaline phosphatase (ALP), creatinine, parathyroid hormone (PTH) and 25-hydroxy vitamin D3 (25OHD3) concentrations were determined in 24 children with CP (15 ambulant, nine non-ambulant), aged between 10 months and 12 years (mean (+/-SD) 4.1+/-2.9 years). These vaules were compared with data obtained from a control group. RESULTS: Adjusted mean BMD values were lower in the patient group than in controls (P<0.05). However, there was no difference between BMD values of ambulant and non-ambulant patients. The Ca and P levels of the patient group were significantly higher than those of controls (P<0.05). CONCLUSIONS: The present study showed that BMD was decreased in all children with CP, but to a greater extent in non-ambulant children with CP, and immobilization is the major effective factor on bone mineralization.

@article{Tasdemir2001, abstract = {BACKGROUND: The purpose of the present study was to evaluate the severity of and factors related to osteopenia in children with cerebral palsy (CP). METHODS: Bone mineral density (BMD), calcium (Ca), phosphate (P), alkaline phosphatase (ALP), creatinine, parathyroid hormone (PTH) and 25-hydroxy vitamin D3 (25OHD3) concentrations were determined in 24 children with CP (15 ambulant, nine non-ambulant), aged between 10 months and 12 years (mean (+/-SD) 4.1+/-2.9 years). These vaules were compared with data obtained from a control group. RESULTS: Adjusted mean BMD values were lower in the patient group than in controls (P<0.05). However, there was no difference between BMD values of ambulant and non-ambulant patients. The Ca and P levels of the patient group were significantly higher than those of controls (P<0.05). CONCLUSIONS: The present study showed that BMD was decreased in all children with CP, but to a greater extent in non-ambulant children with CP, and immobilization is the major effective factor on bone mineralization.}, added-at = {2014-07-19T21:42:30.000+0200}, author = {Tasdemir, H. A. and Buyukavci, M. and Akcay, F. and Polat, P. and Yildiran, A. and Karakelleoglu, C.}, biburl = {https://www.bibsonomy.org/bibtex/214ee9090f13e0922b958c3e3137ec6d3/ar0berts}, groups = {public}, interhash = {1ad644c0b5a46d1ac54d53f3a70924db}, intrahash = {14ee9090f13e0922b958c3e3137ec6d3}, journal = {Pediatr Int}, keywords = {Alkaline Phosphatase; Bone Density; Diseases, Metabolic; Calcifediol; Calcium; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Male; Parathyroid Hormone; Phosphates}, month = Apr, number = 2, pages = {157--160}, pii = {ped1352}, pmid = {11285068}, timestamp = {2014-07-19T21:42:30.000+0200}, title = {Bone mineral density in children with cerebral palsy.}, username = {ar0berts}, volume = 43, year = 2001 }