Health-care-associated infections caused by antibiotic-resistant pathogens have become a menace in hospitals worldwide and infection control measures have lead to vastly different outcomes in different countries. During the past 6 years, a theoretical framework based on mathematical models has emerged that provides solid and testable hypotheses and opens the road to a quantitative assessment of the main obstructions that undermine current efforts to control the spread of health-care-associated infections in hospitals and communities. We aim to explain to a broader audience of professionals in health care, infection control, and health systems administration some of these models that can improve the understanding of the hidden dynamics of health-care-associated infections. We also appraise their usefulness and limitations as an innovative research and decision tool for control purposes.
%0 Journal Article
%1 grundmann_mathematical_2006
%A Grundmann, H
%A Hellriegel, B
%D 2006
%J The Lancet Infectious Diseases
%K Control, Cross Decision Epidemiologic Humans, Infection Infection, Making, Methods, Models, Theoretical
%N 1
%P 39--45
%R S1473-3099(05)70325-X
%T Mathematical modelling: a tool for hospital infection control
%U http://www.ncbi.nlm.nih.gov/pubmed/16377533
%V 6
%X Health-care-associated infections caused by antibiotic-resistant pathogens have become a menace in hospitals worldwide and infection control measures have lead to vastly different outcomes in different countries. During the past 6 years, a theoretical framework based on mathematical models has emerged that provides solid and testable hypotheses and opens the road to a quantitative assessment of the main obstructions that undermine current efforts to control the spread of health-care-associated infections in hospitals and communities. We aim to explain to a broader audience of professionals in health care, infection control, and health systems administration some of these models that can improve the understanding of the hidden dynamics of health-care-associated infections. We also appraise their usefulness and limitations as an innovative research and decision tool for control purposes.
@article{grundmann_mathematical_2006,
abstract = {Health-care-associated infections caused by antibiotic-resistant pathogens have become a menace in hospitals worldwide and infection control measures have lead to vastly different outcomes in different countries. During the past 6 years, a theoretical framework based on mathematical models has emerged that provides solid and testable hypotheses and opens the road to a quantitative assessment of the main obstructions that undermine current efforts to control the spread of health-care-associated infections in hospitals and communities. We aim to explain to a broader audience of professionals in health care, infection control, and health systems administration some of these models that can improve the understanding of the hidden dynamics of health-care-associated infections. We also appraise their usefulness and limitations as an innovative research and decision tool for control purposes.},
added-at = {2011-03-11T10:05:34.000+0100},
author = {Grundmann, H and Hellriegel, B},
biburl = {https://www.bibsonomy.org/bibtex/20d57239939f4b26e0e1dd8cf6901f8ee/jelias},
doi = {S1473-3099(05)70325-X},
interhash = {bc97eb7cc694cee3325f00de1cd011af},
intrahash = {0d57239939f4b26e0e1dd8cf6901f8ee},
issn = {1473-3099},
journal = {The Lancet Infectious Diseases},
keywords = {Control, Cross Decision Epidemiologic Humans, Infection Infection, Making, Methods, Models, Theoretical},
month = jan,
note = {{PMID:} 16377533},
number = 1,
pages = {39--45},
shorttitle = {Mathematical modelling},
timestamp = {2011-03-11T10:06:23.000+0100},
title = {Mathematical modelling: a tool for hospital infection control},
url = {http://www.ncbi.nlm.nih.gov/pubmed/16377533},
volume = 6,
year = 2006
}