%0 Journal Article %1 baker_genome_2007 %A Baker, Stephen %A Dougan, Gordon %D 2007 %J Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America %K Alignment, Analysis, Antigens, Bacterial, Escherichia Genome, Humans, Interactions, Polysaccharides, Salmonella Sequence Virulence coli, typhi, typhimurium, {DNA,} {Host-Parasite} %P S29--33 %R CID50032 %T The genome of Salmonella enterica serovar Typhi %V 45 Suppl 1 %X The generation of complete genome sequences provides a blueprint that facilitates the genetic characterization of pathogens and their hosts. The genome of Salmonella enterica serovar Typhi (S. Typhi) harbors ˜5 million base pairs encoding some 4000 genes, of which \textgreater200 are functionally inactive. Comparison of S. Typhi isolates from around the world indicates that they are highly related (clonal) and that they emerged from a single point of origin ˜30,000-50,000 years ago. Evidence suggests that, as well as undergoing gene degradation, S. Typhi has also recently acquired genes, such as those encoding the Vi antigen, by horizontal transfer events.

@article{baker_genome_2007, abstract = {The generation of complete genome sequences provides a blueprint that facilitates the genetic characterization of pathogens and their hosts. The genome of Salmonella enterica serovar Typhi {(S.} Typhi) harbors {\textasciitilde}5 million base pairs encoding some 4000 genes, of which {\textgreater}200 are functionally inactive. Comparison of S. Typhi isolates from around the world indicates that they are highly related (clonal) and that they emerged from a single point of origin {\textasciitilde}30,000-50,000 years ago. Evidence suggests that, as well as undergoing gene degradation, S. Typhi has also recently acquired genes, such as those encoding the Vi antigen, by horizontal transfer events.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {Baker, Stephen and Dougan, Gordon}, biburl = {https://www.bibsonomy.org/bibtex/239658a0286c88938dede27b1ba0192fd/jelias}, doi = {CID50032}, interhash = {8f4e5c3038bd544d8bbfb83c489b1abf}, intrahash = {39658a0286c88938dede27b1ba0192fd}, issn = {1537-6591}, journal = {Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America}, keywords = {Alignment, Analysis, Antigens, Bacterial, Escherichia Genome, Humans, Interactions, Polysaccharides, Salmonella Sequence Virulence coli, typhi, typhimurium, {DNA,} {Host-Parasite}}, month = jul, note = {{PMID:} 17582565}, pages = {S29--33}, timestamp = {2011-03-11T10:06:28.000+0100}, title = {The genome of Salmonella enterica serovar Typhi}, volume = {45 Suppl 1}, year = 2007 }