In the literature, there are few studies on atherosclerosis in the pulmonary artery in human beings, especially in aging. The aim of the study was to report the anatomic pathological aspects of an old patient who had severe pulmonary atherosclerosis associated with an atrial septal defect (ASD). The patient had marked atherosclerosis in the pulmonary trunk and its branches, probably caused by a series of hemodynamic and endothelial changes, subsequent to the ASD. The left to right shunt could have caused an increase in the blood flow and pulmonary hypertension, intensified by the vascular alterations in the region. This hypertension probably became intense to the point of reversing the direction of the shunt, from the right to the left, characterizing a probable Eisenmenger syndrome, responsible for the patient's dyspnea and cyanosis. Our study demonstrates a condition that is especially infrequent because of the patient's age of 64 years and, thus, adds to the literature.
Beschreibung
Pulmonary atherosclerosis associated with a... [Pathol Res Pract. 2009] - PubMed - NCBI
%0 Journal Article
%1 Nascimento:2009:Pathol-Res-Pract:18947936
%A Nascimento, D
%A Nunes, L
%A Oliveira, F
%A Vencio, E
%A Teixeira, V
%A Reis, M
%D 2009
%J Pathol Res Pract
%K atherosclerosis atrial_septal_defect pulmonary_artery pulmonary_hypertension
%N 2
%P 137-141
%R 10.1016/j.prp.2008.07.008
%T Pulmonary atherosclerosis associated with an atrial septal defect in old age: case report of an elderly autopsied patient
%U http://www.ncbi.nlm.nih.gov/pubmed/18947936
%V 205
%X In the literature, there are few studies on atherosclerosis in the pulmonary artery in human beings, especially in aging. The aim of the study was to report the anatomic pathological aspects of an old patient who had severe pulmonary atherosclerosis associated with an atrial septal defect (ASD). The patient had marked atherosclerosis in the pulmonary trunk and its branches, probably caused by a series of hemodynamic and endothelial changes, subsequent to the ASD. The left to right shunt could have caused an increase in the blood flow and pulmonary hypertension, intensified by the vascular alterations in the region. This hypertension probably became intense to the point of reversing the direction of the shunt, from the right to the left, characterizing a probable Eisenmenger syndrome, responsible for the patient's dyspnea and cyanosis. Our study demonstrates a condition that is especially infrequent because of the patient's age of 64 years and, thus, adds to the literature.
@article{Nascimento:2009:Pathol-Res-Pract:18947936,
abstract = {In the literature, there are few studies on atherosclerosis in the pulmonary artery in human beings, especially in aging. The aim of the study was to report the anatomic pathological aspects of an old patient who had severe pulmonary atherosclerosis associated with an atrial septal defect (ASD). The patient had marked atherosclerosis in the pulmonary trunk and its branches, probably caused by a series of hemodynamic and endothelial changes, subsequent to the ASD. The left to right shunt could have caused an increase in the blood flow and pulmonary hypertension, intensified by the vascular alterations in the region. This hypertension probably became intense to the point of reversing the direction of the shunt, from the right to the left, characterizing a probable Eisenmenger syndrome, responsible for the patient's dyspnea and cyanosis. Our study demonstrates a condition that is especially infrequent because of the patient's age of 64 years and, thus, adds to the literature.},
added-at = {2013-04-03T21:28:07.000+0200},
author = {Nascimento, D and Nunes, L and Oliveira, F and Vencio, E and Teixeira, V and Reis, M},
biburl = {https://www.bibsonomy.org/bibtex/2416413824a1c8ce49350c81ff6b032dc/iskanbasal},
description = {Pulmonary atherosclerosis associated with a... [Pathol Res Pract. 2009] - PubMed - NCBI},
doi = {10.1016/j.prp.2008.07.008},
interhash = {9cff2b3483a4f2c790aec1885fae2c26},
intrahash = {416413824a1c8ce49350c81ff6b032dc},
journal = {Pathol Res Pract},
keywords = {atherosclerosis atrial_septal_defect pulmonary_artery pulmonary_hypertension},
number = 2,
pages = {137-141},
pmid = {18947936},
timestamp = {2013-04-03T21:28:07.000+0200},
title = {Pulmonary atherosclerosis associated with an atrial septal defect in old age: case report of an elderly autopsied patient},
url = {http://www.ncbi.nlm.nih.gov/pubmed/18947936},
volume = 205,
year = 2009
}