\textlessAbstractText Label="BACKGROUND" NlmCategory="BACKGROUND"\textgreaterTo our best knowledge, Panton-Valentine leucocidin (PVL)-positive methicillin-sensitive Staphylococcus aureus (MSSA) has not been described yet as cause for severe pyomyositis.\textless/AbstractText\textgreater
\textlessAbstractText Label="CASE REPORT" NlmCategory="METHODS"\textgreaterWe present a 23-year-old apparently healthy male patient without any typical predisposing findings who developed severe pyomyositis secondary to an operated pilonidal cyst. In the follow-up, the patient showed signs of immunocompromisation. The causative agent for purulent infection of multiple muscles was a MSSA strain harbouring PVL toxin.\textless/AbstractText\textgreater
\textlessAbstractText Label="RESULTS" NlmCategory="RESULTS"\textgreaterIn the reported case, aggressive antibiotic and surgical treatment with additional application of immunoglobulins has lead to recovery from the disease without relapse.\textless/AbstractText\textgreater
\textlessAbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS"\textgreaterPVL-positive S. aureus are associated with skin diseases, multiple abscesses and often complicated by severe sepsis and necrotising pneumonia. Under such circumstances, the mortality rate can reach up to 75\%. In addition, the PVL toxin can cause immunocompromisation and might be therefore involved in the aetiology of pyomyositis. Aggressive antibiotic and surgical treatment with additional application of immunoglobulins is recommended for treatment.\textless/AbstractText\textgreater
%0 Journal Article
%1 lorenz_severe_2007
%A Lorenz, Udo
%A Abele-Horn, Marianne
%A Bussen, Dieter
%A Thiede, Arnulf
%D 2007
%J Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie
%K Abscess, Adult, Bacterial Bacteriological Buttocks, Complications, Debridement, Diagnosis, Differential, Disease Drainage, Early Exotoxins, Humans, Imaging, Infections, Leukocidins, Magnetic Male, Methicillin Pilonidal Postoperative Progression, Pyomyositis, Reoperation, Resistance, Resonance Sepsis, Sinus, Staphylococcal Staphylococcus Techniques, Toxins, Virulence ag_horn aureus,
%N 6
%P 761--765
%R 10.1007/s00423-007-0212-3
%T Severe pyomyositis caused by Panton-Valentine leucocidin-positive methicillin-sensitive Staphylococcus aureus complicating a pilonidal cyst
%U http://www.ncbi.nlm.nih.gov/pubmed/17661075
%V 392
%X \textlessAbstractText Label="BACKGROUND" NlmCategory="BACKGROUND"\textgreaterTo our best knowledge, Panton-Valentine leucocidin (PVL)-positive methicillin-sensitive Staphylococcus aureus (MSSA) has not been described yet as cause for severe pyomyositis.\textless/AbstractText\textgreater
\textlessAbstractText Label="CASE REPORT" NlmCategory="METHODS"\textgreaterWe present a 23-year-old apparently healthy male patient without any typical predisposing findings who developed severe pyomyositis secondary to an operated pilonidal cyst. In the follow-up, the patient showed signs of immunocompromisation. The causative agent for purulent infection of multiple muscles was a MSSA strain harbouring PVL toxin.\textless/AbstractText\textgreater
\textlessAbstractText Label="RESULTS" NlmCategory="RESULTS"\textgreaterIn the reported case, aggressive antibiotic and surgical treatment with additional application of immunoglobulins has lead to recovery from the disease without relapse.\textless/AbstractText\textgreater
\textlessAbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS"\textgreaterPVL-positive S. aureus are associated with skin diseases, multiple abscesses and often complicated by severe sepsis and necrotising pneumonia. Under such circumstances, the mortality rate can reach up to 75\%. In addition, the PVL toxin can cause immunocompromisation and might be therefore involved in the aetiology of pyomyositis. Aggressive antibiotic and surgical treatment with additional application of immunoglobulins is recommended for treatment.\textless/AbstractText\textgreater
@article{lorenz_severe_2007,
abstract = {{{\textless}AbstractText} {Label="BACKGROUND"} {NlmCategory="BACKGROUND"{\textgreater}To} our best knowledge, {Panton-Valentine} leucocidin {(PVL)-positive} methicillin-sensitive Staphylococcus aureus {(MSSA)} has not been described yet as cause for severe {pyomyositis.{\textless}/AbstractText{\textgreater}}
{{\textless}AbstractText} {Label="CASE} {REPORT"} {NlmCategory="METHODS"{\textgreater}We} present a 23-year-old apparently healthy male patient without any typical predisposing findings who developed severe pyomyositis secondary to an operated pilonidal cyst. In the follow-up, the patient showed signs of immunocompromisation. The causative agent for purulent infection of multiple muscles was a {MSSA} strain harbouring {PVL} {toxin.{\textless}/AbstractText{\textgreater}}
{{\textless}AbstractText} {Label="RESULTS"} {NlmCategory="RESULTS"{\textgreater}In} the reported case, aggressive antibiotic and surgical treatment with additional application of immunoglobulins has lead to recovery from the disease without {relapse.{\textless}/AbstractText{\textgreater}}
{{\textless}AbstractText} {Label="CONCLUSIONS"} {NlmCategory="CONCLUSIONS"{\textgreater}PVL-positive} S. aureus are associated with skin diseases, multiple abscesses and often complicated by severe sepsis and necrotising pneumonia. Under such circumstances, the mortality rate can reach up to 75\%. In addition, the {PVL} toxin can cause immunocompromisation and might be therefore involved in the aetiology of pyomyositis. Aggressive antibiotic and surgical treatment with additional application of immunoglobulins is recommended for {treatment.{\textless}/AbstractText{\textgreater}}},
added-at = {2011-04-07T15:44:20.000+0200},
author = {Lorenz, Udo and {Abele-Horn}, Marianne and Bussen, Dieter and Thiede, Arnulf},
biburl = {https://www.bibsonomy.org/bibtex/24bc346d2bf18005ddf20b5046dd12de5/hymi},
doi = {10.1007/s00423-007-0212-3},
interhash = {83427ec00256f9f87fd2a1676897cb02},
intrahash = {4bc346d2bf18005ddf20b5046dd12de5},
issn = {1435-2451},
journal = {Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie},
keywords = {Abscess, Adult, Bacterial Bacteriological Buttocks, Complications, Debridement, Diagnosis, Differential, Disease Drainage, Early Exotoxins, Humans, Imaging, Infections, Leukocidins, Magnetic Male, Methicillin Pilonidal Postoperative Progression, Pyomyositis, Reoperation, Resistance, Resonance Sepsis, Sinus, Staphylococcal Staphylococcus Techniques, Toxins, Virulence ag_horn aureus,},
month = nov,
note = {{PMID:} 17661075},
number = 6,
pages = {761--765},
timestamp = {2011-04-07T16:35:57.000+0200},
title = {Severe pyomyositis caused by {Panton-Valentine} leucocidin-positive methicillin-sensitive Staphylococcus aureus complicating a pilonidal cyst},
url = {http://www.ncbi.nlm.nih.gov/pubmed/17661075},
volume = 392,
year = 2007
}